JPWO2021236771A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2021236771A5 JPWO2021236771A5 JP2022571280A JP2022571280A JPWO2021236771A5 JP WO2021236771 A5 JPWO2021236771 A5 JP WO2021236771A5 JP 2022571280 A JP2022571280 A JP 2022571280A JP 2022571280 A JP2022571280 A JP 2022571280A JP WO2021236771 A5 JPWO2021236771 A5 JP WO2021236771A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- nitrogen
- membered
- optionally substituted
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063028882P | 2020-05-22 | 2020-05-22 | |
| US63/028,882 | 2020-05-22 | ||
| US202163159075P | 2021-03-10 | 2021-03-10 | |
| US63/159,075 | 2021-03-10 | ||
| PCT/US2021/033159 WO2021236771A1 (en) | 2020-05-22 | 2021-05-19 | Methods and compositions for targeting pd-l1 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023527315A JP2023527315A (ja) | 2023-06-28 |
| JP2023527315A5 JP2023527315A5 (https=) | 2024-05-27 |
| JPWO2021236771A5 true JPWO2021236771A5 (https=) | 2024-05-27 |
Family
ID=78708022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022571280A Ceased JP2023527315A (ja) | 2020-05-22 | 2021-05-19 | Pd-l1を標的とするための方法及び組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11760764B2 (https=) |
| EP (1) | EP4153567A4 (https=) |
| JP (1) | JP2023527315A (https=) |
| KR (1) | KR20230030056A (https=) |
| CN (1) | CN115835907A (https=) |
| AU (1) | AU2021275118A1 (https=) |
| CA (1) | CA3182131A1 (https=) |
| TW (1) | TW202208320A (https=) |
| WO (1) | WO2021236771A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3182595A1 (en) * | 2020-06-17 | 2021-12-23 | Mingming Zhang | Immunosuppressant, and preparation method therefor and use thereof |
| JP2023539463A (ja) | 2020-08-17 | 2023-09-14 | アリゴス セラピューティクス インコーポレイテッド | Pd-l1を標的とするための方法及び組成物 |
| BR112023026747A2 (pt) * | 2021-06-18 | 2024-03-12 | Aligos Therapeutics Inc | Métodos e composições para direcionamento de pd-l1 |
| EP4363408A1 (en) * | 2021-07-02 | 2024-05-08 | Ascletics Bioscience Co., Ltd. | Heterocyclic compounds as immunomodulators of pd-l1 interactions |
| JP2024525589A (ja) | 2021-07-09 | 2024-07-12 | アリゴス セラピューティクス インコーポレイテッド | 抗ウイルス化合物 |
| JP7776616B2 (ja) * | 2021-08-17 | 2025-11-26 | アスカレシス バイオサイエンス カンパニー リミテッド | Pd-l1相互作用の免疫調節剤としての化合物 |
| WO2023043816A1 (en) | 2021-09-17 | 2023-03-23 | Aligos Therapeutics, Inc. | Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections |
| CA3240346A1 (en) | 2021-12-16 | 2023-06-22 | Aligos Therapeutics, Inc. | Methods and compositions for targeting pd-l1 |
| JP2025527595A (ja) * | 2022-11-22 | 2025-08-22 | 西安新通薬物研究股▲フン▼有限公司 | 新規二環系pd-l1阻害剤、その製造方法、及び医薬使用 |
| WO2025015063A1 (en) * | 2023-07-13 | 2025-01-16 | Aligos Therapeutics, Inc. | Methods and compositions for targeting pd-l1 |
| WO2025174835A1 (en) * | 2024-02-15 | 2025-08-21 | Aligos Therapeutics, Inc. | Methods and compositions for targeting pd-l1 |
| WO2025199281A1 (en) * | 2024-03-22 | 2025-09-25 | Aligos Therapeutics, Inc. | Methods and compositions for targeting pd-l1 |
| WO2025199273A1 (en) * | 2024-03-22 | 2025-09-25 | Aligos Therapeutics, Inc. | Methods and compositions for targeting pd-l1 |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5359084A (en) | 1993-02-18 | 1994-10-25 | General Electric Company | Method of preparing aromatic ether bisimides |
| US6638967B2 (en) | 2000-08-08 | 2003-10-28 | Ortho-Mcneil Phamraceutical, Inc. | Thiophene of furan pyrrolidine compounds |
| DE10104279A1 (de) | 2001-01-31 | 2002-08-01 | Heinz Langhals | Kompetitive Prionen-Reagenzien und ihre Anwendung in Diagnostik und Therapie |
| US7973060B2 (en) | 2005-10-13 | 2011-07-05 | Crystalgenomics, Inc. | Fab I inhibitor and process for preparing same |
| US20080186971A1 (en) | 2007-02-02 | 2008-08-07 | Tarari, Inc. | Systems and methods for processing access control lists (acls) in network switches using regular expression matching logic |
| KR101462535B1 (ko) | 2007-10-15 | 2014-11-19 | 삼성디스플레이 주식회사 | 인덴 유도체 화합물 및 이를 이용한 유기 발광 소자 |
| WO2010065668A1 (en) | 2008-12-03 | 2010-06-10 | Presidio Pharmaceuticals, Inc. | Inhibitors of hcv ns5a |
| WO2010096777A1 (en) | 2009-02-23 | 2010-08-26 | Presidio Pharmaceuticals, Inc. | Inhibitors of hcv ns5a |
| CN102422449B (zh) | 2009-05-11 | 2014-01-29 | 大日精化工业株式会社 | 有机半导体材料、有机半导体薄膜以及有机薄膜晶体管 |
| JP5765229B2 (ja) | 2009-10-05 | 2015-08-19 | 和光純薬工業株式会社 | 新規重水素化方法 |
| WO2011082400A2 (en) | 2010-01-04 | 2011-07-07 | President And Fellows Of Harvard College | Modulators of immunoinhibitory receptor pd-1, and methods of use thereof |
| KR101832171B1 (ko) | 2010-10-25 | 2018-04-16 | 삼성디스플레이 주식회사 | 축합환 화합물, 이를 포함한 유기 발광 소자 및 상기 유기 발광 소자를 포함한 평판 표시 장치 |
| JP5728921B2 (ja) | 2010-12-10 | 2015-06-03 | コニカミノルタ株式会社 | 光学フィルム、及びそれを用いた偏光板、液晶表示装置 |
| WO2012129562A2 (en) | 2011-03-24 | 2012-09-27 | The Scripps Research Institute | Compounds and methods for inducing chondrogenesis |
| ITMI20110881A1 (it) | 2011-05-18 | 2012-11-19 | E T C Srl | Materiale semiconduttore organico |
| JP6576955B2 (ja) | 2014-02-20 | 2019-09-18 | イノベーションラブ、ゲゼルシャフト、ミット、ベシュレンクテル、ハフツングInnovationlab Gmbh | 共役ポリマー |
| KR20160001537A (ko) | 2014-06-27 | 2016-01-06 | 희성소재 (주) | 피라졸계 화합물 및 이를 이용한 유기발광소자 |
| WO2016046300A1 (en) | 2014-09-24 | 2016-03-31 | Solvay Specialty Polymers Italy S.P.A. | Fluoropolymer composition |
| CN104478900B (zh) | 2014-12-02 | 2017-05-31 | 国家纳米科学中心 | 一种内酰胺类受体单元及其制备方法和用途 |
| AU2017305399A1 (en) | 2016-08-03 | 2019-01-31 | Arising International, Inc. | Symmetric or semi-symmetric compounds useful as immunomodulators |
| KR20180063710A (ko) | 2016-12-02 | 2018-06-12 | (주)피엔에이치테크 | 유기발광 화합물 및 이를 포함하는 유기전계발광소자 |
| WO2018119263A1 (en) * | 2016-12-22 | 2018-06-28 | Incyte Corporation | Heterocyclic compounds derivatives as pd-l1 internalization inducers |
| ES2874756T3 (es) * | 2016-12-22 | 2021-11-05 | Incyte Corp | Derivados de triazolo[1,5-A]piridina como inmunomoduladores |
| EP3558990B1 (en) * | 2016-12-22 | 2022-08-10 | Incyte Corporation | Tetrahydro imidazo[4,5-c]pyridine derivatives as pd-l1 internalization inducers |
| AU2017382870B2 (en) * | 2016-12-22 | 2022-03-24 | Incyte Corporation | Benzooxazole derivatives as immunomodulators |
| EP3381906A1 (en) | 2017-03-27 | 2018-10-03 | Leadiant Biosciences SA | Compounds for use as heparanase inhibitors |
| BR102018007822A2 (pt) * | 2017-04-20 | 2018-11-06 | Gilead Sciences, Inc. | composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição |
| CN110869467B (zh) | 2017-10-04 | 2022-05-10 | 株式会社艾迪科 | 组合物、固化物及固化物的制造方法 |
| CN111094256A (zh) | 2017-10-05 | 2020-05-01 | 株式会社艾迪科 | 化合物、潜在性紫外线吸收剂、组合物、固化物及固化物的制造方法 |
| CN107721805A (zh) | 2017-11-08 | 2018-02-23 | 长春海谱润斯科技有限公司 | 一种有机电致发光材料及其有机发光器件 |
| KR102591947B1 (ko) * | 2018-04-19 | 2023-10-25 | 길리애드 사이언시즈, 인코포레이티드 | Pd-1/pd-l1 억제제 |
| CN111936532B (zh) | 2018-05-08 | 2024-03-12 | 株式会社艾迪科 | 化合物、潜伏性添加剂、组合物、固化物、固化物的制造方法及组合物的制造方法 |
| CN112424185B (zh) | 2018-07-13 | 2024-05-17 | 广州丹康医药生物有限公司 | 含苯环的化合物、其制备方法及应用 |
| CN111039942B (zh) | 2018-10-12 | 2023-04-14 | 上海长森药业有限公司 | 含氮杂环类化合物,及其制备方法、药物组合物和应用 |
| WO2020126970A1 (en) | 2018-12-19 | 2020-06-25 | Solvay Specialty Polymers Usa, Llc | Method for manufacturing a three-dimensional object |
| DE102019200805A1 (de) | 2019-01-23 | 2020-07-23 | Henkel Ag & Co. Kgaa | Neue fluoreszierende Materialien auf Basis von Phthalimiden |
| CN111574504A (zh) | 2019-02-19 | 2020-08-25 | 江苏三月光电科技有限公司 | 一种基于氮杂苯和二甲酰二胺衍生物的有机化合物及其应用 |
| US20220185785A1 (en) | 2019-04-12 | 2022-06-16 | TONIX Pharmaceuticals Holding Corp | Inhibitors of cd40-cd154 binding |
| KR20220004100A (ko) | 2019-04-18 | 2022-01-11 | 하이노바 파마슈티컬스 인코포레이티드 | 안드로겐 수용체를 표적 분해하는 이중 기능성의 키메라 헤테로 고리 화합물 및 이의 용도 |
| SG11202112875UA (en) | 2019-06-20 | 2021-12-30 | Chemocentryx Inc | Compounds for treatment of pd-l1 diseases |
| CN110746344A (zh) | 2019-11-19 | 2020-02-04 | 上海天马有机发光显示技术有限公司 | 一种化合物及其应用 |
| JP2023539463A (ja) | 2020-08-17 | 2023-09-14 | アリゴス セラピューティクス インコーポレイテッド | Pd-l1を標的とするための方法及び組成物 |
| BR112023026747A2 (pt) | 2021-06-18 | 2024-03-12 | Aligos Therapeutics Inc | Métodos e composições para direcionamento de pd-l1 |
-
2021
- 2021-05-19 CA CA3182131A patent/CA3182131A1/en active Pending
- 2021-05-19 JP JP2022571280A patent/JP2023527315A/ja not_active Ceased
- 2021-05-19 EP EP21808539.7A patent/EP4153567A4/en active Pending
- 2021-05-19 WO PCT/US2021/033159 patent/WO2021236771A1/en not_active Ceased
- 2021-05-19 US US17/303,089 patent/US11760764B2/en active Active
- 2021-05-19 AU AU2021275118A patent/AU2021275118A1/en active Pending
- 2021-05-19 CN CN202180049412.2A patent/CN115835907A/zh active Pending
- 2021-05-19 KR KR1020227043982A patent/KR20230030056A/ko active Pending
- 2021-05-21 TW TW110118530A patent/TW202208320A/zh unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2021236771A5 (https=) | ||
| AU2016200538B2 (en) | Compounds and their use as BACE inhibitors | |
| JP2006507355A5 (https=) | ||
| JP6784348B2 (ja) | Sting作動化合物 | |
| JP2025525938A (ja) | Krasの阻害のための組成物及び方法 | |
| RU2378263C2 (ru) | Производные 5-фенилтиазола и их применение в качестве ингибиторов рi3 киназы | |
| JP2005538100A5 (https=) | ||
| IL295569A (en) | Tetralin and tetrahydroquinoline compounds as inhibitors of hif-2alpha | |
| JP6266659B2 (ja) | 癌の治療のための安息香酸誘導体mdm2阻害剤 | |
| JP6171003B2 (ja) | ピロロピロリジノン化合物 | |
| JPWO2020061101A5 (https=) | ||
| IL295930A (en) | Biaryl derivatives as yap/taz-tead protein-protein interaction inhibitors | |
| RU2350605C2 (ru) | Аналоги хиназолина в качестве ингибиторов рецепторных тирозинкиназ | |
| JP2001526269A5 (https=) | ||
| JP2019536779A5 (https=) | ||
| IL154350A (en) | Phenylalanine derivatives and pharmaceutical preparations containing them | |
| JP2011528034A5 (https=) | ||
| JP2005514398A5 (https=) | ||
| JP2013538802A5 (https=) | ||
| JP2003517010A5 (https=) | ||
| JP2010532386A5 (https=) | ||
| KR910009692A (ko) | 인돌 유도체 | |
| ATE357142T1 (de) | 7-aminotriazolopyrimidine zur bekämpfung von schadpilzen | |
| JP2003535128A5 (https=) | ||
| AR116474A1 (es) | DERIVADOS DEL ÁCIDO 6,7-DIHIDRO-2H-BENZOFURO[2,3-a]QUINOLIZIN-3-CARBOXÍLICO COMO AGENTES ANTIVIRALES PARA EL TRATAMIENTO O PREVENCIÓN DE UNA INFECCIÓN POR HBV |