JPWO2021216936A5 - - Google Patents
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- JPWO2021216936A5 JPWO2021216936A5 JP2023509462A JP2023509462A JPWO2021216936A5 JP WO2021216936 A5 JPWO2021216936 A5 JP WO2021216936A5 JP 2023509462 A JP2023509462 A JP 2023509462A JP 2023509462 A JP2023509462 A JP 2023509462A JP WO2021216936 A5 JPWO2021216936 A5 JP WO2021216936A5
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| KR20240108406A (ko) | 2021-10-19 | 2024-07-09 | 아키라바이오, 인크. | 2'-데옥시시티딘 유사체를 포함하는 조성물 및 겸상 적혈구 질환, 지중해빈혈, 및 암의 치료를 위한 그의 용도 |
| WO2024191252A1 (ko) * | 2023-03-14 | 2024-09-19 | 주식회사 피노바이오 | 골수에 작용하는 5-아자-4'-티오-2'-데옥시사이티딘의 최고 혈중농도를 정교하게 제어가능한 경구용 제형 |
| CN117187391B (zh) * | 2023-09-15 | 2025-03-18 | 中国医学科学院北京协和医院 | 普卡霉素在垂体促肾上腺皮质激素腺瘤中的应用 |
| WO2025100762A1 (ko) * | 2023-11-08 | 2025-05-15 | 한국생명공학연구원 | 4'-티오-5-아자-2'-디옥시사이티딘을 포함하는 간질환의 개선, 예방 또는 치료용 조성물 |
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| US5591722A (en) | 1989-09-15 | 1997-01-07 | Southern Research Institute | 2'-deoxy-4'-thioribonucleosides and their antiviral activity |
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| EP3782612B1 (en) | 2008-05-15 | 2023-11-08 | Celgene Corporation | Oral formulations of cytidine analogs and methods of use thereof |
| WO2011109383A1 (en) | 2010-03-02 | 2011-09-09 | Southern Research Institute | Use of 2'-deoxy -4'-thiocytidine and its analogues as dna hypomethylating anticancer agents |
| US20110218170A1 (en) * | 2010-03-02 | 2011-09-08 | Southern Research Institute | Use of 2'-deoxy-4'-thiocytidine and its analogues as dna hypomethylating anticancer agents |
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| BR112016028641A2 (pt) * | 2014-07-14 | 2017-08-22 | Gilead Sciences Inc | ?método para tratar câncer? |
| TWI678373B (zh) | 2014-10-31 | 2019-12-01 | 日商富士軟片股份有限公司 | 硫代核苷衍生物或其鹽及醫藥組合物 |
| US10662214B2 (en) | 2015-04-03 | 2020-05-26 | Sichuan Keiun-Biotech Biopharmaceutical Co., Ltd. | Compound of 4′-thionucleoside, as well as preparation method therefor, pharmaceutical composition thereof and application thereof |
| US20160312261A1 (en) | 2015-04-24 | 2016-10-27 | Plasmia Biotech, S.L. | Enzymatic production of cytosinic nucleoside analogues |
| HK1252245A1 (zh) | 2015-05-27 | 2019-05-24 | Idenix Pharmaceuticals Llc | 用於治疗癌症的核苷酸 |
| EP3207932A1 (en) * | 2016-02-19 | 2017-08-23 | Universität Stuttgart | Dna methyltransferase inhibitors for rett syndrome therapy |
| US20190240210A1 (en) * | 2016-10-17 | 2019-08-08 | Daiichi Sankyo Company, Limited | Treatment Method by Combined Use of MDM2 Inhibitor and DNA Methyltransferase Inhibitor |
| JP7425734B2 (ja) | 2018-02-01 | 2024-01-31 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | ２’－デオキシヌクレオシドを製造するための立体選択的合成およびプロセス |
| CA3097003A1 (en) * | 2018-04-19 | 2019-10-24 | Southern Research Institute | 4'-thio-nucleotide and -nucleoside prodrugs for the treatment of cancer |
| JP7520822B2 (ja) | 2018-09-25 | 2024-07-23 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | ２’－ハロゲン化－４’－チオ－２’－デオキシ－５－アザシチジンアナログおよびその使用 |
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2024
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