|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
|
US5763263A
(en)
|
1995-11-27 |
1998-06-09 |
Dehlinger; Peter J. |
Method and apparatus for producing position addressable combinatorial libraries
|
|
WO2008076415A1
(en)
|
2006-12-14 |
2008-06-26 |
Exelixis, Inc. |
Methods of using mek inhibitors
|
|
JP5454943B2
(ja)
|
2007-04-12 |
2014-03-26 |
ジョイアント ファーマスーティカルズ、インク． |
抗癌剤として有用なｓｍａｃ模倣二量体及び三量体
|
|
WO2009070689A1
(en)
|
2007-11-29 |
2009-06-04 |
Enanta Pharmaceuticals, Inc. |
Bicyclic, c5-substituted proline derivatives as inhibitors of the hepatitis c virus ns3 protease
|
|
US8871794B2
(en)
|
2008-06-04 |
2014-10-28 |
Board Of Regents, The University Of Texas System |
Small-molecule agonists for type-2 orexin receptor
|
|
US20100074863A1
(en)
|
2008-09-17 |
2010-03-25 |
Yat Sun Or |
Anti-infective pyrrolidine derivatives and analogs
|
|
EP2275421A1
(en)
*
|
2009-07-15 |
2011-01-19 |
Rottapharm S.p.A. |
Spiro amino compounds suitable for the treatment of inter alia sleep disorders and drug addiction
|
|
WO2011073376A1
(en)
|
2009-12-18 |
2011-06-23 |
Euroscreen S.A. |
Pyrrolidine or thiazolidine carboxylic acid derivatives, pharmaceutical composition and methods for use in treating metabolic disordersas as agonists of g- protein coupled receptor 43 (gpr43)
|
|
GB201103526D0
(en)
|
2011-03-02 |
2011-04-13 |
Summit Corp Plc |
Selective glycosidase inhibitors and uses thereof
|
|
US9309236B2
(en)
|
2011-10-05 |
2016-04-12 |
The Board Of Trustees Of The Leland Stanford Junior University |
PI-kinase inhibitors with broad spectrum anti-infective activity
|
|
ITMI20112329A1
(it)
|
2011-12-21 |
2013-06-22 |
Rottapharm Spa |
Nuovi derivati spiro amminici
|
|
CN105916500A
(zh)
|
2013-11-27 |
2016-08-31 |
欧洲筛选有限公司 |
用于治疗炎性疾病的化合物、药物组合物和方法
|
|
SG11201700851WA
(en)
|
2014-08-05 |
2017-03-30 |
Alios Biopharma Inc |
Combination therapy for treating a paramyxovirus
|
|
WO2016021629A1
(ja)
|
2014-08-06 |
2016-02-11 |
塩野義製薬株式会社 |
ＴｒｋＡ阻害活性を有する複素環および炭素環誘導体
|
|
LT3984994T
(lt)
|
2016-02-04 |
2024-10-10 |
Takeda Pharmaceutical Company Limited |
Pakeistas piperidino junginys kaip 2 tipo oreksino agonistas narkolepsijai gydyti
|
|
JP7012703B2
(ja)
|
2017-03-08 |
2022-02-14 |
武田薬品工業株式会社 |
置換ピロリジン化合物およびその用途
|
|
US11059780B2
(en)
|
2017-03-08 |
2021-07-13 |
Takeda Pharmaceutical Company Limited |
Substituted pyrrolidine compound and use thereof
|
|
WO2019027069A1
(ko)
|
2017-08-03 |
2019-02-07 |
(주)상아프론테크 |
연료전지 전해질 강화막 및 이의 제조방법
|
|
US10428023B2
(en)
|
2017-08-03 |
2019-10-01 |
Takeda Pharmaceutical Company Limited |
Heterocyclic compound and use thereof
|
|
JP7339250B2
(ja)
|
2018-06-29 |
2023-09-05 |
武田薬品工業株式会社 |
複素環化合物およびその用途
|
|
US12071434B2
(en)
|
2018-12-12 |
2024-08-27 |
Takeda Pharmaceutical Company Limited |
Heterocyclic compound
|
|
EP3896060B1
(en)
|
2018-12-12 |
2023-08-16 |
Takeda Pharmaceutical Company Limited |
Heterocyclic compound
|
|
JP7253640B2
(ja)
*
|
2019-01-31 |
2023-04-06 |
武田薬品工業株式会社 |
複素環化合物およびその用途
|
|
US11098029B2
(en)
|
2019-02-13 |
2021-08-24 |
Merck Sharp & Dohme Corp. |
5-alkyl pyrrolidine orexin receptor agonists
|
|
AU2020346456A1
(en)
|
2019-09-13 |
2022-04-14 |
Takeda Pharmaceutical Company Limited |
TAK-925 for use in treating narcolepsy
|
|
KR20220062361A
(ko)
|
2019-09-13 |
2022-05-16 |
다케다 야쿠힌 고교 가부시키가이샤 |
과도한 졸림의 치료를 위한 오렉신 2 수용체 효능제의 용도
|
|
JPWO2021065893A1
(https=)
|
2019-09-30 |
2021-04-08 |
|
|
|
EP4065585B1
(en)
|
2019-11-25 |
2025-08-20 |
Alkermes, Inc. |
Substituted macrocyclic compounds and related methods of treatment
|
|
ES3061443T3
(en)
|
2019-11-27 |
2026-04-01 |
Sumitomo Pharma Co Ltd |
Cycloalkyl urea derivative
|
|
US20210200298A1
(en)
|
2019-12-30 |
2021-07-01 |
Advanced Micro Devices, Inc. |
Long-idle state system and method
|
|
JP7811578B2
(ja)
|
2020-09-03 |
2026-02-05 |
センテッサ ファーマシューティカルズ （ユーケー） リミテッド |
中環状または大環状ベンジル置換複素環誘導体およびオレキシン－２受容体アゴニストとしてのそれらの使用
|
|
CN116583502A
(zh)
|
2020-09-03 |
2023-08-11 |
欧瑞夏治疗有限公司 |
二环-杂环衍生物及其作为食欲素-2受体激动剂的用途
|
|
WO2022207935A1
(en)
|
2021-04-02 |
2022-10-06 |
Orexia Therapeutics Limited |
2-(3-ethynylbenzyl)-substituted heterocycle derivatives as orexin-2 agonists
|
|
WO2023017180A1
(en)
|
2021-08-13 |
2023-02-16 |
Orexia Therapeutics Limited |
Peptide derivatives and related uses as orexin agonists
|
|
JP2025507852A
(ja)
|
2022-03-01 |
2025-03-21 |
センテッサ ファーマシューティカルズ （ユーケー） リミテッド |
中環状または大環状ベンジル置換複素環誘導体および関連の使用
|
|
EP4486445A1
(en)
|
2022-03-01 |
2025-01-08 |
Centessa Pharmaceuticals (UK) Limited |
Bicyclic-heterocycle derivatives and related uses
|