JPWO2021255684A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2021255684A5
JPWO2021255684A5 JP2022577503A JP2022577503A JPWO2021255684A5 JP WO2021255684 A5 JPWO2021255684 A5 JP WO2021255684A5 JP 2022577503 A JP2022577503 A JP 2022577503A JP 2022577503 A JP2022577503 A JP 2022577503A JP WO2021255684 A5 JPWO2021255684 A5 JP WO2021255684A5
Authority
JP
Japan
Prior art keywords
immunogenic composition
flexneri
glucose
glycosylation
consensus sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022577503A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023530154A5 (https=
JP2023530154A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2021/055361 external-priority patent/WO2021255684A1/en
Publication of JP2023530154A publication Critical patent/JP2023530154A/ja
Publication of JP2023530154A5 publication Critical patent/JP2023530154A5/ja
Publication of JPWO2021255684A5 publication Critical patent/JPWO2021255684A5/ja
Pending legal-status Critical Current

Links

JP2022577503A 2020-06-18 2021-06-17 赤痢菌4価(Shigella4V)バイオコンジュゲート Pending JP2023530154A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202063040844P 2020-06-18 2020-06-18
US63/040,844 2020-06-18
US202063043883P 2020-06-25 2020-06-25
EP20182138.6 2020-06-25
EP20182138 2020-06-25
US63/043,883 2020-06-25
EP20182139.4 2020-06-25
EP20182139 2020-06-25
PCT/IB2021/055361 WO2021255684A1 (en) 2020-06-18 2021-06-17 Shigella-tetravalent (shigella4v) bioconjugate

Publications (3)

Publication Number Publication Date
JP2023530154A JP2023530154A (ja) 2023-07-13
JP2023530154A5 JP2023530154A5 (https=) 2024-06-20
JPWO2021255684A5 true JPWO2021255684A5 (https=) 2024-06-20

Family

ID=76502778

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022577503A Pending JP2023530154A (ja) 2020-06-18 2021-06-17 赤痢菌4価(Shigella4V)バイオコンジュゲート

Country Status (8)

Country Link
US (1) US20230346902A1 (https=)
EP (1) EP4168040A1 (https=)
JP (1) JP2023530154A (https=)
CN (1) CN115697396A (https=)
BR (1) BR112022024294A2 (https=)
CA (1) CA3185719A1 (https=)
MX (1) MX2022016587A (https=)
WO (1) WO2021255684A1 (https=)

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
KR20090110951A (ko) 2002-03-07 2009-10-23 아이드게노쉬쉐 테흐니쉐 호흐슐레 쥬리히 원핵 숙주에서의 재조합 글리코실화 단백질 생산 방법 및 생산계
CA2607595C (en) 2005-05-11 2018-11-27 Eth Zuerich Recombinant n-glycosylated proteins from procaryotic cells
CA2646539A1 (en) 2006-03-23 2007-09-27 Novartis Ag Imidazoquinoxaline compounds as immunomodulators
CA2646891A1 (en) 2006-03-23 2007-09-27 Novartis Ag Immunopotentiating compounds
CA2671709C (en) 2006-12-13 2016-08-16 The Governors Of The University Of Alberta Methods and systems for o-glycosylating proteins
HRP20181259T1 (hr) 2008-02-20 2018-10-05 Glaxosmithkline Biologicals S.A. Biokonjugati načinjeni iz rekombinantnih n-glikoziliranih proteina iz prokariotskih stanica
EP2501406B8 (en) 2009-11-19 2018-01-24 GlaxoSmithKline Biologicals S.A. Biosynthetic system that produces immunogenic polysaccharides in prokaryotic cells
CN110423716A (zh) * 2012-10-12 2019-11-08 葛兰素史密丝克莱恩生物有限公司 宿主细胞修饰方法
CA2889767C (en) * 2012-11-07 2021-09-21 Glycovaxyn Ag Production of recombinant vaccine in e. coli by enzymatic conjugation
CN106535927B (zh) 2014-02-24 2019-09-20 葛兰素史密丝克莱恩生物有限公司 新颖多糖及其用途
ES2672045T3 (es) * 2014-07-25 2018-06-12 Biosynth S.R.L. Vacunas de productos glicoconjugados que comprenden unidades básicas de una construcción molecular que expresa múltiples epítopos incorporados para la formulación de una vacuna de amplio espectro contra infecciones debidas a bacterias enteropatógenas
CN105695497B (zh) 2014-11-27 2019-09-24 中国人民解放军军事医学科学院生物工程研究所 一种细菌多糖修饰的重组融合蛋白的制备方法及其应用
EP3310381B1 (en) * 2015-06-16 2023-06-07 GlaxoSmithKline Biologicals SA Immunogenic compositions
GB201518668D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Immunogenic Comosition

Similar Documents

Publication Publication Date Title
EP3562503B1 (en) Polypeptide-antigen conjugates with non-natural amino acids
TWI751513B (zh) E. coli O-抗原多醣生物結合物、其製備方法及其使用方法
CN106535927B (zh) 新颖多糖及其用途
TWI771663B (zh) E. coli O-抗原多醣生物結合物之製備方法、其組合物及其使用方法
CN115803087B (zh) 多价疫苗组合物及其用途
US12290563B2 (en) Production of E. coli 018 bioconjugates
Altman et al. Design and immunological properties of Helicobacter pylori glycoconjugates based on a truncated lipopolysaccharide lacking Lewis antigen and comprising an α-1, 6-glucan chain
JPWO2021255684A5 (https=)
CN101014698A (zh) 作为多种疫苗候选物的保守性内核脂多糖表位
RU2818894C1 (ru) Свободные от примеси с-полисахарида капсульные полисахариды streptococcus pneumoniae с остатком 2,5-ангидроманнозы на восстанавливающем конце
TW202434282A (zh) 多價疫苗組合物及其用途
HK40101412A (en) Methods of producing bioconjugates of e. coli o-antigen polysaccharides, compositions thereof, and methods of use thereof
EA046636B1 (ru) Способы получения биоконъюгатов полисахаридных о-антигенов e. coli, их композиции и способы их применения
EA048935B1 (ru) Поливалентные вакцинные композиции и варианты их применения
CN115697396A (zh) 志贺氏菌-四价(Shigella4V)生物缀合物
HK40058952A (en) Methods of producing bioconjugates of e. coli o-antigen polysaccharides, compositions thereof, and methods of use thereof
HK40058952B (en) Methods of producing bioconjugates of e. coli o-antigen polysaccharides, compositions thereof, and methods of use thereof
HK40015413A (en) Polypeptide-antigen conjugates with non-natural amino acids
HK40015413B (en) Polypeptide-antigen conjugates with non-natural amino acids