JPWO2021228987A5 - - Google Patents

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Publication number
JPWO2021228987A5
JPWO2021228987A5 JP2022568518A JP2022568518A JPWO2021228987A5 JP WO2021228987 A5 JPWO2021228987 A5 JP WO2021228987A5 JP 2022568518 A JP2022568518 A JP 2022568518A JP 2022568518 A JP2022568518 A JP 2022568518A JP WO2021228987 A5 JPWO2021228987 A5 JP WO2021228987A5
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JP
Japan
Prior art keywords
seq
pharmaceutical product
ttr
antibody
designed
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JP2022568518A
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English (en)
Japanese (ja)
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JP7834032B2 (ja
JP2023525790A (ja
JP2023525790A5 (https=
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Priority claimed from PCT/EP2021/062706 external-priority patent/WO2021228987A1/en
Publication of JP2023525790A publication Critical patent/JP2023525790A/ja
Publication of JP2023525790A5 publication Critical patent/JP2023525790A5/ja
Publication of JPWO2021228987A5 publication Critical patent/JPWO2021228987A5/ja
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Publication of JP7834032B2 publication Critical patent/JP7834032B2/ja
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JP2022568518A 2020-05-12 2021-05-12 Ttrアミロイドーシスに対する併用療法 Active JP7834032B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20174177.4 2020-05-12
EP20174177 2020-05-12
PCT/EP2021/062706 WO2021228987A1 (en) 2020-05-12 2021-05-12 Combination therapy for ttr amyloidosis

Publications (4)

Publication Number Publication Date
JP2023525790A JP2023525790A (ja) 2023-06-19
JP2023525790A5 JP2023525790A5 (https=) 2024-05-23
JPWO2021228987A5 true JPWO2021228987A5 (https=) 2024-05-23
JP7834032B2 JP7834032B2 (ja) 2026-03-23

Family

ID=70682637

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022568518A Active JP7834032B2 (ja) 2020-05-12 2021-05-12 Ttrアミロイドーシスに対する併用療法

Country Status (13)

Country Link
US (1) US20230183329A1 (https=)
EP (1) EP4149972A1 (https=)
JP (1) JP7834032B2 (https=)
KR (1) KR20230009950A (https=)
CN (1) CN115551886A (https=)
AU (1) AU2021272369A1 (https=)
BR (1) BR112022023031A2 (https=)
CA (1) CA3172824A1 (https=)
CL (2) CL2022003141A1 (https=)
CO (1) CO2022017877A2 (https=)
IL (1) IL298135A (https=)
MX (1) MX2022014223A (https=)
WO (1) WO2021228987A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023099788A1 (en) * 2021-12-03 2023-06-08 Neurimmune Ag Novel potency assay for antibody-based drugs and useful means therefor
AU2023382527A1 (en) * 2022-11-15 2025-06-26 Alexion Pharmaceuticals, Inc. Methods for treating or preventing transthyretin-mediated amyloidosis
WO2024240562A1 (en) 2023-05-19 2024-11-28 Neurimmune Ag Novel immunotherapy for musculoskeletal disorders and conditions
WO2025104243A1 (en) 2023-11-15 2025-05-22 Neurimmune Ag Anti-transthyretin antibody, compositions comprising said antibody and methods for treating or preventing transthyretin-mediated amyloidosis
WO2025238147A1 (en) * 2024-05-15 2025-11-20 Neurimmune Ag Maintenance treatment of cardiac ttr amyloidosis using anti-transthyretin antibodies

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9283271B2 (en) 2010-12-17 2016-03-15 Neurimmune Holding Ag Human anti-SOD1 antibodies
US9169214B2 (en) 2012-12-21 2015-10-27 The Board Of Trustees Of The Leland Stanford Junior University Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions
US10344080B2 (en) * 2013-12-20 2019-07-09 Neurimmune Holding Ag Antibody-based therapy of transthyretin (TTR) amyloidosis and human-derived antibodies therefor
EP3101131B1 (en) 2014-01-29 2020-08-19 KM Biologics Co., Ltd. Anti-transthyretin humanized antibody
EP3981874A1 (en) 2014-01-29 2022-04-13 KM Biologics Co., Ltd. Anti-transthyretin human antibody
TWI786505B (zh) 2015-01-28 2022-12-11 愛爾蘭商普羅佘納生物科技有限公司 抗甲狀腺素運送蛋白抗體
WO2018007923A2 (en) 2016-07-02 2018-01-11 Prothena Biosciences Limited Anti-transthyretin antibodies
WO2018007922A2 (en) 2016-07-02 2018-01-11 Prothena Biosciences Limited Anti-transthyretin antibodies
JP7017013B2 (ja) 2016-07-02 2022-02-08 プロセナ バイオサイエンシーズ リミテッド 抗トランスサイレチン抗体
CU24731B1 (es) * 2017-10-06 2025-01-15 Prothena Biosciences Ltd Anticuerpos anti-transtiretina
CU20200042A7 (es) * 2017-11-29 2021-03-11 Prothena Biosciences Ltd Formulación liofilizada de un anticuerpo monoclonal contra la transtirretina
US20210400932A1 (en) 2018-11-09 2021-12-30 Neurimmune Ag Patient-derived amyloid xenograft non-human animal model

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