JPWO2021107133A1 - - Google Patents
Info
- Publication number
- JPWO2021107133A1 JPWO2021107133A1 JP2021561569A JP2021561569A JPWO2021107133A1 JP WO2021107133 A1 JPWO2021107133 A1 JP WO2021107133A1 JP 2021561569 A JP2021561569 A JP 2021561569A JP 2021561569 A JP2021561569 A JP 2021561569A JP WO2021107133 A1 JPWO2021107133 A1 JP WO2021107133A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
- C12Y301/01001—Carboxylesterase (3.1.1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/07—Bacillus
- C12R2001/125—Bacillus subtilis ; Hay bacillus; Grass bacillus
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019217460 | 2019-11-29 | ||
| JP2019217460 | 2019-11-29 | ||
| PCT/JP2020/044347 WO2021107133A1 (ja) | 2019-11-29 | 2020-11-27 | メイタンシノールの酵素的生産方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2021107133A1 true JPWO2021107133A1 (https=) | 2021-06-03 |
| JP7772363B2 JP7772363B2 (ja) | 2025-11-18 |
Family
ID=76129659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021561569A Active JP7772363B2 (ja) | 2019-11-29 | 2020-11-27 | メイタンシノールの酵素的生産方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US12473579B2 (https=) |
| EP (1) | EP4067497A4 (https=) |
| JP (1) | JP7772363B2 (https=) |
| WO (1) | WO2021107133A1 (https=) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002016368A1 (en) * | 2000-08-18 | 2002-02-28 | Immunogen, Inc. | Process for the preparation and purification of thiol-containing maytansinoids |
| WO2011102388A1 (ja) * | 2010-02-16 | 2011-08-25 | 株式会社エーピーアイ コーポレーション | １－アミノ－１－アルコキシカルボニル－２－ビニルシクロプロパンの製造方法 |
| WO2012029819A1 (ja) * | 2010-08-31 | 2012-03-08 | 株式会社エーピーアイ コーポレーション | 新規加水分解酵素タンパク質 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5529972A (en) | 1978-08-24 | 1980-03-03 | Takeda Chem Ind Ltd | Preparation of maytansinol |
| JPS61123719A (ja) | 1984-11-19 | 1986-06-11 | Mazda Motor Corp | タ−ボ過給機の潤滑装置 |
| US20020156274A1 (en) | 2001-03-16 | 2002-10-24 | Terfloth Gerald J. | Process for preparing maytansinol |
| EP1945647B9 (en) | 2005-11-08 | 2012-11-14 | Immunogen, Inc. | Processes for preparation of maytansinol |
| ES2327480B1 (es) | 2007-06-15 | 2010-08-10 | Bioiberica, S.A. | "disacaridos para el tratamiento de tendones, ligamentos y huesos". |
| LT3486248T (lt) | 2012-09-26 | 2021-08-25 | Immunogen, Inc. | Patobulinti maitansinolio acilinimo būdai |
-
2020
- 2020-11-27 JP JP2021561569A patent/JP7772363B2/ja active Active
- 2020-11-27 WO PCT/JP2020/044347 patent/WO2021107133A1/ja not_active Ceased
- 2020-11-27 US US17/779,967 patent/US12473579B2/en active Active
- 2020-11-27 EP EP20893404.2A patent/EP4067497A4/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002016368A1 (en) * | 2000-08-18 | 2002-02-28 | Immunogen, Inc. | Process for the preparation and purification of thiol-containing maytansinoids |
| WO2011102388A1 (ja) * | 2010-02-16 | 2011-08-25 | 株式会社エーピーアイ コーポレーション | １－アミノ－１－アルコキシカルボニル－２－ビニルシクロプロパンの製造方法 |
| WO2012029819A1 (ja) * | 2010-08-31 | 2012-03-08 | 株式会社エーピーアイ コーポレーション | 新規加水分解酵素タンパク質 |
Non-Patent Citations (1)
| Title |
|---|
| ZOCK J., ET AL.: "The Bacillus subtilis pnbA gene encoding p-nitrobenzyl esterase: cloning, sequence and high-level ex", GENE, vol. 151, JPN6021000706, 1994, pages 37 - 43, ISSN: 0005696572 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4067497A1 (en) | 2022-10-05 |
| WO2021107133A1 (ja) | 2021-06-03 |
| US20230030526A1 (en) | 2023-02-02 |
| EP4067497A4 (en) | 2024-03-13 |
| JP7772363B2 (ja) | 2025-11-18 |
| US12473579B2 (en) | 2025-11-18 |
| WO2021107133A8 (ja) | 2021-09-30 |
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