JPWO2021195066A5 - - Google Patents
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- Publication number
- JPWO2021195066A5 JPWO2021195066A5 JP2022557683A JP2022557683A JPWO2021195066A5 JP WO2021195066 A5 JPWO2021195066 A5 JP WO2021195066A5 JP 2022557683 A JP2022557683 A JP 2022557683A JP 2022557683 A JP2022557683 A JP 2022557683A JP WO2021195066 A5 JPWO2021195066 A5 JP WO2021195066A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- hydrogen
- epilepsy
- group
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062993359P | 2020-03-23 | 2020-03-23 | |
| US62/993,359 | 2020-03-23 | ||
| PCT/US2021/023653 WO2021195066A2 (en) | 2020-03-23 | 2021-03-23 | Kcnt1 inhibitors and methods of use |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2023518838A JP2023518838A (ja) | 2023-05-08 |
| JP2023518838A5 JP2023518838A5 (https=) | 2024-04-03 |
| JPWO2021195066A5 true JPWO2021195066A5 (https=) | 2024-04-03 |
| JP7838820B2 JP7838820B2 (ja) | 2026-04-01 |
Family
ID=77892612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022557683A Active JP7838820B2 (ja) | 2020-03-23 | 2021-03-23 | Ｋｃｎｔ１阻害剤及び使用方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230285377A1 (https=) |
| EP (1) | EP4125831A4 (https=) |
| JP (1) | JP7838820B2 (https=) |
| KR (1) | KR20230005168A (https=) |
| CN (2) | CN121868303A (https=) |
| AU (1) | AU2021241530A1 (https=) |
| BR (1) | BR112022019041A2 (https=) |
| CA (1) | CA3176609A1 (https=) |
| IL (1) | IL296649A (https=) |
| MX (2) | MX2022011813A (https=) |
| WO (1) | WO2021195066A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20250172745A (ko) * | 2019-05-03 | 2025-12-09 | 프락시스 프리시젼 메디신즈, 인크. | Kcnt1 억제제 및 사용 방법 |
| KR20220016086A (ko) * | 2019-05-03 | 2022-02-08 | 프락시스 프리시젼 메디신즈, 인크. | Kcnt1 억제제 및 사용 방법 |
| JP7699836B2 (ja) | 2020-02-28 | 2025-06-30 | プラクシス プレシジョン メディシンズ， インコーポレイテッド | Ｋｃｎｔ１阻害剤、および使用方法 |
| US11773088B2 (en) | 2020-11-02 | 2023-10-03 | Praxis Precision Medicines, Inc. | KCNT1 inhibitors and methods of use |
| WO2023211854A1 (en) * | 2022-04-25 | 2023-11-02 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors comprising a thiazole core and methods of use |
| WO2023211850A1 (en) * | 2022-04-25 | 2023-11-02 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors comprising an isoxazole or oxadiazole core and methods of use |
| IL316283A (en) * | 2022-04-25 | 2024-12-01 | Praxis Prec Medicines Inc | KCNT1 inhibitors comprising a pyrazole core and methods of use |
| EP4630399A1 (en) * | 2022-12-05 | 2025-10-15 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors comprising a phenyl, pyridine, or pyrimidine core and methods of use |
| TW202502311A (zh) * | 2023-03-29 | 2025-01-16 | 美商默沙東有限責任公司 | Il4i1抑制劑及其使用方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003221322A1 (en) * | 2002-03-07 | 2003-09-16 | Sds Biotech K.K. | Substituted isoxazole alkylamine derivative and agri- and horticultural fungicide |
| KR101195801B1 (ko) * | 2004-06-18 | 2012-11-05 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | Ｘａ 인자 억제제 |
| ATE478847T1 (de) * | 2006-09-15 | 2010-09-15 | Pfizer | Substituierte pyridylmethylbicyclocarboxyamidverbindungen |
| US9321727B2 (en) * | 2011-06-10 | 2016-04-26 | Hoffmann-La Roche Inc. | Pyridine derivatives as agonists of the CB2 receptor |
| TW201642855A (zh) * | 2015-03-10 | 2016-12-16 | 健臻公司 | 用於治療蛋白質病變之方法 |
| EP3275440B1 (en) * | 2015-03-25 | 2022-05-04 | National Center for Geriatrics and Gerontology | Novel oxadiazole derivative and pharmaceutical containing same |
-
2021
- 2021-03-23 KR KR1020227036699A patent/KR20230005168A/ko active Pending
- 2021-03-23 JP JP2022557683A patent/JP7838820B2/ja active Active
- 2021-03-23 CN CN202610125645.0A patent/CN121868303A/zh active Pending
- 2021-03-23 IL IL296649A patent/IL296649A/en unknown
- 2021-03-23 WO PCT/US2021/023653 patent/WO2021195066A2/en not_active Ceased
- 2021-03-23 BR BR112022019041A patent/BR112022019041A2/pt unknown
- 2021-03-23 EP EP21774687.4A patent/EP4125831A4/en active Pending
- 2021-03-23 US US17/906,893 patent/US20230285377A1/en active Pending
- 2021-03-23 AU AU2021241530A patent/AU2021241530A1/en active Pending
- 2021-03-23 CN CN202180035479.0A patent/CN115715189B/zh active Active
- 2021-03-23 MX MX2022011813A patent/MX2022011813A/es unknown
- 2021-03-23 CA CA3176609A patent/CA3176609A1/en active Pending
-
2022
- 2022-09-22 MX MX2026000122A patent/MX2026000122A/es unknown
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