JPWO2022109307A5 - - Google Patents

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Publication number
JPWO2022109307A5
JPWO2022109307A5 JP2023530278A JP2023530278A JPWO2022109307A5 JP WO2022109307 A5 JPWO2022109307 A5 JP WO2022109307A5 JP 2023530278 A JP2023530278 A JP 2023530278A JP 2023530278 A JP2023530278 A JP 2023530278A JP WO2022109307 A5 JPWO2022109307 A5 JP WO2022109307A5
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JP
Japan
Prior art keywords
days
pharmaceutical composition
use according
compound
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023530278A
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English (en)
Japanese (ja)
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JP2024500288A (ja
JP2024500288A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/060151 external-priority patent/WO2022109307A1/en
Publication of JP2024500288A publication Critical patent/JP2024500288A/ja
Publication of JPWO2022109307A5 publication Critical patent/JPWO2022109307A5/ja
Publication of JP2024500288A5 publication Critical patent/JP2024500288A5/ja
Pending legal-status Critical Current

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JP2023530278A 2020-11-19 2021-11-19 Kras変異癌の治療 Pending JP2024500288A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202063115969P 2020-11-19 2020-11-19
US63/115,969 2020-11-19
US202163154652P 2021-02-26 2021-02-26
US63/154,652 2021-02-26
US202163158849P 2021-03-09 2021-03-09
US63/158,849 2021-03-09
US202163173361P 2021-04-10 2021-04-10
US63/173,361 2021-04-10
PCT/US2021/060151 WO2022109307A1 (en) 2020-11-19 2021-11-19 Treatment of kras mutant cancers

Publications (3)

Publication Number Publication Date
JP2024500288A JP2024500288A (ja) 2024-01-09
JPWO2022109307A5 true JPWO2022109307A5 (https=) 2024-11-27
JP2024500288A5 JP2024500288A5 (https=) 2024-11-27

Family

ID=81709695

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023530278A Pending JP2024500288A (ja) 2020-11-19 2021-11-19 Kras変異癌の治療

Country Status (9)

Country Link
US (1) US20240016781A1 (https=)
EP (1) EP4247806A4 (https=)
JP (1) JP2024500288A (https=)
KR (1) KR20230148144A (https=)
AU (1) AU2021381423A1 (https=)
CA (1) CA3198938A1 (https=)
IL (1) IL302925A (https=)
MX (1) MX2023005806A (https=)
WO (1) WO2022109307A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2022271290A1 (en) 2021-05-07 2023-11-23 Kymera Therapeutics, Inc. Cdk2 degraders and uses thereof
EP4376839A4 (en) * 2021-07-26 2025-10-15 Vincerx Pharma Inc SELECTIVE CDK9 INHIBITOR FOR THE TREATMENT OF RAS MUTANT CANCER
CN119522225A (zh) 2022-09-29 2025-02-25 广州嘉越医药科技有限公司 大环衍生物及其应用
IL319991A (en) * 2022-10-03 2025-06-01 Prelude Therapeutics Inc Cancer treatment using combinations of SMARCA2 inhibitors and KRAS-targeted therapies
WO2024173833A1 (en) * 2023-02-16 2024-08-22 Mei Pharma, Inc. Combination of a cdk inhibitor and a flt3 inhibitor for the treatment of cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8563596B2 (en) * 2006-06-21 2013-10-22 Piramal Enterprises Limited Enantiomerically pure compounds for the treatment of proliferative disorders
CN104220066A (zh) * 2010-11-19 2014-12-17 皮拉马尔企业有限公司 紫杉醇和cdk抑制剂药物组合物
CN105530931B (zh) * 2013-07-12 2019-11-08 皮拉马尔企业有限公司 用于治疗黑素瘤的药物组合
RU2726367C2 (ru) * 2016-03-28 2020-07-13 Пресидж Байосайенсиз, Инк. Фармацевтические комбинации для лечения злокачественной опухоли
US20220175750A1 (en) * 2018-04-23 2022-06-09 The Regents Of The University Of California Sustained release formulation for local delivery of cdk9 inhibitors
WO2020046966A1 (en) * 2018-08-27 2020-03-05 Kura Oncology, Inc. Treatment of adenocarcinomas with mapk pathway inhibitors
JP7377679B2 (ja) * 2018-11-19 2023-11-10 アムジエン・インコーポレーテツド がん治療のためのkrasg12c阻害剤及び1種以上の薬学的に活性な追加の薬剤を含む併用療法
AU2020271908B2 (en) * 2019-04-11 2025-12-04 Mei Pharma, Inc. Voruciclib poly morphs and methods of making and using thereof
CA3148504A1 (en) * 2019-08-08 2021-02-11 Institute For Cancer Research D/B/A/ The Research Institute Of Fox Chase Cancer Center Combination therapy for treatment of cancer
WO2022217133A1 (en) * 2021-04-10 2022-10-13 Mei Pharma, Inc. Voruciclib dosing regimens and methods of treatment including the same

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