JPWO2021050534A5 - - Google Patents

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Publication number
JPWO2021050534A5
JPWO2021050534A5 JP2022515511A JP2022515511A JPWO2021050534A5 JP WO2021050534 A5 JPWO2021050534 A5 JP WO2021050534A5 JP 2022515511 A JP2022515511 A JP 2022515511A JP 2022515511 A JP2022515511 A JP 2022515511A JP WO2021050534 A5 JPWO2021050534 A5 JP WO2021050534A5
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JP
Japan
Prior art keywords
nucleic acid
crispr
seq
sequence
target nucleic
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Application number
JP2022515511A
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English (en)
Japanese (ja)
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JP2022547524A (ja
JP7705382B2 (ja
JP2022547524A5 (https=
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Priority claimed from PCT/US2020/049923 external-priority patent/WO2021050534A1/en
Publication of JP2022547524A publication Critical patent/JP2022547524A/ja
Publication of JPWO2021050534A5 publication Critical patent/JPWO2021050534A5/ja
Publication of JP2022547524A5 publication Critical patent/JP2022547524A5/ja
Priority to JP2025109210A priority Critical patent/JP2025161809A/ja
Application granted granted Critical
Publication of JP7705382B2 publication Critical patent/JP7705382B2/ja
Active legal-status Critical Current
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JP2022515511A 2019-09-09 2020-09-09 新規crispr dnaターゲティング酵素及びシステム Active JP7705382B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025109210A JP2025161809A (ja) 2019-09-09 2025-06-27 新規crispr dnaターゲティング酵素及びシステム

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962897859P 2019-09-09 2019-09-09
US62/897,859 2019-09-09
PCT/US2020/049923 WO2021050534A1 (en) 2019-09-09 2020-09-09 Novel crispr dna targeting enzymes and systems

Related Child Applications (1)

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JP2025109210A Division JP2025161809A (ja) 2019-09-09 2025-06-27 新規crispr dnaターゲティング酵素及びシステム

Publications (4)

Publication Number Publication Date
JP2022547524A JP2022547524A (ja) 2022-11-14
JPWO2021050534A5 true JPWO2021050534A5 (https=) 2023-09-15
JP2022547524A5 JP2022547524A5 (https=) 2023-09-15
JP7705382B2 JP7705382B2 (ja) 2025-07-09

Family

ID=74866391

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022515511A Active JP7705382B2 (ja) 2019-09-09 2020-09-09 新規crispr dnaターゲティング酵素及びシステム
JP2025109210A Pending JP2025161809A (ja) 2019-09-09 2025-06-27 新規crispr dnaターゲティング酵素及びシステム

Family Applications After (1)

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JP2025109210A Pending JP2025161809A (ja) 2019-09-09 2025-06-27 新規crispr dnaターゲティング酵素及びシステム

Country Status (11)

Country Link
US (5) US12460190B2 (https=)
EP (1) EP4028047A4 (https=)
JP (2) JP7705382B2 (https=)
KR (1) KR20220054434A (https=)
CN (1) CN114340657A (https=)
AU (1) AU2020347147A1 (https=)
CA (1) CA3150454A1 (https=)
IL (1) IL291095A (https=)
MX (1) MX2022002872A (https=)
WO (1) WO2021050534A1 (https=)
ZA (1) ZA202202628B (https=)

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AU2020347147A1 (en) 2019-09-09 2022-03-03 Arbor Biotechnologies, Inc. Novel CRISPR DNA targeting enzymes and systems
EP4081533A4 (en) * 2019-12-23 2024-03-20 The Regents of The University of California CRISPR-CAS EFFECTOR POLYPEPTIDES AND METHOD OF USE THEREOF
WO2022192381A1 (en) 2021-03-09 2022-09-15 Arbor Biotechnologies, Inc. Compositions comprising a variant polypeptide and uses thereof
US20240174997A1 (en) * 2021-03-09 2024-05-30 Arbor Biotechnologies, Inc. Compositions comprising a variant polypeptide and uses thereof
IL308806A (en) 2021-06-01 2024-01-01 Arbor Biotechnologies Inc Gene editing systems including nuclease crisper and their uses
WO2023250384A2 (en) * 2022-06-22 2023-12-28 The Regents Of The University Of California Crispr-cas effector polypeptides and methods of use thereof
WO2024020557A1 (en) * 2022-07-22 2024-01-25 Arbor Biotechnologies, Inc. Compositions comprising a variant nuclease and uses thereof
US20240035010A1 (en) * 2022-07-22 2024-02-01 Arbor Biotechnologies, Inc. Compositions comprising a variant polypeptide and uses thereof
CN117625578B (zh) * 2022-12-06 2024-12-27 山东舜丰生物科技有限公司 Crispr酶和系统及应用
WO2024173645A1 (en) 2023-02-15 2024-08-22 Arbor Biotechnologies, Inc. Gene editing method for inhibiting aberrant splicing in stathmin 2 (stmn2) transcript
WO2025006563A1 (en) 2023-06-26 2025-01-02 Arbor Biotechnologies, Inc. Gene editing systems targeting pcsk9 and uses thereof
WO2025171210A1 (en) 2024-02-09 2025-08-14 Arbor Biotechnologies, Inc. Compositions and methods for gene editing via homology-mediated end joining
WO2025212120A1 (en) 2024-04-05 2025-10-09 Arbor Biotechnologies, Inc. Chemical modifications of guide rnas for crispr nucleases
WO2026015829A2 (en) 2024-07-12 2026-01-15 Arbor Biotechnologies, Inc. Small reverse transcriptases and gene editing systems comprising such
WO2026015832A2 (en) 2024-07-12 2026-01-15 Arbor Biotechnologies, Inc. Reverse transcriptases and gene editing systems comprising such

Family Cites Families (20)

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US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5593972A (en) 1993-01-26 1997-01-14 The Wistar Institute Genetic immunization
US20040052799A1 (en) * 1996-11-15 2004-03-18 Astra Aktiebolag Nucleic acid and amino acid sequences relating to Helicobacter pylori for diagnostics and therapeutics
US20040216190A1 (en) 2003-04-28 2004-10-28 Kovalic David K. Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
JP4772045B2 (ja) 2004-07-16 2011-09-14 アメリカ合衆国 Cmv/r核酸コンストラクトを含むaidsに対するワクチン
US8703147B2 (en) 2007-11-05 2014-04-22 The Walter And Eliza Hall Institute Of Medical Research Methods and compositions for treating and preventing malaria (2)
EP4012714A1 (en) 2010-03-23 2022-06-15 Iogenetics, LLC. Bioinformatic processes for determination of peptide binding
EP2785370B1 (en) 2011-12-02 2021-07-21 Rhode Island Hospital Vaccine for falciparum malaria
AU2013359262C1 (en) 2012-12-12 2021-05-13 Massachusetts Institute Of Technology CRISPR-Cas component systems, methods and compositions for sequence manipulation
WO2016094872A1 (en) 2014-12-12 2016-06-16 The Broad Institute Inc. Dead guides for crispr transcription factors
WO2016094874A1 (en) 2014-12-12 2016-06-16 The Broad Institute Inc. Escorted and functionalized guides for crispr-cas systems
US20180187190A1 (en) * 2015-06-12 2018-07-05 Erasmus University Medical Center Rotterdam New crispr assays
US9790490B2 (en) 2015-06-18 2017-10-17 The Broad Institute Inc. CRISPR enzymes and systems
EP4159856A1 (en) 2015-06-18 2023-04-05 The Broad Institute, Inc. Novel crispr enzymes and systems
CN109153980B (zh) * 2015-10-22 2023-04-14 布罗德研究所有限公司 Vi-b型crispr酶和系统
US20200263190A1 (en) 2016-04-19 2020-08-20 The Broad Institute, Inc. Novel crispr enzymes and systems
US10125246B2 (en) * 2016-06-24 2018-11-13 King Fahd University Of Petroleum And Minerals Low density polyethylene (LDPE)-asphaltene composition and method of preparation
WO2018071672A1 (en) * 2016-10-12 2018-04-19 The Regents Of The University Of Colorado Novel engineered and chimeric nucleases
US11168322B2 (en) * 2017-06-30 2021-11-09 Arbor Biotechnologies, Inc. CRISPR RNA targeting enzymes and systems and uses thereof
AU2020347147A1 (en) 2019-09-09 2022-03-03 Arbor Biotechnologies, Inc. Novel CRISPR DNA targeting enzymes and systems

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