JPWO2022051749A5 - - Google Patents
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- Publication number
- JPWO2022051749A5 JPWO2022051749A5 JP2023514397A JP2023514397A JPWO2022051749A5 JP WO2022051749 A5 JPWO2022051749 A5 JP WO2022051749A5 JP 2023514397 A JP2023514397 A JP 2023514397A JP 2023514397 A JP2023514397 A JP 2023514397A JP WO2022051749 A5 JPWO2022051749 A5 JP WO2022051749A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- population
- culture
- engineered
- interleukin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063073671P | 2020-09-02 | 2020-09-02 | |
| US63/073,671 | 2020-09-02 | ||
| PCT/US2021/071330 WO2022051749A1 (en) | 2020-09-02 | 2021-08-31 | Enhanced expansion and cytotoxicity of engineered natural killer cells and uses thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2023539361A JP2023539361A (ja) | 2023-09-13 |
| JPWO2022051749A5 true JPWO2022051749A5 (https=) | 2024-09-10 |
| JP2023539361A5 JP2023539361A5 (https=) | 2024-09-10 |
| JP7824934B2 JP7824934B2 (ja) | 2026-03-05 |
Family
ID=80492150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023514397A Active JP7824934B2 (ja) | 2020-09-02 | 2021-08-31 | 操作されたナチュラルキラー細胞の増殖および細胞毒性の増強およびその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230265390A1 (https=) |
| EP (1) | EP4204560A4 (https=) |
| JP (1) | JP7824934B2 (https=) |
| KR (1) | KR20230058167A (https=) |
| CN (1) | CN116568805A (https=) |
| AU (1) | AU2021337000A1 (https=) |
| CA (1) | CA3191047A1 (https=) |
| IL (1) | IL300903A (https=) |
| WO (1) | WO2022051749A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015259877B2 (en) | 2014-05-15 | 2021-02-25 | National University Of Singapore | Modified natural killer cells and uses thereof |
| KR102660336B1 (ko) | 2017-03-27 | 2024-04-26 | 내셔널 유니버시티 오브 싱가포르 | 절단된 nkg2d 키메라 수용체 및 자연 살해 세포 면역요법에서의 그의 용도 |
| AU2019219454A1 (en) | 2018-02-09 | 2020-08-27 | National University Of Singapore | Activating chimeric receptors and uses thereof in natural killer cell immunotherapy |
| CN112055717B (zh) | 2018-04-02 | 2024-04-26 | 新加坡国立大学 | 用在免疫细胞中表达的膜结合抗细胞因子非信号传导粘合剂中和人细胞因子 |
| EP3844186A4 (en) | 2018-08-29 | 2022-08-17 | National University of Singapore | METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS |
| US12590148B2 (en) | 2018-11-26 | 2026-03-31 | Nkarta, Inc. | Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy |
| AU2020232691B2 (en) | 2019-03-05 | 2023-06-29 | Nkarta, Inc. | CD19-directed chimeric antigen receptors and uses thereof in immunotherapy |
| EP4649139A1 (en) * | 2023-02-01 | 2025-11-19 | Nkarta, Inc. | Methods for expanding immune cells and related compositions and uses thereof |
| KR102669705B1 (ko) * | 2023-02-24 | 2024-06-10 | 이엔셀 주식회사 | 제대혈 유래 자연 살해 세포의 확장배양방법 |
| KR20240175366A (ko) * | 2023-06-12 | 2024-12-20 | 한국화학연구원 | Nk 세포의 증식 촉진 또는 활성화용 조성물 및 그의 용도 |
| KR20250153112A (ko) * | 2024-04-16 | 2025-10-24 | 주식회사 유씨아이테라퓨틱스 | 자연살해세포의 증폭 및 형질 도입 효율 증진용 피더 세포 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109844099B (zh) * | 2016-07-25 | 2024-01-02 | 美国政府(由卫生和人类服务部的部长所代表) | 产生经修饰的自然杀伤细胞的方法及使用方法 |
| US10300089B2 (en) * | 2016-11-08 | 2019-05-28 | University Of Central Florida Research Foundation, Inc. | Methods for high scale therapeutic production of memory NK cells |
| KR102746901B1 (ko) * | 2017-03-03 | 2024-12-26 | 옵시디안 테라퓨틱스, 인크. | Cd19 조성물 및 면역요법을 위한 방법 |
| MX2019011570A (es) * | 2017-03-27 | 2019-11-18 | Nat Univ Singapore | Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales. |
| JP7273421B2 (ja) * | 2018-02-21 | 2023-05-15 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用 |
| US12590148B2 (en) * | 2018-11-26 | 2026-03-31 | Nkarta, Inc. | Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy |
| MX2022001255A (es) * | 2019-07-31 | 2022-05-10 | Nkarta Inc | Metodos y composiciones para la expansion y la citotoxicidad mejoradas de las celulas asesinas naturales. |
-
2021
- 2021-08-31 CN CN202180072917.0A patent/CN116568805A/zh active Pending
- 2021-08-31 KR KR1020237011188A patent/KR20230058167A/ko active Pending
- 2021-08-31 CA CA3191047A patent/CA3191047A1/en active Pending
- 2021-08-31 JP JP2023514397A patent/JP7824934B2/ja active Active
- 2021-08-31 EP EP21865294.9A patent/EP4204560A4/en active Pending
- 2021-08-31 IL IL300903A patent/IL300903A/en unknown
- 2021-08-31 US US18/024,012 patent/US20230265390A1/en active Pending
- 2021-08-31 WO PCT/US2021/071330 patent/WO2022051749A1/en not_active Ceased
- 2021-08-31 AU AU2021337000A patent/AU2021337000A1/en active Pending
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