JPWO2022216624A5 - - Google Patents
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- Publication number
- JPWO2022216624A5 JPWO2022216624A5 JP2023561609A JP2023561609A JPWO2022216624A5 JP WO2022216624 A5 JPWO2022216624 A5 JP WO2022216624A5 JP 2023561609 A JP2023561609 A JP 2023561609A JP 2023561609 A JP2023561609 A JP 2023561609A JP WO2022216624 A5 JPWO2022216624 A5 JP WO2022216624A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- ipsc
- tcr
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163171650P | 2021-04-07 | 2021-04-07 | |
| US63/171,650 | 2021-04-07 | ||
| PCT/US2022/023347 WO2022216624A1 (en) | 2021-04-07 | 2022-04-04 | Compositions and methods for generating alpha-beta t cells from induced pluripotent stem cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024513906A JP2024513906A (ja) | 2024-03-27 |
| JPWO2022216624A5 true JPWO2022216624A5 (https=) | 2025-04-11 |
| JP2024513906A5 JP2024513906A5 (https=) | 2025-04-11 |
Family
ID=81648457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023561609A Pending JP2024513906A (ja) | 2021-04-07 | 2022-04-04 | 人工多能性幹細胞からアルファ－ベータｔ細胞を生成するための組成物および方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220333074A1 (https=) |
| EP (1) | EP4320224A1 (https=) |
| JP (1) | JP2024513906A (https=) |
| CN (1) | CN117441010A (https=) |
| AR (1) | AR125313A1 (https=) |
| AU (1) | AU2022255166A1 (https=) |
| CA (1) | CA3214473A1 (https=) |
| TW (1) | TW202305114A (https=) |
| WO (1) | WO2022216624A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2021392032A1 (en) | 2020-12-03 | 2023-06-22 | Century Therapeutics, Inc. | Genetically engineered cells and uses thereof |
| US20250066738A1 (en) * | 2021-09-07 | 2025-02-27 | Dana-Farber Cancer Institute, Inc. | Induced pluripotent stem cells (ipsc), t-cell compositions and methods of use |
| IL314801A (en) | 2022-02-22 | 2024-10-01 | Juno Therapeutics Inc | Proteinase 3 (PR3) Chimeric Autoantigen Receptor T Cells and Related Methods and Uses |
| JP2025522360A (ja) | 2022-06-08 | 2025-07-15 | センチュリー セラピューティクス，インコーポレイテッド | Ｃｄ１６変異体およびｎｋｇ２ｄを発現する遺伝子操作した細胞ならびにその使用 |
| KR20250143301A (ko) | 2022-11-10 | 2025-10-01 | 센츄리 쎄라퓨틱스 인코포레이티드 | 항-넥틴4 키메라 항원 수용체를 갖는 유전자 조작 세포 및 이의 용도 |
| EP4397680A1 (en) * | 2022-12-29 | 2024-07-10 | Keshihua (Nanjing) Biotechnology Co., Ltd | Tcr, polypeptide, expression vector, host cell, pharmaceutical composition and method for obtaining tcr |
| WO2025101938A2 (en) | 2023-11-10 | 2025-05-15 | Century Therapeutics, Inc. | Genetically engineered cells having multi-transmembrane domain chimeric antigen receptors utilizing g protein-coupled receptor scaffolds, and uses thereof |
| WO2025106626A1 (en) | 2023-11-15 | 2025-05-22 | Century Therapeutics, Inc. | Genetically engineered cells expressing c-x-c chemokine receptor type 4, and uses thereof |
| WO2025237762A1 (en) | 2024-05-14 | 2025-11-20 | Englmeier Ludwig | Matched t-cells and myeloid cells from cell culture |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6344321B1 (en) | 1990-06-11 | 2002-02-05 | Gilead Sciences, Inc. | Nucleic acid ligands which bind to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met |
| AU701578B2 (en) | 1992-08-21 | 1999-02-04 | Vrije Universiteit Brussel | Immunoglobulins devoid of light chains |
| GB9710809D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| GB9710807D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| US6140081A (en) | 1998-10-16 | 2000-10-31 | The Scripps Research Institute | Zinc finger binding domains for GNN |
| US6453242B1 (en) | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| US6534261B1 (en) | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| JP2002060786A (ja) | 2000-08-23 | 2002-02-26 | Kao Corp | 硬質表面用殺菌防汚剤 |
| US20040224385A1 (en) | 2001-08-20 | 2004-11-11 | Barbas Carlos F | Zinc finger binding domains for cnn |
| US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| US7972854B2 (en) | 2004-02-05 | 2011-07-05 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| US8574179B2 (en) | 2004-09-17 | 2013-11-05 | Stp Swiss Therapeutic Products Ag | Enhanced biomechanical stimulation device |
| DK3399025T3 (da) | 2007-03-23 | 2025-06-16 | Wisconsin Alumni Res Found | Omprogrammering af somatiske celler |
| EP3279314A1 (en) | 2008-06-04 | 2018-02-07 | Cellular Dynamics International, Inc. | Methods for the production of ips cells using non-viral approach |
| CA2741090C (en) | 2008-10-24 | 2018-10-16 | Wisconsin Alumni Research Foundation | Pluripotent stem cells obtained by non-viral reprogramming |
| KR101720961B1 (ko) | 2009-02-27 | 2017-03-29 | 셀룰러 다이내믹스 인터내셔널, 인코포레이티드 | 다능성 세포의 분화 |
| EP3222617B1 (en) | 2009-03-19 | 2022-07-06 | The Johns Hopkins University | Psma-targeting compounds and uses thereof |
| HUE041436T2 (hu) | 2009-12-10 | 2019-05-28 | Univ Minnesota | Tal-effektor-közvetített DNS-módosítás |
| US9206394B2 (en) * | 2010-02-03 | 2015-12-08 | The University Of Tokyo | Method for reconstructing immune function using pluripotent stem cells |
| WO2012018933A2 (en) | 2010-08-04 | 2012-02-09 | Cellular Dynamics International, Inc. | Reprogramming immortalized b cells |
| WO2012109208A2 (en) | 2011-02-08 | 2012-08-16 | Cellular Dynamics International, Inc. | Hematopoietic precursor cell production by programming |
| DE102012006356A1 (de) | 2012-03-28 | 2013-10-02 | Audi Ag | Kraftfahrzeug, umfassend mehrere aktive oder passive Sicherheitsvorrichtungen |
| AU2014248119B2 (en) * | 2013-04-03 | 2019-06-20 | Memorial Sloan-Kettering Cancer Center | Effective generation of tumor-targeted T-cells derived from pluripotent stem cells |
| WO2015143029A1 (en) | 2014-03-18 | 2015-09-24 | The Johns Hopkins University | Psma-based molecular-genetic reporter system |
| KR102654784B1 (ko) | 2014-07-18 | 2024-04-04 | 사이아스 가부시키가이샤 | 다능성 줄기세포로부터 세포-기반 면역요법용 t 세포를 유도하는 방법 |
| CN108431211B (zh) | 2015-10-20 | 2026-03-24 | 富士胶片细胞动力公司 | 通过遗传编程的多谱系造血前体细胞产生 |
| EP3708587B1 (en) * | 2015-11-27 | 2024-05-22 | Cartherics Pty. Ltd. | Genetically modified cells and uses thereof |
| ES2886631T3 (es) | 2016-04-15 | 2021-12-20 | Univ Kyoto | Método para inducir células T positivas para CD8 específicas de antígeno |
| SG11201901642XA (en) | 2016-08-26 | 2019-03-28 | Baylor College Medicine | Constitutively active cytokine receptors for cell therapy |
| EP3510145A4 (en) | 2016-09-06 | 2020-03-25 | The Children's Medical Center Corporation | IMMUNCELLS FROM INDUCED PLURIPOTENT STEM CELLS |
| CA3035075A1 (en) | 2016-09-23 | 2018-03-29 | Fred Hutchinson Cancer Research Center | Tcrs specific for minor histocompatibility (h) antigen ha-1 and uses thereof |
| JP7212615B2 (ja) | 2016-10-05 | 2023-01-25 | フジフィルム セルラー ダイナミクス，インコーポレイテッド | 多能性幹細胞からｈｌａホモ接合免疫細胞への指向分化方法 |
| EP3607319A1 (en) | 2017-04-07 | 2020-02-12 | Juno Therapeutics, Inc. | Engineered cells expressing prostate-specific membrane antigen (psma) or a modified form thereof and related methods |
| WO2018195175A1 (en) | 2017-04-18 | 2018-10-25 | FUJIFILM Cellular Dynamics, Inc. | Antigen-specific immune effector cells |
| CN111432823A (zh) | 2017-07-25 | 2020-07-17 | 得克萨斯大学体系董事会 | 增强的嵌合抗原受体及其用途 |
| CA3076099A1 (en) | 2017-09-22 | 2019-03-28 | Kite Pharma, Inc. | Linkers for chimeric antigen receptors |
| US20200239544A1 (en) | 2017-10-03 | 2020-07-30 | Precision Biosciences, Inc. | Modified epidermal growth factor receptor peptides for use in genetically-modified cells |
| CN112739816B (zh) | 2018-09-19 | 2025-09-12 | 富士胶片细胞动力公司 | 用于激活和扩增嵌合抗原受体-修饰的免疫细胞的蛋白l |
| KR102943217B1 (ko) * | 2018-12-02 | 2026-03-25 | 페이트 세러퓨틱스, 인코포레이티드 | 향상된 iPSC 유래 효과기 세포를 사용한 면역요법 |
| JP6821230B2 (ja) * | 2019-02-04 | 2021-01-27 | 国立大学法人愛媛大学 | ＣＡＲライブラリおよびｓｃＦｖの製造方法 |
| EP3924467A1 (en) * | 2019-02-15 | 2021-12-22 | Editas Medicine, Inc. | Modified natural killer (nk) cells for immunotherapy |
| US12419954B2 (en) * | 2020-01-31 | 2025-09-23 | City Of Hope | Targeted chimeric antigen receptor modified T cells for treatment of IL13Rα2 positive malignancies |
-
2022
- 2022-04-04 US US17/657,801 patent/US20220333074A1/en active Pending
- 2022-04-04 WO PCT/US2022/023347 patent/WO2022216624A1/en not_active Ceased
- 2022-04-04 AU AU2022255166A patent/AU2022255166A1/en not_active Abandoned
- 2022-04-04 CA CA3214473A patent/CA3214473A1/en active Pending
- 2022-04-04 JP JP2023561609A patent/JP2024513906A/ja active Pending
- 2022-04-04 EP EP22723252.7A patent/EP4320224A1/en active Pending
- 2022-04-04 CN CN202280040273.1A patent/CN117441010A/zh active Pending
- 2022-04-07 TW TW111113296A patent/TW202305114A/zh unknown
- 2022-04-07 AR ARP220100877A patent/AR125313A1/es unknown
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