JPWO2021138434A5 - - Google Patents

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JPWO2021138434A5
JPWO2021138434A5 JP2022540328A JP2022540328A JPWO2021138434A5 JP WO2021138434 A5 JPWO2021138434 A5 JP WO2021138434A5 JP 2022540328 A JP2022540328 A JP 2022540328A JP 2022540328 A JP2022540328 A JP 2022540328A JP WO2021138434 A5 JPWO2021138434 A5 JP WO2021138434A5
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JP2022540328A
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Japanese (ja)
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JP2023509422A5 (https=
JP2023509422A (ja
JP7756643B2 (ja
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Priority claimed from PCT/US2020/067483 external-priority patent/WO2021138434A1/en
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JP2022540328A 2019-12-31 2020-12-30 Ｓｔｉｎｇ活性に関連する状態を治療するための化合物および組成物 Active JP7756643B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962955839P 2019-12-31 2019-12-31
US62/955,839 2019-12-31
US202063090538P 2020-10-12 2020-10-12
US63/090,538 2020-10-12
PCT/US2020/067483 WO2021138434A1 (en) 2019-12-31 2020-12-30 Compounds and compositions for treating conditions associated with sting activity

Publications (4)

Publication Number Publication Date
JP2023509422A JP2023509422A (ja) 2023-03-08
JP2023509422A5 JP2023509422A5 (https=) 2024-01-11
JPWO2021138434A5 true JPWO2021138434A5 (https=) 2024-01-11
JP7756643B2 JP7756643B2 (ja) 2025-10-20

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ID=74206237

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Application Number Title Priority Date Filing Date
JP2022540328A Active JP7756643B2 (ja) 2019-12-31 2020-12-30 Ｓｔｉｎｇ活性に関連する状態を治療するための化合物および組成物

Country Status (8)

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US (1) US20230127839A1 (https=)
EP (1) EP4085051A1 (https=)
JP (1) JP7756643B2 (https=)
CN (2) CN120965654A (https=)
PY (1) PY2089159A (https=)
TW (1) TW202136239A (https=)
UY (1) UY39006A (https=)
WO (1) WO2021138434A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112823036B (zh) 2018-07-03 2024-11-08 艾福姆德尤股份有限公司 用于治疗与sting活性有关的疾病的化合物和组合物
EP4267129A1 (en) 2020-12-22 2023-11-01 IFM Due, Inc. Methods of treating cancer
WO2022140397A1 (en) 2020-12-22 2022-06-30 Ifm Due, Inc. Methods of treating cancer
US20240060982A1 (en) 2020-12-22 2024-02-22 Ifm Due, Inc. Methods of treating cancer
EP4267128A1 (en) 2020-12-22 2023-11-01 IFM Due, Inc. Methods of treating cancer
TW202235073A (zh) 2021-01-08 2022-09-16 美商Ｉｆｍ Ｄｕｅ有限公司 用於治療與sting活性相關的病狀之化合物及組合物
JP2024502470A (ja) * 2021-01-08 2024-01-19 アイエフエム デュー インコーポレイテッド Ｓｔｉｎｇ活性に関連する状態を治療するための化合物および組成物
CN116981668A (zh) * 2021-04-09 2023-10-31 百济神州(北京)生物科技有限公司 制备bcl-2抑制剂的中间体的方法
UY39892A (es) 2021-08-10 2023-03-31 Novartis Pharma Ag Compuestos y composiciones para tratar afecciones asociadas con la actividad de STING
WO2024064358A1 (en) 2022-09-23 2024-03-28 Ifm Due, Inc. Compounds and compositions for treating conditions associated with sting activity
CN117756698A (zh) * 2022-12-16 2024-03-26 中国药科大学 脲类化合物及其作为sting抑制剂的医药用途
CN116023321B (zh) * 2022-12-30 2024-11-29 中国药科大学 Sting抑制剂前药及其医药用途
CN120794982A (zh) * 2024-05-14 2025-10-17 中国药科大学 吡唑类sting抑制剂及其医药用途
CN120794957A (zh) * 2024-05-14 2025-10-17 中国药科大学 苯并含氮杂环类sting抑制剂及其医药用途
WO2026023667A1 (ja) * 2024-07-25 2026-01-29 カルナバイオサイエンス株式会社 フェニルピペラジン誘導体

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JPS5783558A (en) * 1980-11-13 1982-05-25 Asahi Chem Ind Co Ltd Novel organic compound and its preparation
JPS5783557A (en) * 1980-11-14 1982-05-25 Asahi Chem Ind Co Ltd Novel azomethine compound and its preparation
US20120046290A1 (en) * 1997-12-22 2012-02-23 Jacques Dumas Inhibition of p38 kinase activity using substituted heterocyclic ureas
WO2003028720A1 (en) * 2001-09-26 2003-04-10 Pharmacia Italia S.P.A. Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them
US7927613B2 (en) 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
DE102005038947A1 (de) * 2005-05-18 2006-11-30 Grünenthal GmbH Substituierte Benzo[d]isoxazol-3-yl-amin-Verbindungen und deren Verwendung in Arzneimitteln
US8188113B2 (en) * 2006-09-14 2012-05-29 Deciphera Pharmaceuticals, Inc. Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
WO2012062462A1 (en) * 2010-11-10 2012-05-18 Grünenthal GmbH Substituted heteroaromatic carboxamide and urea derivatives as vanilloid receptor ligands
WO2012075380A1 (en) 2010-12-03 2012-06-07 The Trustees Of The University Of Pennsylvania Tip60 inhibitors
CN102516153B (zh) * 2011-12-14 2014-03-12 南京工业大学 5-氟吲哚-2-酮-3-脲类化合物及其制备方法和应用
CA2914815A1 (en) * 2013-06-11 2014-12-18 Kala Pharmaceuticals, Inc. Urea derivatives and uses thereof
CN109394752A (zh) 2013-10-21 2019-03-01 德雷克塞尔大学 治疗慢性乙型肝炎病毒感染的sting激动剂的用途
CN107417478B (zh) * 2017-06-05 2020-05-05 南京师范大学 一种催化氧化羰基化合成不对称二取代脲的方法
EP3556362A1 (en) * 2018-04-16 2019-10-23 Ecole Polytechnique Federale De Lausanne (Epfl) Sting inhibitors
WO2020191227A1 (en) * 2019-03-20 2020-09-24 Cornell University Methods for controlling prostaglandin-mediated biological processes
EP4267128A1 (en) * 2020-12-22 2023-11-01 IFM Due, Inc. Methods of treating cancer
EP4267129A1 (en) * 2020-12-22 2023-11-01 IFM Due, Inc. Methods of treating cancer
WO2022140397A1 (en) * 2020-12-22 2022-06-30 Ifm Due, Inc. Methods of treating cancer
US20240060982A1 (en) * 2020-12-22 2024-02-22 Ifm Due, Inc. Methods of treating cancer

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