JPWO2022114122A5 - - Google Patents

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Publication number
JPWO2022114122A5
JPWO2022114122A5 JP2022565447A JP2022565447A JPWO2022114122A5 JP WO2022114122 A5 JPWO2022114122 A5 JP WO2022114122A5 JP 2022565447 A JP2022565447 A JP 2022565447A JP 2022565447 A JP2022565447 A JP 2022565447A JP WO2022114122 A5 JPWO2022114122 A5 JP WO2022114122A5
Authority
JP
Japan
Prior art keywords
hydroxymethyl
tetrahydroquinoline
fluoro
hydroxy
carboxamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2022565447A
Other languages
English (en)
Japanese (ja)
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JPWO2022114122A1 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2021/043375 external-priority patent/WO2022114122A1/ja
Publication of JPWO2022114122A1 publication Critical patent/JPWO2022114122A1/ja
Publication of JPWO2022114122A5 publication Critical patent/JPWO2022114122A5/ja
Withdrawn legal-status Critical Current

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JP2022565447A 2020-11-30 2021-11-26 Withdrawn JPWO2022114122A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020199206 2020-11-30
PCT/JP2021/043375 WO2022114122A1 (ja) 2020-11-30 2021-11-26 神経障害性疼痛を緩和させるための医薬

Publications (2)

Publication Number Publication Date
JPWO2022114122A1 JPWO2022114122A1 (https=) 2022-06-02
JPWO2022114122A5 true JPWO2022114122A5 (https=) 2023-08-16

Family

ID=81755628

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022565447A Withdrawn JPWO2022114122A1 (https=) 2020-11-30 2021-11-26

Country Status (11)

Country Link
US (1) US20240009180A1 (https=)
EP (1) EP4272758A4 (https=)
JP (1) JPWO2022114122A1 (https=)
KR (1) KR20230096055A (https=)
CN (1) CN116782901A (https=)
AU (1) AU2021389409A1 (https=)
CA (1) CA3198258A1 (https=)
IL (1) IL302972A (https=)
MX (1) MX2023006289A (https=)
TW (1) TW202237111A (https=)
WO (1) WO2022114122A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121159455A (zh) * 2024-06-18 2025-12-19 武汉人福创新药物研发中心有限公司 氨基酯类化合物及其作为p2x7拮抗剂的用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013269606B2 (en) 2012-06-01 2018-05-17 Ablynx N.V. P2X7 receptor antagonists and agonists
JP6301920B2 (ja) 2013-05-27 2018-03-28 国立大学法人 岡山大学 疼痛治療薬
US11077100B2 (en) * 2017-03-13 2021-08-03 Raqualia Pharma Inc. Tetrahydroquinoline derivatives as P2X7 receptor antagonists
EP3398941A1 (en) 2017-05-03 2018-11-07 AXXAM S.p.A. Heterocyclic p2x7 antagonists
JP7311944B2 (ja) 2018-04-16 2023-07-20 塩野義製薬株式会社 二環性含窒素複素環誘導体を含有する医薬組成物
JP2019182806A (ja) 2018-04-16 2019-10-24 塩野義製薬株式会社 二環性複素環誘導体およびそれらを含有する医薬組成物

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