JPWO2022042673A5 - - Google Patents
Info
- Publication number
- JPWO2022042673A5 JPWO2022042673A5 JP2023512724A JP2023512724A JPWO2022042673A5 JP WO2022042673 A5 JPWO2022042673 A5 JP WO2022042673A5 JP 2023512724 A JP2023512724 A JP 2023512724A JP 2023512724 A JP2023512724 A JP 2023512724A JP WO2022042673 A5 JPWO2022042673 A5 JP WO2022042673A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- amino acid
- acid sequence
- light chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010882873 | 2020-08-28 | ||
| CN202010882873.5 | 2020-08-28 | ||
| CN202110958128 | 2021-08-20 | ||
| CN202110958128.9 | 2021-08-20 | ||
| PCT/CN2021/114911 WO2022042673A1 (zh) | 2020-08-28 | 2021-08-27 | 用于降低异源多肽末端异质性的信号肽 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2023539581A JP2023539581A (ja) | 2023-09-15 |
| JP2023539581A5 JP2023539581A5 (https=) | 2025-10-30 |
| JPWO2022042673A5 true JPWO2022042673A5 (https=) | 2025-10-30 |
| JP7817241B2 JP7817241B2 (ja) | 2026-02-18 |
Family
ID=80352714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023512724A Active JP7817241B2 (ja) | 2020-08-28 | 2021-08-27 | ヘテロポリペプチドの末端異質性を低減するためのシグナルペプチド |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230312725A1 (https=) |
| EP (1) | EP4206222A4 (https=) |
| JP (1) | JP7817241B2 (https=) |
| CN (1) | CN116234814A (https=) |
| CA (1) | CA3191184A1 (https=) |
| TW (1) | TWI889889B (https=) |
| WO (1) | WO2022042673A1 (https=) |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2182498A1 (en) * | 1994-02-01 | 1995-08-10 | William J. Larochelle | Fusion proteins that include antibody and nonantibody portions |
| IL140110A0 (en) * | 2000-12-05 | 2002-02-10 | Applied Research Systems | Improvement of homogeneity and secretion of recombinant proteins in mammalian systems |
| AU2003237332A1 (en) * | 2002-06-03 | 2003-12-19 | Centocor, Inc. | Anti-relp fusion antibodies, compositions, methods and uses |
| AR047440A1 (es) * | 2004-01-21 | 2006-01-18 | Novozymes As | Produccion de un anticuerpo monoclonal en un hongo heterocarion o una celula huesped fungal |
| CN101375161A (zh) * | 2006-01-27 | 2009-02-25 | 默克公司 | 靶定金黄色葡萄球菌ORF0657n的抗原结合蛋白 |
| CN101460520B (zh) * | 2006-06-02 | 2012-12-26 | Aveo制药公司 | 肝细胞生长因子(hgf)的结合蛋白质 |
| AR061171A1 (es) | 2006-06-02 | 2008-08-06 | Aveo Pharmaceuticals Inc | Proteinas de union al factor de crecimiento de hepatocitos (fch) |
| AU2008318320B2 (en) | 2007-11-02 | 2014-11-27 | The Johns Hopkins University | Multitype HPV peptide compositions and methods for treatment or prevention of human papillomavirus infection |
| EP2906599B1 (en) * | 2012-10-12 | 2019-07-17 | Agency For Science, Technology And Research | Optimised heavy chain and light chain signal peptides for the production of recombinant antibody therapeutics |
| WO2016165762A1 (en) | 2015-04-15 | 2016-10-20 | Ganymed Pharmaceuticals Ag | Drug conjugates comprising antibodies against claudin 18.2 |
| MX2021011489A (es) * | 2019-04-01 | 2021-10-22 | Jiangsu Hengrui Medicine Co | Anticuerpo anti-claudina 18.2 y utilizacion del mismo. |
| CN114341184B (zh) | 2020-02-10 | 2023-04-04 | 北京拓界生物医药科技有限公司 | 抗FcRn抗体、其抗原结合片段及其医药用途 |
| CN113484526B (zh) * | 2021-08-11 | 2024-08-23 | 上海迈晋生物医药科技有限公司 | 一种抗FcRn抗体或其抗原结合片段生物学活性的检测方法 |
-
2021
- 2021-08-27 WO PCT/CN2021/114911 patent/WO2022042673A1/zh not_active Ceased
- 2021-08-27 EP EP21860507.9A patent/EP4206222A4/en active Pending
- 2021-08-27 CN CN202180050556.XA patent/CN116234814A/zh active Pending
- 2021-08-27 TW TW110131910A patent/TWI889889B/zh active
- 2021-08-27 US US18/023,301 patent/US20230312725A1/en active Pending
- 2021-08-27 JP JP2023512724A patent/JP7817241B2/ja active Active
- 2021-08-27 CA CA3191184A patent/CA3191184A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2020213579B2 (en) | Anti-PD-1 antibody, antigen-binding fragment thereof and pharmaceutical use thereof | |
| EP4389226A2 (en) | Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof | |
| EP3882268A1 (en) | Anti-cd73 antibody, antigen-binding fragment thereof and application thereof | |
| JPWO2019173291A5 (https=) | ||
| TWI373475B (en) | Recombinant triplex scaffold-based polypeptides | |
| CN116829194A (zh) | 用于工程化细胞疗法的靶向细胞因子构建体 | |
| JP2013517799A (ja) | Ｃｄ１２７結合タンパク質 | |
| US20230348556A1 (en) | Artificial immunosurveillance chimeric antigen receptor and cells expressing the same | |
| JP2021506275A5 (https=) | ||
| WO2018199595A1 (ko) | 4-1bbl 변이체 및 이를 포함하는 융합 단백질 | |
| TW202317624A (zh) | 結合cldn18.2及cd3之雙特異性結合劑 | |
| JPWO2021173995A5 (https=) | ||
| WO2020172643A2 (en) | Artificial immunosurveillance chimeric antigen receptor (ai-car) and cells expressing the same | |
| TW202311295A (zh) | 一種抗原結合分子 | |
| JP2016528896A (ja) | 真核細胞においてポリペプチドを発現させるための発現構築物及び方法 | |
| JPWO2022042673A5 (https=) | ||
| JPWO2022216514A5 (https=) | ||
| CA2557055A1 (en) | Peptides for stimulating an immune response against melanoma | |
| TW202206099A (zh) | 藉由併用抗人類Fn14抗體及免疫檢查點抑制劑預防或治療癌症之醫藥組合物及方法 | |
| CN120040594B (zh) | 一种靶向flt3基因编辑通用型car-t细胞的制备方法和应用 | |
| CN115551892A (zh) | 用于耗竭调节性t细胞的双特异性融合蛋白 | |
| US20140273093A1 (en) | Methods of producing antibodies in yeast | |
| CN111116749B (zh) | 重组的人源化gpc3抗体及其制备和应用 | |
| AU2022348521A1 (en) | Methods of controlling antibody heterogeneity | |
| WO2022221028A1 (en) | Taci/bcma dual binding molecules |