JPWO2021231455A5 - - Google Patents
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- Publication number
- JPWO2021231455A5 JPWO2021231455A5 JP2022568686A JP2022568686A JPWO2021231455A5 JP WO2021231455 A5 JPWO2021231455 A5 JP WO2021231455A5 JP 2022568686 A JP2022568686 A JP 2022568686A JP 2022568686 A JP2022568686 A JP 2022568686A JP WO2021231455 A5 JPWO2021231455 A5 JP WO2021231455A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid molecules
- stranded dna
- cancer
- size distribution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000039446 nucleic acids Human genes 0.000 claims 25
- 108020004707 nucleic acids Proteins 0.000 claims 25
- 150000007523 nucleic acids Chemical class 0.000 claims 25
- 108020004414 DNA Proteins 0.000 claims 19
- 102000053602 DNA Human genes 0.000 claims 19
- 108020004682 Single-Stranded DNA Proteins 0.000 claims 17
- 238000000034 method Methods 0.000 claims 15
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 102000012410 DNA Ligases Human genes 0.000 claims 2
- 108010061982 DNA Ligases Proteins 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 208000003174 Brain Neoplasms Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 206010014733 Endometrial cancer Diseases 0.000 claims 1
- 206010014759 Endometrial neoplasm Diseases 0.000 claims 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 208000000453 Skin Neoplasms Diseases 0.000 claims 1
- 206010041067 Small cell lung cancer Diseases 0.000 claims 1
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 1
- 230000021736 acetylation Effects 0.000 claims 1
- 238000006640 acetylation reaction Methods 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 238000004458 analytical method Methods 0.000 claims 1
- 230000006329 citrullination Effects 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 208000035250 cutaneous malignant susceptibility to 1 melanoma Diseases 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 230000004049 epigenetic modification Effects 0.000 claims 1
- 201000004101 esophageal cancer Diseases 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 238000013467 fragmentation Methods 0.000 claims 1
- 238000006062 fragmentation reaction Methods 0.000 claims 1
- 206010017758 gastric cancer Diseases 0.000 claims 1
- 206010073071 hepatocellular carcinoma Diseases 0.000 claims 1
- 231100000844 hepatocellular carcinoma Toxicity 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 201000007270 liver cancer Diseases 0.000 claims 1
- 208000014018 liver neoplasm Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 230000011987 methylation Effects 0.000 claims 1
- 238000007069 methylation reaction Methods 0.000 claims 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 230000026731 phosphorylation Effects 0.000 claims 1
- 238000006366 phosphorylation reaction Methods 0.000 claims 1
- 239000000523 sample Substances 0.000 claims 1
- 238000012163 sequencing technique Methods 0.000 claims 1
- 201000000849 skin cancer Diseases 0.000 claims 1
- 208000000587 small cell lung carcinoma Diseases 0.000 claims 1
- 201000011549 stomach cancer Diseases 0.000 claims 1
- 230000010741 sumoylation Effects 0.000 claims 1
- 230000005945 translocation Effects 0.000 claims 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 1
- 230000034512 ubiquitination Effects 0.000 claims 1
- 238000010798 ubiquitination Methods 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063024489P | 2020-05-13 | 2020-05-13 | |
| US63/024,489 | 2020-05-13 | ||
| US202063054617P | 2020-07-21 | 2020-07-21 | |
| US63/054,617 | 2020-07-21 | ||
| US202063065375P | 2020-08-13 | 2020-08-13 | |
| US63/065,375 | 2020-08-13 | ||
| US202063106741P | 2020-10-28 | 2020-10-28 | |
| US63/106,741 | 2020-10-28 | ||
| PCT/US2021/031815 WO2021231455A1 (en) | 2020-05-13 | 2021-05-11 | Cell-free dna size detection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023526032A JP2023526032A (ja) | 2023-06-20 |
| JP2023526032A5 JP2023526032A5 (https=) | 2024-05-21 |
| JPWO2021231455A5 true JPWO2021231455A5 (https=) | 2024-05-21 |
Family
ID=78524932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022568686A Pending JP2023526032A (ja) | 2020-05-13 | 2021-05-11 | セルフリーｄｎａサイズ検出 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230167508A1 (https=) |
| EP (1) | EP4150124A4 (https=) |
| JP (1) | JP2023526032A (https=) |
| CN (1) | CN116234930A (https=) |
| WO (1) | WO2021231455A1 (https=) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3191628B1 (en) * | 2014-09-12 | 2022-05-25 | The Board of Trustees of the Leland Stanford Junior University | Identification and use of circulating nucleic acids |
| CA3046007A1 (en) * | 2016-12-22 | 2018-06-28 | Guardant Health, Inc. | Methods and systems for analyzing nucleic acid molecules |
| US11305282B2 (en) * | 2017-03-29 | 2022-04-19 | Cornell University | Devices, processes, and systems for determination of nucleic acid sequence, expression, copy number, or methylation changes using combined nuclease, ligase, polymerase, and sequencing reactions |
| US11814686B2 (en) * | 2017-12-07 | 2023-11-14 | Institut National de la Santéde la Recherche Médicale | Method for screening and treating a subject for a cancer |
| US20210327535A1 (en) * | 2018-08-22 | 2021-10-21 | The Regents Of The University Of California | Sensitively detecting copy number variations (cnvs) from circulating cell-free nucleic acid |
| WO2020172566A1 (en) * | 2019-02-22 | 2020-08-27 | Accuragen Holdings Limited | Methods and compositions for early cancer detection |
-
2021
- 2021-05-11 CN CN202180061081.4A patent/CN116234930A/zh active Pending
- 2021-05-11 WO PCT/US2021/031815 patent/WO2021231455A1/en not_active Ceased
- 2021-05-11 EP EP21803049.2A patent/EP4150124A4/en active Pending
- 2021-05-11 JP JP2022568686A patent/JP2023526032A/ja active Pending
-
2022
- 2022-11-11 US US18/054,676 patent/US20230167508A1/en active Pending
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