|
US6342390B1
(en)
|
1994-11-23 |
2002-01-29 |
The United States Of America As Represented By The Secretary Of Health And Human Services |
Lipid vesicles containing adeno-associated virus rep protein for transgene integration and gene therapy
|
|
US6093570A
(en)
|
1995-06-07 |
2000-07-25 |
The University Of North Carolina At Chapel Hill |
Helper virus-free AAV production
|
|
CA2265460A1
(en)
|
1996-09-11 |
1998-03-19 |
The Government Of The United States Of America, Represented By The Secre Tary, Department Of Health And Human Services |
Aav4 vector and uses thereof
|
|
US6995006B2
(en)
|
1997-09-05 |
2006-02-07 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
|
US6566118B1
(en)
|
1997-09-05 |
2003-05-20 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
|
US6642051B1
(en)
|
1997-10-21 |
2003-11-04 |
Targeted Genetics Corporation |
Amplifiable adeno-associated virus(AAV) packaging cassettes for the production of recombinant AAV vectors
|
|
IT1297074B1
(it)
|
1997-11-21 |
1999-08-03 |
Angeletti P Ist Richerche Bio |
Forme ormone-dipendenti delle proteine rep del virus adeno-associato (aav-2), sequenze di dna codificanti per esse, vettori che le
|
|
EP1082413B1
(en)
|
1998-05-28 |
2008-07-23 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
Aav5 vector and uses thereof
|
|
US6984517B1
(en)
|
1998-05-28 |
2006-01-10 |
The United States Of America As Represented By The Department Of Health And Human Services |
AAV5 vector and uses thereof
|
|
US6759237B1
(en)
|
1998-11-05 |
2004-07-06 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same
|
|
US6759050B1
(en)
|
1998-12-03 |
2004-07-06 |
Avigen, Inc. |
Excipients for use in adeno-associated virus pharmaceutical formulations, and pharmaceutical formulations made therewith
|
|
DE19905501B4
(de)
|
1999-02-10 |
2005-05-19 |
MediGene AG, Gesellschaft für molekularbiologische Kardiologie und Onkologie |
Verfahren zur Herstellung eines rekombinanten Adeno-assoziierten Virus, geeignete Mittel hierzu sowie Verwendung zur Herstellung eines Arzneimittels
|
|
US6498244B1
(en)
|
1999-05-28 |
2002-12-24 |
Cell Genesys, Inc. |
Adeno-associated virus capsid immunologic determinants
|
|
US7115391B1
(en)
|
1999-10-01 |
2006-10-03 |
Genovo, Inc. |
Production of recombinant AAV using adenovirus comprising AAV rep/cap genes
|
|
US7208315B2
(en)
|
2000-01-05 |
2007-04-24 |
Fred Hutchinson Cancer Research Center |
Compositions and methods for efficient AAV vector production
|
|
AU2002248297A1
(en)
|
2001-01-05 |
2002-07-16 |
Children's Hospital, Inc. |
Aav2 vectors and methods
|
|
US6841357B1
(en)
|
2001-03-30 |
2005-01-11 |
Stratagene California |
Method and kits for titering adeno-associated virus vectors
|
|
US6723551B2
(en)
|
2001-11-09 |
2004-04-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Production of adeno-associated virus in insect cells
|
|
WO2003042361A2
(en)
|
2001-11-09 |
2003-05-22 |
Government Of The United States Of America, Department Of Health And Human Services |
Production of adeno-associated virus in insect cells
|
|
NZ532635A
(en)
*
|
2001-11-13 |
2007-05-31 |
Univ Pennsylvania |
A method of identifying unknown adeno-associated virus (AAV) sequences and a kit for the method
|
|
DK2359869T3
(en)
|
2001-12-17 |
2019-04-15 |
Univ Pennsylvania |
Sequences of adeno-associated virus (AAV) serotype 8, vectors containing these, and uses thereof
|
|
US7419817B2
(en)
|
2002-05-17 |
2008-09-02 |
The United States Of America As Represented By The Secretary Department Of Health And Human Services, Nih. |
Scalable purification of AAV2, AAV4 or AAV5 using ion-exchange chromatography
|
|
US7122348B2
(en)
|
2002-12-11 |
2006-10-17 |
City Of Hope |
AAV2 Rep protein fusions
|
|
US9441244B2
(en)
|
2003-06-30 |
2016-09-13 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
US9233131B2
(en)
|
2003-06-30 |
2016-01-12 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
CN1856576B
(zh)
|
2003-09-30 |
2011-05-04 |
宾夕法尼亚州立大学托管会 |
腺伴随病毒(aav)进化支、序列、含有这些序列的载体及它们的应用
|
|
US7625570B1
(en)
|
2005-03-10 |
2009-12-01 |
The Regents Of The University Of California |
Methods for purifying adeno-associated virus
|
|
EP2311967B1
(en)
|
2005-10-20 |
2017-09-20 |
UniQure IP B.V. |
Improved AAV vectors produced in insect cells
|
|
ES2385679T3
(es)
|
2006-08-24 |
2012-07-30 |
Virovek, Inc. |
Expresión de células de insecto de genes con marcos de lectura abiertos superpuestos, métodos y composiciones de éstos
|
|
WO2010022195A2
(en)
|
2008-08-20 |
2010-02-25 |
Virxsys Corporation |
Non-integrating lenti/adeno-associated virus hybrid vector system
|
|
HUE028341T2
(en)
|
2009-06-16 |
2016-12-28 |
Genzyme Corp |
Improved methods for purification of recombinant aav vectors
|
|
JP2014503173A
(ja)
*
|
2009-11-05 |
2014-02-13 |
プロイェクト、デ、ビオメディシナ、シーマ、ソシエダッド、リミターダ |
制御された発現系
|
|
US8663624B2
(en)
|
2010-10-06 |
2014-03-04 |
The Regents Of The University Of California |
Adeno-associated virus virions with variant capsid and methods of use thereof
|
|
DK2675902T3
(da)
|
2011-02-17 |
2019-06-03 |
Univ Pennsylvania |
Sammensætninger og fremgangsmåder til at ændre vævsspecificitet og forbedre aav9-medieret genoverførsel
|
|
EP2500434A1
(en)
|
2011-03-12 |
2012-09-19 |
Association Institut de Myologie |
Capsid-free AAV vectors, compositions, and methods for vector production and gene delivery
|
|
WO2012145509A2
(en)
|
2011-04-19 |
2012-10-26 |
The Research Foundation Of State University Of New York |
Adeno-associated-virus rep sequences, vectors, and viruses
|
|
HRP20171334T1
(hr)
|
2011-04-22 |
2017-11-17 |
The Regents Of The University Of California |
Virioni adeno-povezanog virusa s kapsid varijantom i postupci njihove upotrebe
|
|
US9441206B2
(en)
|
2011-10-28 |
2016-09-13 |
The University Of North Carolina At Chapel Hill |
Cell line for production of adeno-associated virus
|
|
EP3241902B1
(en)
|
2012-05-25 |
2018-02-28 |
The Regents of The University of California |
Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription
|
|
US8697359B1
(en)
|
2012-12-12 |
2014-04-15 |
The Broad Institute, Inc. |
CRISPR-Cas systems and methods for altering expression of gene products
|
|
US10106816B2
(en)
*
|
2012-12-14 |
2018-10-23 |
Case Western Reserve University |
Genomic RNA packaging enhancer element
|
|
US9447433B2
(en)
|
2013-03-15 |
2016-09-20 |
The University Of North Carolina At Chapel Hill |
Synthetic adeno-associated virus inverted terminal repeats
|
|
CN105765066B
(zh)
|
2013-11-29 |
2018-12-14 |
宝生物工程株式会社 |
用于定量腺伴随病毒的方法
|
|
GB201407852D0
(en)
*
|
2014-05-02 |
2014-06-18 |
Iontas Ltd |
Preparation of libraries od protein variants expressed in eukaryotic cells and use for selecting binding molecules
|
|
JP7023842B2
(ja)
*
|
2015-10-29 |
2022-02-22 |
テンプル ユニヴァーシティ - オブ ザ コモンウェルス システム オブ ハイアー エデュケーション |
Dnaポリメラーゼシータによる核酸の3’末端の修飾
|
|
US11208630B2
(en)
|
2015-12-24 |
2021-12-28 |
University Of Florida Research Foundation, Incorporated |
AAV production using suspension adapted cells
|
|
CA3012409A1
(en)
*
|
2016-01-29 |
2017-08-03 |
Sirion Biotech Gmbh |
Aav-based conditional expression system
|
|
JP7632835B2
(ja)
*
|
2016-05-20 |
2025-02-19 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
加齢関連疾患及び症状の遺伝子治療法
|
|
US10294452B2
(en)
|
2016-11-22 |
2019-05-21 |
Dao-Yao He |
Lysis, extraction and purification of adeno-associated virus and adenovirus from host cells
|
|
CN108727486A
(zh)
*
|
2017-04-24 |
2018-11-02 |
舒泰神(北京)生物制药股份有限公司 |
长效神经生长因子、制备方法及其组合物
|
|
US10653731B1
(en)
|
2019-07-15 |
2020-05-19 |
Vigene Biosciences Inc. |
Recombinantly-modified adeno-associated virus (rAAV) having improved packaging efficiency
|