JPWO2021081133A5 - - Google Patents

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Publication number
JPWO2021081133A5
JPWO2021081133A5 JP2022523383A JP2022523383A JPWO2021081133A5 JP WO2021081133 A5 JPWO2021081133 A5 JP WO2021081133A5 JP 2022523383 A JP2022523383 A JP 2022523383A JP 2022523383 A JP2022523383 A JP 2022523383A JP WO2021081133 A5 JPWO2021081133 A5 JP WO2021081133A5
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JP
Japan
Prior art keywords
binding domain
fragment
cell
receptor
polynucleotide construct
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022523383A
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English (en)
Japanese (ja)
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JP2022553292A5 (https=
JP2022553292A (ja
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Application filed filed Critical
Priority claimed from PCT/US2020/056723 external-priority patent/WO2021081133A1/en
Publication of JP2022553292A publication Critical patent/JP2022553292A/ja
Publication of JP2022553292A5 publication Critical patent/JP2022553292A5/ja
Publication of JPWO2021081133A5 publication Critical patent/JPWO2021081133A5/ja
Pending legal-status Critical Current

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JP2022523383A 2019-10-21 2020-10-21 操作されたナチュラルキラー細胞、ならびに免疫療法およびオートファジー阻害技法においてそれを使用するための方法 Pending JP2022553292A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962923644P 2019-10-21 2019-10-21
US62/923,644 2019-10-21
PCT/US2020/056723 WO2021081133A1 (en) 2019-10-21 2020-10-21 Engineered natural killer cells and methods for using the same in immunotherapy and autophagy inhibition techniques

Publications (3)

Publication Number Publication Date
JP2022553292A JP2022553292A (ja) 2022-12-22
JP2022553292A5 JP2022553292A5 (https=) 2024-01-04
JPWO2021081133A5 true JPWO2021081133A5 (https=) 2024-01-04

Family

ID=75620220

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022523383A Pending JP2022553292A (ja) 2019-10-21 2020-10-21 操作されたナチュラルキラー細胞、ならびに免疫療法およびオートファジー阻害技法においてそれを使用するための方法

Country Status (6)

Country Link
US (1) US20220362299A1 (https=)
EP (1) EP4048292A4 (https=)
JP (1) JP2022553292A (https=)
AU (1) AU2020371628A1 (https=)
CA (1) CA3155246A1 (https=)
WO (1) WO2021081133A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021392032A1 (en) 2020-12-03 2023-06-22 Century Therapeutics, Inc. Genetically engineered cells and uses thereof
US11661459B2 (en) 2020-12-03 2023-05-30 Century Therapeutics, Inc. Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
AR124414A1 (es) 2020-12-18 2023-03-22 Century Therapeutics Inc Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable
CN113621073A (zh) * 2021-07-14 2021-11-09 上海易慕峰生物科技有限公司 一种新型嵌合受体组合物、重组载体、细胞及其应用
CN120459135B (zh) * 2025-07-16 2025-10-10 深圳市中佳生物医疗科技有限公司 Cd73+nk细胞在制备预防或治疗帕金森的药物中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1914242A1 (en) * 2006-10-19 2008-04-23 Sanofi-Aventis Novel anti-CD38 antibodies for the treatment of cancer
EP2948544A4 (en) * 2013-01-28 2016-08-03 St Jude Childrens Res Hospital CHIMERIC RECEPTOR WITH NKG2D SPECIFICITY FOR CELL THERAPY AGAINST CANCER AND INFECTION DISEASES
GB201403972D0 (en) * 2014-03-06 2014-04-23 Ucl Business Plc Chimeric antigen receptor
EP3218407A1 (en) * 2014-11-11 2017-09-20 Medimmune Limited Therapeutic combinations comprising anti-cd73 antibodies and a2a receptor inhibitor and uses thereof
MY189836A (en) * 2014-11-21 2022-03-11 Bristol Myers Squibb Co Antibodies against cd73 and uses thereof
CN105384825B (zh) * 2015-08-11 2018-06-01 南京传奇生物科技有限公司 一种基于单域抗体的双特异性嵌合抗原受体及其应用
WO2017172981A2 (en) 2016-03-29 2017-10-05 University Of Southern California Chimeric antigen receptors targeting cancer
WO2017186121A1 (zh) * 2016-04-26 2017-11-02 科济生物医药(上海)有限公司 一种改善免疫应答细胞功能的方法
US20180100016A1 (en) * 2016-12-22 2018-04-12 Xiaotong Song Use of car-modified human natural killer cells to treat cancer
AU2018269194B2 (en) * 2017-05-15 2025-05-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Bicistronic chimeric antigen receptors and their uses

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