JPWO2022204429A5 - - Google Patents

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Publication number
JPWO2022204429A5
JPWO2022204429A5 JP2023558983A JP2023558983A JPWO2022204429A5 JP WO2022204429 A5 JPWO2022204429 A5 JP WO2022204429A5 JP 2023558983 A JP2023558983 A JP 2023558983A JP 2023558983 A JP2023558983 A JP 2023558983A JP WO2022204429 A5 JPWO2022204429 A5 JP WO2022204429A5
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JP
Japan
Prior art keywords
item
nucleotides
length
molecule
sense strand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023558983A
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English (en)
Japanese (ja)
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JP2024512612A5 (https=
JP2024512612A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/021789 external-priority patent/WO2022204429A1/en
Publication of JP2024512612A publication Critical patent/JP2024512612A/ja
Publication of JP2024512612A5 publication Critical patent/JP2024512612A5/ja
Publication of JPWO2022204429A5 publication Critical patent/JPWO2022204429A5/ja
Pending legal-status Critical Current

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JP2023558983A 2021-03-24 2022-03-24 二本鎖siRNAを使用したミクログリア遺伝子サイレンシング Pending JP2024512612A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163165518P 2021-03-24 2021-03-24
US63/165,518 2021-03-24
PCT/US2022/021789 WO2022204429A1 (en) 2021-03-24 2022-03-24 Microglial gene silencing using double-stranded sirna

Publications (3)

Publication Number Publication Date
JP2024512612A JP2024512612A (ja) 2024-03-19
JP2024512612A5 JP2024512612A5 (https=) 2025-04-01
JPWO2022204429A5 true JPWO2022204429A5 (https=) 2025-04-01

Family

ID=83397877

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023558983A Pending JP2024512612A (ja) 2021-03-24 2022-03-24 二本鎖siRNAを使用したミクログリア遺伝子サイレンシング

Country Status (7)

Country Link
US (1) US20240200063A1 (https=)
EP (1) EP4313070A4 (https=)
JP (1) JP2024512612A (https=)
CN (1) CN117835986A (https=)
AU (1) AU2022246147A1 (https=)
CA (1) CA3214657A1 (https=)
WO (1) WO2022204429A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118374495A (zh) * 2024-03-28 2024-07-23 深圳脑健生物技术有限公司 一种抑制NLRP3基因表达的siRNA及其前体和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006055727A2 (en) * 2004-11-18 2006-05-26 The Board Of Trustees Of The University Of Illinois MULTICISTRONIC siRNA CONSTRUCTS TO INHIBIT TUMORS
SMT202000454T1 (it) * 2015-04-03 2020-11-10 Univ Massachusetts Cmposti oligonucleotidici per bersagliare l'mrn della huntingtina
WO2017132669A1 (en) * 2016-01-31 2017-08-03 University Of Massachusetts Branched oligonucleotides
US20200385737A1 (en) * 2019-03-29 2020-12-10 University Of Massachusetts OLIGONUCLEOTIDE-BASED MODULATION OF C9orf72
WO2021026490A1 (en) * 2019-08-08 2021-02-11 Mpeg La, L.L.C. Cns targeting with multimeric oligonucleotides
MX2022001710A (es) * 2019-08-09 2022-05-10 Univ Massachusetts Oligonucleótidos modificados químicamente dirigidos a los snp.

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