JPWO2020252136A5 - - Google Patents
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- Publication number
- JPWO2020252136A5 JPWO2020252136A5 JP2021573442A JP2021573442A JPWO2020252136A5 JP WO2020252136 A5 JPWO2020252136 A5 JP WO2020252136A5 JP 2021573442 A JP2021573442 A JP 2021573442A JP 2021573442 A JP2021573442 A JP 2021573442A JP WO2020252136 A5 JPWO2020252136 A5 JP WO2020252136A5
- Authority
- JP
- Japan
- Prior art keywords
- vector
- raav vector
- raav
- promoter
- plasma kallikrein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962860101P | 2019-06-11 | 2019-06-11 | |
| US62/860,101 | 2019-06-11 | ||
| PCT/US2020/037189 WO2020252136A1 (en) | 2019-06-11 | 2020-06-11 | Adeno associated viral vector delivery of antibodies for the treatment of disease mediated dysregulated plasma kallikrein |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022536692A JP2022536692A (ja) | 2022-08-18 |
| JPWO2020252136A5 true JPWO2020252136A5 (https=) | 2023-06-20 |
| JP2022536692A5 JP2022536692A5 (https=) | 2023-06-20 |
Family
ID=71995023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021573442A Pending JP2022536692A (ja) | 2019-06-11 | 2020-06-11 | 調節不全の血漿カリクレインによって媒介される疾患の治療のための抗体のアデノ随伴ウイルスベクター送達 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230038502A1 (https=) |
| EP (1) | EP3983449A1 (https=) |
| JP (1) | JP2022536692A (https=) |
| CN (1) | CN114207135A (https=) |
| AR (1) | AR119271A1 (https=) |
| TW (1) | TW202115126A (https=) |
| WO (1) | WO2020252136A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021120890A1 (en) * | 2019-12-20 | 2021-06-24 | Novartis Ag | Pyrazolyl derivatives useful as anti-cancer agents |
| EP4213890A1 (en) * | 2020-09-15 | 2023-07-26 | RegenxBio Inc. | Vectorized lanadelumab and administration thereof |
| CA3094859A1 (en) * | 2020-10-01 | 2022-04-01 | Entos Pharmaceuticals Inc. | Proteolipid vesicles formulated with fusion associated small transmembrane proteins |
| CN114790245A (zh) * | 2021-01-25 | 2022-07-26 | 成都康弘生物科技有限公司 | 一种抗体及其用途 |
| KR20230137410A (ko) * | 2021-01-28 | 2023-10-04 | 아스트리아 테라퓨틱스, 인크. | 혈장 칼리크레인 항체 및 이의 용도 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6136597A (en) | 1997-09-18 | 2000-10-24 | The Salk Institute For Biological Studies | RNA export element |
| US7419829B2 (en) | 2000-10-06 | 2008-09-02 | Oxford Biomedica (Uk) Limited | Vector system |
| US7575924B2 (en) | 2000-11-13 | 2009-08-18 | Research Development Foundation | Methods and compositions relating to improved lentiviral vectors and their applications |
| EP1438075A4 (en) | 2001-10-02 | 2006-04-19 | Inst Clayton De La Rech | METHOD AND COMPOSITIONS ASSOCIATED WITH LENTIVIRAL VECTORS WITH LIMITED EXPRESSION AND ITS APPLICATIONS |
| US7816131B2 (en) | 2004-04-02 | 2010-10-19 | Board Of Regents, The University Of Texas System | Cancer specific promoters |
| US9725485B2 (en) * | 2012-05-15 | 2017-08-08 | University Of Florida Research Foundation, Inc. | AAV vectors with high transduction efficiency and uses thereof for gene therapy |
| US8865881B2 (en) | 2011-02-22 | 2014-10-21 | California Institute Of Technology | Delivery of proteins using adeno-associated virus (AAV) vectors |
| GB201206455D0 (en) | 2012-04-12 | 2012-05-30 | Royal Holloway & Bedford New College | Gene expression |
| CA2876285A1 (en) * | 2012-08-08 | 2014-02-13 | Roche Glycart Ag | Interleukin-10 fusion proteins and uses thereof |
| JP2016517440A (ja) | 2013-03-15 | 2016-06-16 | ブイエルピー バイオテック，インコーポレイテッド | パリビズマブエピトープベースのウイルス様粒子 |
| WO2014152232A2 (en) | 2013-03-15 | 2014-09-25 | Dyax Corp. | Anti-plasma kallikrein antibodies |
| IL295414B2 (en) * | 2014-03-27 | 2026-02-01 | Takeda Pharmaceuticals Co | Compositions and methods for treating macular edema due to diabetes |
| US20160130324A1 (en) * | 2014-10-31 | 2016-05-12 | Shire Human Genetic Therapies, Inc. | C1 Inhibitor Fusion Proteins and Uses Thereof |
| CN107249646B (zh) | 2014-12-16 | 2021-06-29 | 内布拉斯加大学董事会 | 用于青少年巴滕病的基因疗法 |
| CL2014003590A1 (es) | 2014-12-30 | 2015-07-10 | Univ Chile | Virus aav/xbp1s-ha, método de tratamiento genético y su uso en la optimizacion y mejoramiento de las capacidades cognitivas, de memoria y de aprendizaje. |
| MA41346A (fr) | 2015-01-12 | 2017-11-21 | Juno Therapeutics Inc | Eléments régulateurs post-transcriptionnels d'hépatite modifiée |
| EP3270944B1 (en) * | 2015-03-17 | 2019-10-23 | Vrije Universiteit Brussel | Optimized liver-specific expression systems for fviii and fix |
| US10179918B2 (en) | 2015-05-07 | 2019-01-15 | Sangamo Therapeutics, Inc. | Methods and compositions for increasing transgene activity |
| GB2547179A (en) | 2015-10-26 | 2017-08-16 | Quethera Ltd | Genetic construct |
| CN108291238A (zh) | 2015-10-27 | 2018-07-17 | 赛尔希恩公司 | 嵌合转录后调控元件 |
| CN109415687A (zh) | 2016-04-07 | 2019-03-01 | 蓝鸟生物公司 | 嵌合抗原受体t细胞组合物 |
| JP7632835B2 (ja) | 2016-05-20 | 2025-02-19 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 加齢関連疾患及び症状の遺伝子治療法 |
| CN110662839A (zh) | 2017-02-17 | 2020-01-07 | 珀杜研究基金会 | 用于细胞疗法的基于靶向性配体-有效负载的药物递送 |
| CN110945127B (zh) * | 2017-05-22 | 2024-07-12 | 武田药品工业株式会社 | 用于血友病b的基因疗法的编码具有增加的表达的重组fix的病毒载体 |
| BR112020007405A2 (pt) * | 2017-10-18 | 2020-12-08 | Regenxbio Inc. | Produtos terapêuticos de anticorpo pós-translacionalmente modificados totalmente humanos |
-
2020
- 2020-06-11 US US17/618,193 patent/US20230038502A1/en not_active Abandoned
- 2020-06-11 CN CN202080055596.9A patent/CN114207135A/zh active Pending
- 2020-06-11 AR ARP200101656A patent/AR119271A1/es unknown
- 2020-06-11 WO PCT/US2020/037189 patent/WO2020252136A1/en not_active Ceased
- 2020-06-11 JP JP2021573442A patent/JP2022536692A/ja active Pending
- 2020-06-11 TW TW109119759A patent/TW202115126A/zh unknown
- 2020-06-11 EP EP20753482.7A patent/EP3983449A1/en active Pending
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