JPWO2022080249A5 - - Google Patents
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- Publication number
- JPWO2022080249A5 JPWO2022080249A5 JP2022556908A JP2022556908A JPWO2022080249A5 JP WO2022080249 A5 JPWO2022080249 A5 JP WO2022080249A5 JP 2022556908 A JP2022556908 A JP 2022556908A JP 2022556908 A JP2022556908 A JP 2022556908A JP WO2022080249 A5 JPWO2022080249 A5 JP WO2022080249A5
- Authority
- JP
- Japan
- Prior art keywords
- serine
- agent
- preventive
- inflammatory bowel
- bowel disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003795 chemical substances by application Substances 0.000 claims 10
- MTCFGRXMJLQNBG-UWTATZPHSA-N D-Serine Chemical compound OC[C@@H](N)C(O)=O MTCFGRXMJLQNBG-UWTATZPHSA-N 0.000 claims 8
- 229930195711 D-Serine Natural products 0.000 claims 8
- 230000003449 preventive effect Effects 0.000 claims 6
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 5
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims 2
- 150000008569 D-serines Chemical class 0.000 claims 2
- 210000004347 intestinal mucosa Anatomy 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 206010012735 Diarrhoea Diseases 0.000 claims 1
- 108010016626 Dipeptides Proteins 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 208000027503 bloody stool Diseases 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 208000035861 hematochezia Diseases 0.000 claims 1
- 230000008595 infiltration Effects 0.000 claims 1
- 238000001764 infiltration Methods 0.000 claims 1
- 229940125700 inflammatory bowel disease agent Drugs 0.000 claims 1
- 210000000265 leukocyte Anatomy 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 229940127557 pharmaceutical product Drugs 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 229960001153 serine Drugs 0.000 claims 1
- 235000021419 vinegar Nutrition 0.000 claims 1
- 239000000052 vinegar Substances 0.000 claims 1
- 230000004580 weight loss Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020171646 | 2020-10-12 | ||
| PCT/JP2021/037311 WO2022080249A1 (ja) | 2020-10-12 | 2021-10-08 | 炎症性腸疾患の予防又は改善剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2022080249A1 JPWO2022080249A1 (https=) | 2022-04-21 |
| JPWO2022080249A5 true JPWO2022080249A5 (https=) | 2024-10-30 |
Family
ID=81208102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022556908A Pending JPWO2022080249A1 (https=) | 2020-10-12 | 2021-10-08 |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JPWO2022080249A1 (https=) |
| WO (1) | WO2022080249A1 (https=) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4378088B2 (ja) * | 2002-02-22 | 2009-12-02 | 日本臓器製薬株式会社 | ピペラジン誘導体 |
| US20100184708A1 (en) * | 2007-09-11 | 2010-07-22 | Dorian Bevec | Use of gly-pro-glu-oh (gpe) as a therapeutic agent |
| JP2012214451A (ja) * | 2011-03-25 | 2012-11-08 | En Otsuka Pharmaceutical Co Ltd | 炎症性疾患用アミノ酸組成物 |
| US20210283082A1 (en) * | 2018-06-07 | 2021-09-16 | National University Corporation Kanazawa University | Pharmaceutical composition for prevention or treatment of kidney damage |
| JP7467138B2 (ja) * | 2020-01-30 | 2024-04-15 | 株式会社 資生堂 | 腸管バリア改善剤 |
| US20230063703A1 (en) * | 2020-02-18 | 2023-03-02 | Keio University | Drug and food for treating and/or preventing enteritis and/or hepatitis |
-
2021
- 2021-10-08 JP JP2022556908A patent/JPWO2022080249A1/ja active Pending
- 2021-10-08 WO PCT/JP2021/037311 patent/WO2022080249A1/ja not_active Ceased
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