JPWO2021136303A5 - - Google Patents
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- Publication number
- JPWO2021136303A5 JPWO2021136303A5 JP2022540870A JP2022540870A JPWO2021136303A5 JP WO2021136303 A5 JPWO2021136303 A5 JP WO2021136303A5 JP 2022540870 A JP2022540870 A JP 2022540870A JP 2022540870 A JP2022540870 A JP 2022540870A JP WO2021136303 A5 JPWO2021136303 A5 JP WO2021136303A5
- Authority
- JP
- Japan
- Prior art keywords
- human insulin
- γglu
- desb30 human
- docosandioyl
- eicosandioyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911397405.2 | 2019-12-30 | ||
| CN201911397405 | 2019-12-30 | ||
| CN202011053306.5 | 2020-09-29 | ||
| CN202011053306 | 2020-09-29 | ||
| PCT/CN2020/141057 WO2021136303A1 (zh) | 2019-12-30 | 2020-12-29 | 长效glp-1化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023510218A JP2023510218A (ja) | 2023-03-13 |
| JPWO2021136303A5 true JPWO2021136303A5 (https=) | 2025-10-27 |
| JP2023510218A5 JP2023510218A5 (https=) | 2025-10-27 |
Family
ID=76687327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022540870A Pending JP2023510218A (ja) | 2019-12-30 | 2020-12-29 | 長時間作用型ｇｌｐ－１化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20240239859A1 (https=) |
| EP (1) | EP4086277A4 (https=) |
| JP (1) | JP2023510218A (https=) |
| KR (1) | KR20220119731A (https=) |
| CN (5) | CN119529057A (https=) |
| AU (1) | AU2020418207A1 (https=) |
| BR (1) | BR112022013042A2 (https=) |
| CA (1) | CA3166496A1 (https=) |
| MX (1) | MX2022008139A (https=) |
| WO (1) | WO2021136303A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020417892A1 (en) * | 2019-12-30 | 2022-08-25 | Gan & Lee Pharmaceuticals Co., Ltd. | Insulin derivative |
| CN119529057A (zh) * | 2019-12-30 | 2025-02-28 | 甘李药业股份有限公司 | 长效glp-1化合物 |
| WO2022159395A1 (en) | 2021-01-20 | 2022-07-28 | Viking Therapeutics, Inc. | Compositions and methods for the treatment of metabolic and liver disorders |
| EP4360645A4 (en) * | 2021-06-25 | 2025-09-10 | Gan & Lee Pharmaceuticals Co Ltd | PHARMACEUTICAL COMPOSITION CONTAINING A GLP-1 COMPOUND |
| MX2024003236A (es) | 2021-09-15 | 2024-06-19 | Viking Therapeutics Inc | Composiciones y metodos para el tratamiento de trastornos metabolicos y hepaticos. |
| CA3237796A1 (en) * | 2021-11-12 | 2023-05-19 | Zhenbin Li | Pharmaceutical composition of glp-1 receptor and gip receptor dual agonist, and use thereof |
| CN118574842A (zh) * | 2022-01-28 | 2024-08-30 | 甘李药业股份有限公司 | 酰化胰岛素 |
| CN120731085A (zh) * | 2023-03-02 | 2025-09-30 | 甘李药业股份有限公司 | 一种glp-1化合物的医药用途 |
| EP4722236A1 (en) * | 2023-05-24 | 2026-04-08 | The United Bio-Technology (Hengqin) Co., Ltd. | Insulin derivative and use thereof |
| WO2025005743A1 (ko) * | 2023-06-30 | 2025-01-02 | 주식회사 휴온스랩 | Glp 유사체를 유효성분으로 포함하는 비만 예방 또는 치료용 약학적 조성물 |
| WO2025098415A1 (zh) * | 2023-11-06 | 2025-05-15 | 甘李药业股份有限公司 | 用于降糖的glp-1化合物 |
| WO2025098416A1 (zh) * | 2023-11-06 | 2025-05-15 | 甘李药业股份有限公司 | 用于减肥的glp-1化合物 |
| WO2025098457A1 (zh) * | 2023-11-07 | 2025-05-15 | 甘李药业股份有限公司 | 用于降糖的酰化胰岛素 |
| WO2025098502A1 (zh) * | 2023-11-08 | 2025-05-15 | 甘李药业股份有限公司 | 包含胰岛素衍生物的药物组合物的治疗用途 |
| TW202529797A (zh) * | 2023-12-12 | 2025-08-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | Ｇｌｐ－１類似物治療代謝疾病的方法及醫藥用途 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ199391A (en) | 1981-01-02 | 1985-12-13 | Genentech Inc | Chimeric polypeptides comprising a proinsulin sequence,and preparation by recombinant dna technique;production of human insulin |
| DK58285D0 (da) | 1984-05-30 | 1985-02-08 | Novo Industri As | Peptider samt fremstilling og anvendelse deraf |
| PH25772A (en) | 1985-08-30 | 1991-10-18 | Novo Industri As | Insulin analogues, process for their preparation |
| DK336188D0 (da) | 1988-06-20 | 1988-06-20 | Nordisk Gentofte | Propeptider |
| KR910700262A (ko) | 1988-12-23 | 1991-03-14 | 안네 제케르 | 사람 인슐린 유사체 |
| PT93057B (pt) | 1989-02-09 | 1995-12-29 | Lilly Co Eli | Processo para a preparacao de analogos da insulina |
| CZ287945B6 (cs) | 1993-09-17 | 2001-03-14 | Novo Nordisk A/S | Inzulinový derivát a farmaceutický prostředek s jeho obsahem pro léčení diabetu |
| AU1272295A (en) | 1993-12-17 | 1995-07-03 | Novo Nordisk A/S | Proinsulin-like compounds |
| US6500645B1 (en) | 1994-06-17 | 2002-12-31 | Novo Nordisk A/S | N-terminally extended proteins expressed in yeast |
| KR0150565B1 (ko) | 1995-02-15 | 1998-08-17 | 김정재 | 유전자 조환에 의한 사람 인슐린 전구체의 제조 및 이를 이용한 인슐린의 제조방법 |
| EP0741188A3 (en) | 1995-05-05 | 1999-07-14 | Eli Lilly And Company | Single chain insulin with high bioactivity |
| IL128332A0 (en) | 1996-08-30 | 2000-01-31 | Novo Nordisk As | GLP-1 derivatives |
| JP2003522099A (ja) | 1998-02-27 | 2003-07-22 | ノボ ノルディスク アクティーゼルスカブ | 遅延作用プロファイルを有するｇｌｐ−１のｇｌｐ−１誘導体及びエキセンジン |
| MXPA06015049A (es) * | 2004-07-08 | 2007-02-08 | Novo Nordisk As | Marcadores prolongadores de polipeptidos que comprenden una porcion tetrazol. |
| TWI372629B (en) * | 2005-03-18 | 2012-09-21 | Novo Nordisk As | Acylated glp-1 compounds |
| KR20100053561A (ko) * | 2007-08-15 | 2010-05-20 | 노보 노르디스크 에이/에스 | 아실 및 알킬렌 글리콜 부분을 갖는 인슐린 유사체 |
| EP2178910B1 (en) * | 2007-08-15 | 2014-10-08 | Novo Nordisk A/S | Insulins with an acyl moiety comprising repeating units of alkylene glycol containing amino acids |
| WO2009030774A1 (en) * | 2007-09-05 | 2009-03-12 | Novo Nordisk A/S | Truncated glp-1 derivatives and their therapeutical use |
| US20100261637A1 (en) * | 2007-09-05 | 2010-10-14 | Novo Nordisk A/S | Peptides derivatized with a-b-c-d- and their therapeutical use |
| CN102037008B (zh) * | 2008-03-18 | 2016-08-31 | 诺沃-诺迪斯克有限公司 | 蛋白酶稳定化的、酰化胰岛素类似物 |
| US8788849B2 (en) * | 2011-02-28 | 2014-07-22 | Sandisk Technologies Inc. | Method and apparatus for protecting cached streams |
| HRP20251088T1 (hr) * | 2012-07-01 | 2025-11-07 | Novo Nordisk A/S | Upotreba dugodjelujućih peptida glp‑1 |
| MX2018002223A (es) * | 2015-08-25 | 2018-03-23 | Novo Nordisk As | Derivados de insulina novedosos y usos medicos de los mismos. |
| EP3463429A4 (en) * | 2016-05-24 | 2020-07-22 | Merck Sharp & Dohme Corp. | PARTIAL INSULIN RECEPTOR AGONISTS AND GLP-1 ANALOGUES |
| TWI700091B (zh) * | 2016-12-16 | 2020-08-01 | 丹麥商諾佛 儂迪克股份有限公司 | 含胰島素醫藥組成物 |
| CN109248323B (zh) * | 2017-07-14 | 2023-09-08 | 杭州先为达生物科技有限公司 | 酰化的glp-1衍生物 |
| WO2019200594A1 (zh) * | 2018-04-19 | 2019-10-24 | 杭州先为达生物科技有限公司 | 酰化的glp-1衍生物 |
| AU2020417892A1 (en) * | 2019-12-30 | 2022-08-25 | Gan & Lee Pharmaceuticals Co., Ltd. | Insulin derivative |
| CN119529057A (zh) * | 2019-12-30 | 2025-02-28 | 甘李药业股份有限公司 | 长效glp-1化合物 |
-
2020
- 2020-12-29 CN CN202411172451.3A patent/CN119529057A/zh active Pending
- 2020-12-29 US US17/758,113 patent/US20240239859A1/en active Pending
- 2020-12-29 CA CA3166496A patent/CA3166496A1/en active Pending
- 2020-12-29 CN CN202411172407.2A patent/CN119060161A/zh active Pending
- 2020-12-29 KR KR1020227026310A patent/KR20220119731A/ko active Pending
- 2020-12-29 BR BR112022013042A patent/BR112022013042A2/pt unknown
- 2020-12-29 EP EP20909624.7A patent/EP4086277A4/en active Pending
- 2020-12-29 CN CN202411172489.0A patent/CN119060162A/zh active Pending
- 2020-12-29 WO PCT/CN2020/141057 patent/WO2021136303A1/zh not_active Ceased
- 2020-12-29 CN CN202080091240.0A patent/CN114901680B/zh active Active
- 2020-12-29 MX MX2022008139A patent/MX2022008139A/es unknown
- 2020-12-29 JP JP2022540870A patent/JP2023510218A/ja active Pending
- 2020-12-29 CN CN202411172559.2A patent/CN119060163A/zh active Pending
- 2020-12-29 AU AU2020418207A patent/AU2020418207A1/en active Pending
-
2024
- 2024-09-12 US US18/883,592 patent/US20250011385A1/en not_active Abandoned
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