JPWO2022218384A5 - - Google Patents

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Publication number
JPWO2022218384A5
JPWO2022218384A5 JP2023514956A JP2023514956A JPWO2022218384A5 JP WO2022218384 A5 JPWO2022218384 A5 JP WO2022218384A5 JP 2023514956 A JP2023514956 A JP 2023514956A JP 2023514956 A JP2023514956 A JP 2023514956A JP WO2022218384 A5 JPWO2022218384 A5 JP WO2022218384A5
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JP
Japan
Prior art keywords
seq
variant
antibody
amino acid
variable region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023514956A
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English (en)
Japanese (ja)
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JP2024515396A (ja
JP2024515396A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/086890 external-priority patent/WO2022218384A1/zh
Publication of JP2024515396A publication Critical patent/JP2024515396A/ja
Publication of JP2024515396A5 publication Critical patent/JP2024515396A5/ja
Publication of JPWO2022218384A5 publication Critical patent/JPWO2022218384A5/ja
Pending legal-status Critical Current

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JP2023514956A 2021-04-14 2022-04-14 抗ｃｄ４７モノクローナル抗体及びその使用 Pending JP2024515396A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202110404033.2 2021-04-14
CN202110404033 2021-04-14
PCT/CN2022/086890 WO2022218384A1 (zh) 2021-04-14 2022-04-14 抗cd47的单克隆抗体及其用途

Publications (3)

Publication Number Publication Date
JP2024515396A JP2024515396A (ja) 2024-04-10
JP2024515396A5 JP2024515396A5 (https=) 2025-02-28
JPWO2022218384A5 true JPWO2022218384A5 (https=) 2025-02-28

Family

ID=83575257

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023514956A Pending JP2024515396A (ja) 2021-04-14 2022-04-14 抗ｃｄ４７モノクローナル抗体及びその使用

Country Status (11)

Country Link
US (1) US20240043531A1 (https=)
EP (1) EP4190816A4 (https=)
JP (1) JP2024515396A (https=)
KR (1) KR20230170648A (https=)
CN (1) CN115192718A (https=)
AU (1) AU2022258273A1 (https=)
BR (1) BR112023018450A2 (https=)
CA (1) CA3193664A1 (https=)
IL (1) IL305363A (https=)
MX (1) MX2023010687A (https=)
WO (1) WO2022218384A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109053895B (zh) * 2018-08-30 2020-06-09 中山康方生物医药有限公司 抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途
AU2020324185A1 (en) * 2019-08-02 2022-03-03 CTTQ-Akeso (ShangHai) Biomed. Tech. Co., Ltd. Anti-PD-1 antibody and medical use thereof
JP2025530041A (ja) * 2022-09-09 2025-09-11 中山康方生物医▲藥▼有限公司 治療用組合せ物とその使用
CN119823266A (zh) * 2023-10-13 2025-04-15 英脉德医疗科技(广东)有限公司 肿瘤微环境特异激活的cd47抗体
WO2025201450A1 (zh) * 2024-03-27 2025-10-02 康方汇科(上海)生物有限公司 药物组合及用途
WO2026051964A1 (en) 2024-09-04 2026-03-12 Akeso Biopharma Co., Ltd. Antibody that binds vegfa and pd-1 and uses thereof to treat cancers

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
ATE87659T1 (de) 1986-09-02 1993-04-15 Enzon Lab Inc Bindungsmolekuele mit einzelpolypeptidkette.
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5260203A (en) 1986-09-02 1993-11-09 Enzon, Inc. Single polypeptide chain binding molecules
US5747654A (en) 1993-06-14 1998-05-05 The United States Of America As Represented By The Department Of Health And Human Services Recombinant disulfide-stabilized polypeptide fragments having binding specificity
SI4177270T1 (sl) * 2017-10-18 2024-10-30 Forty Seven, Inc. Terapija za raka jajčnikov na osnovi sredstva proti cd47
WO2019109357A1 (zh) * 2017-12-08 2019-06-13 杭州翰思生物医药有限公司 抗pd-1/cd47的双特异性抗体及其应用
CN109053895B (zh) * 2018-08-30 2020-06-09 中山康方生物医药有限公司 抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途
CN114072426B (zh) * 2019-07-08 2024-01-26 南京金斯瑞生物科技有限公司 抗cd47/抗pd-1双特异抗体及其制备方法和应用
WO2021023117A1 (zh) * 2019-08-02 2021-02-11 康方药业有限公司 抗ctla4-抗pd-1双特异性抗体及其用途
AU2020324185A1 (en) * 2019-08-02 2022-03-03 CTTQ-Akeso (ShangHai) Biomed. Tech. Co., Ltd. Anti-PD-1 antibody and medical use thereof
CN112442123B (zh) * 2019-09-03 2022-08-23 中山康方生物医药有限公司 抗cd47的单克隆抗体及其用途
US20230027029A1 (en) * 2019-11-25 2023-01-26 Akeso Biopharma, Inc. Anti-pd-1-anti-vegfa bispecific antibody, pharmaceutical composition and use thereof

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