|
US4603209A
(en)
|
1984-09-07 |
1986-07-29 |
The Regents Of The University Of California |
Fluorescent indicator dyes for calcium ions
|
|
US4714763A
(en)
|
1985-07-11 |
1987-12-22 |
Viomedics Inc. |
Novel oxazine-ureas and thiazine urea chromophors as fluorescent labels
|
|
US4812409A
(en)
|
1986-01-31 |
1989-03-14 |
Eastman Kodak Company |
Hydrolyzable fluorescent substrates and analytical determinations using same
|
|
US5268486A
(en)
|
1986-04-18 |
1993-12-07 |
Carnegie-Mellon Unversity |
Method for labeling and detecting materials employing arylsulfonate cyanine dyes
|
|
US5627027A
(en)
|
1986-04-18 |
1997-05-06 |
Carnegie Mellon University |
Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
|
|
US5569587A
(en)
|
1986-04-18 |
1996-10-29 |
Carnegie Mellon University |
Method for labeling and detecting materials employing luminescent arysulfonate cyanine dyes
|
|
US4810636A
(en)
|
1986-12-09 |
1989-03-07 |
Miles Inc. |
Chromogenic acridinone enzyme substrates
|
|
US4774339A
(en)
|
1987-08-10 |
1988-09-27 |
Molecular Probes, Inc. |
Chemically reactive dipyrrometheneboron difluoride dyes
|
|
US4849362A
(en)
|
1988-05-19 |
1989-07-18 |
Smithkline Beckman Corporation |
Fluorescent intracellular calcium indicators
|
|
US4981977A
(en)
|
1989-06-09 |
1991-01-01 |
Carnegie-Mellon University |
Intermediate for and fluorescent cyanine dyes containing carboxylic acid groups
|
|
US5132432A
(en)
|
1989-09-22 |
1992-07-21 |
Molecular Probes, Inc. |
Chemically reactive pyrenyloxy sulfonic acid dyes
|
|
US5274113A
(en)
|
1991-11-01 |
1993-12-28 |
Molecular Probes, Inc. |
Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugates
|
|
US5227487A
(en)
|
1990-04-16 |
1993-07-13 |
Molecular Probes, Inc. |
Certain tricyclic and pentacyclic-hetero nitrogen rhodol dyes
|
|
US5433896A
(en)
|
1994-05-20 |
1995-07-18 |
Molecular Probes, Inc. |
Dibenzopyrrometheneboron difluoride dyes
|
|
US5459276A
(en)
|
1994-05-20 |
1995-10-17 |
Molecular Probes, Inc. |
Benzazolylcoumarin-based ion indicators for heavy metals
|
|
US5501980A
(en)
|
1994-05-20 |
1996-03-26 |
Molecular Probes, Inc. |
Benzazolylcoumarin-based ion indicators
|
|
US5248782A
(en)
|
1990-12-18 |
1993-09-28 |
Molecular Probes, Inc. |
Long wavelength heteroaryl-substituted dipyrrometheneboron difluoride dyes
|
|
US5451343A
(en)
|
1991-05-20 |
1995-09-19 |
Spectra Group Limited, Inc. |
Fluorone and pyronin y derivatives
|
|
US5187288A
(en)
|
1991-05-22 |
1993-02-16 |
Molecular Probes, Inc. |
Ethenyl-substituted dipyrrometheneboron difluoride dyes and their synthesis
|
|
US5242805A
(en)
|
1991-08-23 |
1993-09-07 |
Molecular Probes, Inc. |
Long wavelength lipophilic fluorogenic glycosidase substrates
|
|
US5808044A
(en)
|
1993-01-22 |
1998-09-15 |
Pharmacia Biotech Inc. |
Indocarbocyanine and benzindocarbocyanine phosphoramidites
|
|
US6127134A
(en)
|
1995-04-20 |
2000-10-03 |
Carnegie Mellon University |
Difference gel electrophoresis using matched multiple dyes
|
|
US6008373A
(en)
|
1995-06-07 |
1999-12-28 |
Carnegie Mellon University |
Fluorescent labeling complexes with large stokes shift formed by coupling together cyanine and other fluorochromes capable of resonance energy transfer
|
|
US5798276A
(en)
|
1995-06-07 |
1998-08-25 |
Molecular Probes, Inc. |
Reactive derivatives of sulforhodamine 101 with enhanced hydrolytic stability
|
|
US6004536A
(en)
|
1995-11-14 |
1999-12-21 |
Molecular Probes, Inc. |
Lipophilic cyanine dyes with enchanced aqueous solubilty
|
|
US6162931A
(en)
|
1996-04-12 |
2000-12-19 |
Molecular Probes, Inc. |
Fluorinated xanthene derivatives
|
|
JP2000508709A
(ja)
|
1996-04-19 |
2000-07-11 |
アマーシャム・ファルマシア・バイオテック・ユーケイ・リミテッド |
スクアラート染料類および蛍光配列決定法におけるそれらの使用
|
|
US5846737A
(en)
|
1996-07-26 |
1998-12-08 |
Molecular Probes, Inc. |
Conjugates of sulforhodamine fluorophores with enhanced fluorescence
|
|
US5830912A
(en)
|
1996-11-15 |
1998-11-03 |
Molecular Probes, Inc. |
Derivatives of 6,8-difluoro-7-hydroxycoumarin
|
|
US5696157A
(en)
|
1996-11-15 |
1997-12-09 |
Molecular Probes, Inc. |
Sulfonated derivatives of 7-aminocoumarin
|
|
US5877310A
(en)
|
1997-04-25 |
1999-03-02 |
Carnegie Mellon University |
Glycoconjugated fluorescent labeling reagents
|
|
AU9063398A
(en)
|
1997-09-12 |
1999-04-05 |
Exiqon A/S |
Oligonucleotide analogues
|
|
US6130101A
(en)
|
1997-09-23 |
2000-10-10 |
Molecular Probes, Inc. |
Sulfonated xanthene derivatives
|
|
US6133445A
(en)
|
1997-12-17 |
2000-10-17 |
Carnegie Mellon University |
Rigidized trimethine cyanine dyes
|
|
EP1078023B1
(en)
|
1998-04-08 |
2011-01-05 |
Corporation Luminex |
Luminescent compounds
|
|
US6002003A
(en)
|
1998-04-14 |
1999-12-14 |
Beckman Instruments, Inc. |
Cyanine dye activating group with improved coupling selectivity
|
|
JP3983404B2
(ja)
|
1999-01-13 |
2007-09-26 |
本田技研工業株式会社 |
レーダ搭載車両用ゲート
|
|
US6664047B1
(en)
|
1999-04-30 |
2003-12-16 |
Molecular Probes, Inc. |
Aza-benzazolium containing cyanine dyes
|
|
EP1065250B1
(en)
|
1999-07-02 |
2004-12-08 |
Visen Medical, Inc. |
New fluorescent cyanine labels containing a sulfamido linker arm
|
|
WO2001021624A1
(en)
|
1999-09-20 |
2001-03-29 |
Fuji Photo Film Co., Ltd. |
Compounds for fluorescence labeling
|
|
AU2001279185B2
(en)
|
2000-08-04 |
2005-07-07 |
Molecular Probes, Inc. |
Derivatives of 1,2-dihydro-7-hydroxyquinolines containing fused rings
|
|
EP1322710B2
(en)
|
2000-09-29 |
2015-02-18 |
Life Technologies Corporation |
Modified carbocyanine dyes and their conjugates
|
|
US7446202B2
(en)
|
2003-12-05 |
2008-11-04 |
Molecular Probes, Inc. |
Cyanine dye compounds
|
|
US7776529B2
(en)
|
2003-12-05 |
2010-08-17 |
Life Technologies Corporation |
Methine-substituted cyanine dye compounds
|
|
US8039642B2
(en)
|
2003-12-09 |
2011-10-18 |
Life Technologies Corporation |
Pyrenyloxysulfonic acid fluorescent agents
|
|
CN101258220A
(zh)
|
2004-09-16 |
2008-09-03 |
阿普里拉股份有限公司 |
荧光染料化合物,共轭物及其应用
|
|
JP5306811B2
(ja)
|
2005-05-11 |
2013-10-02 |
ライフ テクノロジーズ コーポレーション |
2本鎖dnaへの高い選択性を有する蛍光化学物質及びそれらの使用
|
|
CN101454315B
(zh)
|
2006-03-31 |
2016-08-17 |
应用生物系统有限责任公司 |
用于合成罗丹明-标记的寡核苷酸的试剂
|
|
US10053447B2
(en)
|
2010-12-21 |
2018-08-21 |
Pierce Biotechnology, Inc |
Fluorescent compounds
|
|
CN107326073A
(zh)
|
2010-12-29 |
2017-11-07 |
生命技术公司 |
作为荧光参考标准品的 ddao 化合物
|
|
US9249307B2
(en)
|
2011-08-16 |
2016-02-02 |
Pierce Biotechnology, Inc. |
Benzocyanine compounds
|
|
WO2013059475A1
(en)
*
|
2011-10-18 |
2013-04-25 |
Life Technologies Corporation |
Alkynyl-derivatized cap analogs, preparation and uses thereof
|
|
US9751868B2
(en)
|
2012-02-28 |
2017-09-05 |
Pierce Biotechnology, Inc. |
Benzocyanine compounds
|
|
CN104395306B
(zh)
|
2012-03-02 |
2019-04-23 |
皮尔斯生物科技有限公司 |
作为生物分子的标记染料的吲哚衍生物
|
|
US20140255312A1
(en)
|
2013-03-07 |
2014-09-11 |
Greg Hermanson |
Cyanine compounds
|
|
US20190054112A1
(en)
|
2015-09-18 |
2019-02-21 |
Moderna Therapeutics, Inc. |
Polynucleotide formulations for use in the treatment of renal diseases
|
|
ES2964690T3
(es)
|
2015-09-21 |
2024-04-09 |
Trilink Biotechnologies Llc |
Método para sintetizar ARN con caperuza 5'
|
|
US11866754B2
(en)
|
2015-10-16 |
2024-01-09 |
Modernatx, Inc. |
Trinucleotide mRNA cap analogs
|
|
CA3002912A1
(en)
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Nucleic acid vaccines for varicella zoster virus (vzv)
|
|
AU2016342049B2
(en)
|
2015-10-22 |
2023-05-18 |
Modernatx, Inc. |
Herpes simplex virus vaccine
|
|
WO2017070620A2
(en)
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Broad spectrum influenza virus vaccine
|
|
EP3364949A4
(en)
|
2015-10-22 |
2019-07-31 |
ModernaTX, Inc. |
CANCER VACCINES
|
|
MX2018004917A
(es)
|
2015-10-22 |
2019-04-01 |
Modernatx Inc |
Vacuna de virus sincitial respiratorio.
|
|
US10487105B2
(en)
|
2016-10-19 |
2019-11-26 |
Arcturus Therapeutics, Inc. |
Trinucleotide MRNA cap analogs
|
|
BR112019008481A2
(pt)
|
2016-10-26 |
2020-03-03 |
Curevac Ag |
Vacinas de mrna de nanopartículas lipídicas
|
|
US20200263231A1
(en)
|
2016-11-07 |
2020-08-20 |
Life Technologies Corporation |
Fluorogenic dyes for high sensitivity DNA detection
|
|
WO2018089851A2
(en)
|
2016-11-11 |
2018-05-17 |
Modernatx, Inc. |
Influenza vaccine
|
|
EP3551230A1
(en)
|
2016-12-08 |
2019-10-16 |
CureVac AG |
Rna for treatment or prophylaxis of a liver disease
|
|
WO2018104540A1
(en)
|
2016-12-08 |
2018-06-14 |
Curevac Ag |
Rnas for wound healing
|
|
EP3558356A2
(en)
|
2016-12-23 |
2019-10-30 |
CureVac AG |
Mers coronavirus vaccine
|
|
WO2018115525A1
(en)
|
2016-12-23 |
2018-06-28 |
Curevac Ag |
Lassa virus vaccine
|
|
EP3558355A2
(en)
|
2016-12-23 |
2019-10-30 |
CureVac AG |
Henipavirus vaccine
|
|
EP3576751A4
(en)
|
2017-02-01 |
2021-08-04 |
ModernaTX, Inc. |
RNA ANTI-CANCER VACCINES
|
|
CA3050614A1
(en)
|
2017-03-17 |
2018-09-20 |
Curevac Ag |
Rna vaccine and immune checkpoint inhibitors for combined anticancer therapy
|
|
RU2020103379A
(ru)
|
2017-07-04 |
2021-08-04 |
Куревак Аг |
Новые молекулы нуклеиновых кислот
|
|
US11602557B2
(en)
|
2017-08-22 |
2023-03-14 |
Cure Vac SE |
Bunyavirales vaccine
|
|
EP3723796A1
(en)
|
2017-12-13 |
2020-10-21 |
CureVac AG |
Flavivirus vaccine
|
|
KR20200143391A
(ko)
|
2018-03-15 |
2020-12-23 |
비온테크 알엔에이 파마슈티컬스 게엠베하 |
5'-캡-트리뉴클레오티드- 또는 고차의 올리고뉴클레오티드 화합물 및 이들의 rna 안정화, 단백질 발현 및 치료에서의 사용
|
|
WO2019193183A2
(en)
|
2018-04-05 |
2019-10-10 |
Curevac Ag |
Novel yellow fever nucleic acid molecules for vaccination
|
|
CA3091558A1
(en)
|
2018-04-17 |
2019-10-24 |
Curevac Ag |
Novel rsv rna molecules and compositions for vaccination
|
|
WO2020002525A1
(en)
|
2018-06-27 |
2020-01-02 |
Curevac Ag |
Novel lassa virus rna molecules and compositions for vaccination
|
|
PL248416B1
(pl)
*
|
2020-02-12 |
2025-12-08 |
Explorna Therapeutics Spolka Z Ograniczona Odpowiedzialnoscia |
Nowe analogi kapu końca 5’ mRNA, cząsteczka RNA je zawierająca, ich zastosowania i sposób syntezy cząsteczki RNA i peptydu
|