JPWO2021202494A5 - - Google Patents

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Publication number
JPWO2021202494A5
JPWO2021202494A5 JP2022559694A JP2022559694A JPWO2021202494A5 JP WO2021202494 A5 JPWO2021202494 A5 JP WO2021202494A5 JP 2022559694 A JP2022559694 A JP 2022559694A JP 2022559694 A JP2022559694 A JP 2022559694A JP WO2021202494 A5 JPWO2021202494 A5 JP WO2021202494A5
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JP
Japan
Prior art keywords
composition
subject
raav
nucleic acid
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022559694A
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English (en)
Japanese (ja)
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JP2023529054A5 (https=
JP2023529054A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/024837 external-priority patent/WO2021202494A1/en
Publication of JP2023529054A publication Critical patent/JP2023529054A/ja
Publication of JP2023529054A5 publication Critical patent/JP2023529054A5/ja
Publication of JPWO2021202494A5 publication Critical patent/JPWO2021202494A5/ja
Pending legal-status Critical Current

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JP2022559694A 2020-03-31 2021-03-30 Aavキャプシドバリアントおよびその使用 Pending JP2023529054A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063003143P 2020-03-31 2020-03-31
US63/003,143 2020-03-31
PCT/US2021/024837 WO2021202494A1 (en) 2020-03-31 2021-03-30 Aav capsids variants and uses thereof

Publications (3)

Publication Number Publication Date
JP2023529054A JP2023529054A (ja) 2023-07-07
JP2023529054A5 JP2023529054A5 (https=) 2024-04-10
JPWO2021202494A5 true JPWO2021202494A5 (https=) 2024-04-10

Family

ID=75870702

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022559694A Pending JP2023529054A (ja) 2020-03-31 2021-03-30 Aavキャプシドバリアントおよびその使用

Country Status (14)

Country Link
US (1) US20230138766A1 (https=)
EP (1) EP4126911A1 (https=)
JP (1) JP2023529054A (https=)
KR (1) KR20230113689A (https=)
CN (1) CN115698039A (https=)
AR (1) AR122404A1 (https=)
AU (1) AU2021248577A1 (https=)
BR (1) BR112022019304A2 (https=)
CA (1) CA3177182A1 (https=)
CO (1) CO2022015313A2 (https=)
IL (1) IL296765A (https=)
MX (1) MX2022012279A (https=)
TW (1) TW202204377A (https=)
WO (1) WO2021202494A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010138263A2 (en) 2009-05-28 2010-12-02 University Of Massachusetts Novel aav 's and uses thereof
AU2019237514A1 (en) 2018-03-23 2020-10-08 University Of Massachusetts Gene therapeutics for treating bone disorders
MX2024004217A (es) 2021-10-08 2024-06-26 Dyno Therapeutics Inc Variantes de cápside y métodos de uso de estas.
WO2024020376A1 (en) * 2022-07-22 2024-01-25 University Of Massachusetts Aav-mediated delivery of osteoblast/osteoclast-regulating mirnas for osteoporosis therapy

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5549910A (en) 1989-03-31 1996-08-27 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
US5252334A (en) 1989-09-08 1993-10-12 Cygnus Therapeutic Systems Solid matrix system for transdermal drug delivery
JP3218637B2 (ja) 1990-07-26 2001-10-15 大正製薬株式会社 安定なリポソーム水懸濁液
JP2958076B2 (ja) 1990-08-27 1999-10-06 株式会社ビタミン研究所 遺伝子導入用多重膜リポソーム及び遺伝子捕捉多重膜リポソーム製剤並びにその製法
US5399363A (en) 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
US5478745A (en) 1992-12-04 1995-12-26 University Of Pittsburgh Recombinant viral vector system
US5543158A (en) 1993-07-23 1996-08-06 Massachusetts Institute Of Technology Biodegradable injectable nanoparticles
US5741516A (en) 1994-06-20 1998-04-21 Inex Pharmaceuticals Corporation Sphingosomes for enhanced drug delivery
US5795587A (en) 1995-01-23 1998-08-18 University Of Pittsburgh Stable lipid-comprising drug delivery complexes and methods for their production
US5697899A (en) 1995-02-07 1997-12-16 Gensia Feedback controlled drug delivery system
IE80468B1 (en) 1995-04-04 1998-07-29 Elan Corp Plc Controlled release biodegradable nanoparticles containing insulin
US5738868A (en) 1995-07-18 1998-04-14 Lipogenics Ltd. Liposome compositions and kits therefor
US6001650A (en) 1995-08-03 1999-12-14 Avigen, Inc. High-efficiency wild-type-free AAV helper functions
US5656016A (en) 1996-03-18 1997-08-12 Abbott Laboratories Sonophoretic drug delivery system
US5797898A (en) 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
US5783208A (en) 1996-07-19 1998-07-21 Theratech, Inc. Transdermal drug delivery matrix for coadministering estradiol and another steroid
US5779708A (en) 1996-08-15 1998-07-14 Cyberdent, Inc. Intraosseous drug delivery device and method
AU722624B2 (en) 1996-09-06 2000-08-10 Trustees Of The University Of Pennsylvania, The An inducible method for production of recombinant adeno-associated viruses utilizing T7 polymerase
US6177403B1 (en) 1996-10-21 2001-01-23 The Trustees Of The University Of Pennsylvania Compositions, methods, and apparatus for delivery of a macromolecular assembly to an extravascular tissue of an animal
US6156303A (en) 1997-06-11 2000-12-05 University Of Washington Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
NZ532635A (en) 2001-11-13 2007-05-31 Univ Pennsylvania A method of identifying unknown adeno-associated virus (AAV) sequences and a kit for the method
EP3134522B1 (en) 2014-04-25 2021-10-06 University of Massachusetts Recombinant aav vectors useful for reducing immunity against transgene products
IL248102B (en) * 2014-05-02 2022-07-01 Genzyme Corp aav vectors for gene therapy of the central nervous system and retina
EP3526333A4 (en) * 2016-10-13 2020-07-29 University of Massachusetts AAV CAPSIDE DESIGNS
US20200316221A1 (en) * 2016-10-13 2020-10-08 University Of Massachusetts Aav capsid designs

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