JPWO2021113558A5 - - Google Patents
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- Publication number
- JPWO2021113558A5 JPWO2021113558A5 JP2022532869A JP2022532869A JPWO2021113558A5 JP WO2021113558 A5 JPWO2021113558 A5 JP WO2021113558A5 JP 2022532869 A JP2022532869 A JP 2022532869A JP 2022532869 A JP2022532869 A JP 2022532869A JP WO2021113558 A5 JPWO2021113558 A5 JP WO2021113558A5
- Authority
- JP
- Japan
- Prior art keywords
- epitope
- cells
- antigen binding
- bin
- binding sites
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003795 chemical substances by application Substances 0.000 claims 41
- 210000001744 T-lymphocyte Anatomy 0.000 claims 30
- 239000000427 antigen Substances 0.000 claims 28
- 108091007433 antigens Proteins 0.000 claims 28
- 102000036639 antigens Human genes 0.000 claims 28
- 238000000034 method Methods 0.000 claims 27
- 210000004027 cell Anatomy 0.000 claims 16
- 230000009258 tissue cross reactivity Effects 0.000 claims 13
- 239000003814 drug Substances 0.000 claims 10
- 229940079593 drug Drugs 0.000 claims 10
- 102000004127 Cytokines Human genes 0.000 claims 9
- 108090000695 Cytokines Proteins 0.000 claims 9
- 230000004913 activation Effects 0.000 claims 6
- 238000000338 in vitro Methods 0.000 claims 6
- 108010002350 Interleukin-2 Proteins 0.000 claims 4
- 102000000588 Interleukin-2 Human genes 0.000 claims 4
- 230000003213 activating effect Effects 0.000 claims 4
- 108090000172 Interleukin-15 Proteins 0.000 claims 3
- 230000035772 mutation Effects 0.000 claims 3
- 229920001184 polypeptide Polymers 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 108090000978 Interleukin-4 Proteins 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 241000255925 Diptera Species 0.000 claims 1
- -1 IL 23 Proteins 0.000 claims 1
- 108010002586 Interleukin-7 Proteins 0.000 claims 1
- 108010002335 Interleukin-9 Proteins 0.000 claims 1
- 108091008874 T cell receptors Proteins 0.000 claims 1
- 108700019146 Transgenes Proteins 0.000 claims 1
- 230000000735 allogeneic effect Effects 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000000644 propagated effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962943166P | 2019-12-03 | 2019-12-03 | |
| US62/943,166 | 2019-12-03 | ||
| PCT/US2020/063177 WO2021113558A2 (en) | 2019-12-03 | 2020-12-03 | METHODS FOR EXPANDING γδ T-CELL POPULATIONS WITH MULTIVALENT AGENTS AND COMPOSITIONS THEREOF |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023504185A JP2023504185A (ja) | 2023-02-01 |
| JPWO2021113558A5 true JPWO2021113558A5 (https=) | 2024-01-31 |
| JP2023504185A5 JP2023504185A5 (https=) | 2024-01-31 |
Family
ID=76222296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022532869A Pending JP2023504185A (ja) | 2019-12-03 | 2020-12-03 | γδＴ細胞集団を多価薬剤で増殖させるための方法及びその組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230009275A1 (https=) |
| EP (1) | EP4072567A4 (https=) |
| JP (1) | JP2023504185A (https=) |
| KR (1) | KR20220123652A (https=) |
| CN (1) | CN115397976A (https=) |
| AU (1) | AU2020398623A1 (https=) |
| CA (1) | CA3160609A1 (https=) |
| IL (1) | IL293459A (https=) |
| MX (1) | MX2022006547A (https=) |
| WO (1) | WO2021113558A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240130130A (ko) * | 2022-01-05 | 2024-08-28 | 인히브릭스 바이오사이언스, 인크. | 감마 델타 t 세포 결합 폴리펩티드 및 그의 용도 |
| EP4508193A4 (en) * | 2022-04-11 | 2026-04-29 | In8Bio Inc | Ipsc-based gamma-delta t-cells, compositions and methods of use thereof |
| CN121793981A (zh) * | 2023-10-18 | 2026-04-03 | 南京传奇生物科技有限公司 | Pan T细胞及其制造方法 |
| WO2026013159A1 (en) * | 2024-07-10 | 2026-01-15 | Cytospire Therapeutics Limited | Antibodies binding to constant domains of gamma delta t-cell receptors |
| WO2026013158A1 (en) * | 2024-07-10 | 2026-01-15 | Cytospire Therapeutics Limited | Antibodies binding to constant domains of gamma delta t-cell receptors |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001022816A1 (en) * | 1999-09-30 | 2001-04-05 | National Jewish Medical And Research Center | MODULATION OF ηδ T CELLS TO REGULATE AIRWAY HYPERRESPONSIVENESS |
| BR112017004270B1 (pt) * | 2014-09-04 | 2023-03-07 | Stemcell Technologies Inc | Método de ativação de células t ou células nk |
| WO2016081518A2 (en) * | 2014-11-17 | 2016-05-26 | Adicet Bio, Inc. | Engineered gamma delta t-cells |
| EP3454870A4 (en) * | 2016-05-12 | 2020-03-04 | Adicet Bio Inc. | METHOD FOR SELECTIVE EXPANSION OF GAMMA DELTA T CELL POPULATIONS AND COMPOSITIONS THEREOF |
| GB201707048D0 (en) * | 2017-05-03 | 2017-06-14 | King S College London | Expansion of gamma delta cells, compositions, and methods of use thereof |
| WO2019099744A1 (en) * | 2017-11-15 | 2019-05-23 | Adicet Bio, Inc. | METHODS FOR SELECTIVE EXPANSION OF δ3 γδ T-CELL POPULATIONS AND COMPOSITIONS THEREOF |
| DE102017127984B4 (de) * | 2017-11-27 | 2019-12-05 | Immatics US, Inc. | Verfahren für die Vermehrung und Aktivierung von γδ-T-Zellen |
| WO2020117862A1 (en) * | 2018-12-03 | 2020-06-11 | Adicet Bio, Inc. | Methods for selective in vivo expansion of gamma delta t-cell populations and compositions thereof |
-
2020
- 2020-12-03 JP JP2022532869A patent/JP2023504185A/ja active Pending
- 2020-12-03 EP EP20896270.4A patent/EP4072567A4/en active Pending
- 2020-12-03 CA CA3160609A patent/CA3160609A1/en active Pending
- 2020-12-03 US US17/782,129 patent/US20230009275A1/en active Pending
- 2020-12-03 MX MX2022006547A patent/MX2022006547A/es unknown
- 2020-12-03 WO PCT/US2020/063177 patent/WO2021113558A2/en not_active Ceased
- 2020-12-03 KR KR1020227022477A patent/KR20220123652A/ko active Pending
- 2020-12-03 IL IL293459A patent/IL293459A/en unknown
- 2020-12-03 AU AU2020398623A patent/AU2020398623A1/en active Pending
- 2020-12-03 CN CN202080094563.5A patent/CN115397976A/zh active Pending
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