JPWO2020235283A1 - - Google Patents
Info
- Publication number
- JPWO2020235283A1 JPWO2020235283A1 JP2021520664A JP2021520664A JPWO2020235283A1 JP WO2020235283 A1 JPWO2020235283 A1 JP WO2020235283A1 JP 2021520664 A JP2021520664 A JP 2021520664A JP 2021520664 A JP2021520664 A JP 2021520664A JP WO2020235283 A1 JPWO2020235283 A1 JP WO2020235283A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/59—Transmissivity
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44782—Apparatus specially adapted therefor of a plurality of samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
- G01N2021/6421—Measuring at two or more wavelengths
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
- G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
- G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Sustainable Development (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023081433A JP7608515B2 (ja) | 2019-05-22 | 2023-05-17 | 分析装置および分析方法 |
| JP2024222003A JP7834157B2 (ja) | 2019-05-22 | 2024-12-18 | マルチキャピラリ電気泳動装置 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019096011 | 2019-05-22 | ||
| JP2019096011 | 2019-05-22 | ||
| PCT/JP2020/017202 WO2020235283A1 (ja) | 2019-05-22 | 2020-04-21 | 分析装置および分析方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023081433A Division JP7608515B2 (ja) | 2019-05-22 | 2023-05-17 | 分析装置および分析方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2020235283A1 true JPWO2020235283A1 (https=) | 2020-11-26 |
| JPWO2020235283A5 JPWO2020235283A5 (https=) | 2022-03-16 |
| JP7282880B2 JP7282880B2 (ja) | 2023-05-29 |
Family
ID=73458607
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021520664A Active JP7282880B2 (ja) | 2019-05-22 | 2020-04-21 | 分析装置および分析方法 |
| JP2023081433A Active JP7608515B2 (ja) | 2019-05-22 | 2023-05-17 | 分析装置および分析方法 |
| JP2024222003A Active JP7834157B2 (ja) | 2019-05-22 | 2024-12-18 | マルチキャピラリ電気泳動装置 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023081433A Active JP7608515B2 (ja) | 2019-05-22 | 2023-05-17 | 分析装置および分析方法 |
| JP2024222003A Active JP7834157B2 (ja) | 2019-05-22 | 2024-12-18 | マルチキャピラリ電気泳動装置 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US12276608B2 (https=) |
| JP (3) | JP7282880B2 (https=) |
| CN (5) | CN119310164A (https=) |
| DE (1) | DE112020002033T5 (https=) |
| GB (5) | GB2619178B (https=) |
| SG (1) | SG11202112784UA (https=) |
| WO (1) | WO2020235283A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2619178B (en) * | 2019-05-22 | 2024-05-01 | Hitachi High Tech Corp | Analysis device and analysis method |
| CN114527105B (zh) * | 2022-02-23 | 2025-08-22 | 上海交通大学 | 一种定量分析多种荧光物质成分的高精度通用方法 |
| WO2025042409A1 (en) * | 2023-08-18 | 2025-02-27 | Rarecyte, Inc. | Methods of reducing spectral crosstalk in multiplexed fluorescence imaging |
| US12038381B1 (en) | 2023-08-18 | 2024-07-16 | Rarecyte, Inc. | Methods of reducing spectral crosstalk in multiplexed fluorescence imaging |
| DE112023005372T5 (de) * | 2023-08-24 | 2025-10-09 | Hitachi High-Tech Corporation | Lichterfassungsvorrichtung und signalverarbeitungsverfahren |
| CN119861055B (zh) * | 2024-12-05 | 2025-11-25 | 公安部第一研究所 | 一种dna荧光光谱串扰修正的方法及系统 |
Citations (5)
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| JP2004532969A (ja) * | 2000-10-12 | 2004-10-28 | アムニス コーポレイション | レポーターラベルビードを読み取るための方法および装置 |
| JP2005524051A (ja) * | 2001-08-28 | 2005-08-11 | ベイラー カレッジ オブ メディスン | カラーブラインド蛍光のためのパルスマルチライン励起法 |
| JP2006515428A (ja) * | 2003-02-27 | 2006-05-25 | コンビセップ インコーポレーテッド | 電気泳動計器のためのロボットフレンドリな外部ローディングシステムおよび方法 |
| US20140303016A1 (en) * | 2007-06-06 | 2014-10-09 | Pacific Biosciences Of California, Inc. | Methods and Processes for Calling Bases in Sequence by Incorporation Methods |
| WO2018151843A2 (en) * | 2017-02-17 | 2018-08-23 | Life Technologies Corporation | Automated quality control and spectral error correction for sample analysis instruments |
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| US5096807A (en) * | 1985-03-06 | 1992-03-17 | Murex Corporation | Imaging immunoassay detection system with background compensation and its use |
| JPS62260652A (ja) | 1985-12-27 | 1987-11-12 | コニカ株式会社 | 写真処理液容器 |
| WO2000055882A1 (en) * | 1999-03-18 | 2000-09-21 | Cambridge Research & Instrumentation Inc. | High-efficiency multiple probe imaging system |
| JP4175735B2 (ja) * | 1999-05-12 | 2008-11-05 | 独立行政法人理化学研究所 | マルチキャピラリー電気泳動装置 |
| EP1354193B1 (en) * | 2001-01-26 | 2007-06-06 | Biocal Technology, Inc. | Optical detection in a multi-channel bio-separation system |
| JP3897277B2 (ja) | 2001-04-02 | 2007-03-22 | 株式会社日立製作所 | キャピラリアレイ及びキャピラリアレイ光検出装置 |
| AU2002308693A1 (en) * | 2001-04-25 | 2002-11-05 | Amnis Corporation | Method and apparatus for correcting crosstalk and spatial resolution for multichannel imaging |
| US7222059B2 (en) * | 2001-11-15 | 2007-05-22 | Siemens Medical Solutions Diagnostics | Electrophoretic trace simulator |
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| WO2006015251A2 (en) * | 2004-07-29 | 2006-02-09 | The Research Foundation Of State University Of New York | System and method for cross-talk cancellation in a multilane fluorescence detector |
| US20060094109A1 (en) * | 2004-11-02 | 2006-05-04 | Immunivest Corporation | Device and method for analytical cell imaging |
| US7715001B2 (en) * | 2006-02-13 | 2010-05-11 | Pacific Biosciences Of California, Inc. | Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources |
| US7692783B2 (en) * | 2006-02-13 | 2010-04-06 | Pacific Biosciences Of California | Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources |
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| JP4964568B2 (ja) * | 2006-11-24 | 2012-07-04 | 浜松ホトニクス株式会社 | 蛍光検出装置、蛍光検出方法および蛍光検出プログラム |
| US8182993B2 (en) * | 2007-06-06 | 2012-05-22 | Pacific Biosciences Of California, Inc. | Methods and processes for calling bases in sequence by incorporation methods |
| US8475640B2 (en) | 2009-04-20 | 2013-07-02 | Advanced Analytical Technologies, Inc. | Method for multiplexed capillary electrophoresis signal cross-talk correction |
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| US20120015825A1 (en) * | 2010-07-06 | 2012-01-19 | Pacific Biosciences Of California, Inc. | Analytical systems and methods with software mask |
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| US9170198B2 (en) * | 2013-12-19 | 2015-10-27 | Luminex Corporation | Crosstalk reduction |
| DE112015005826B4 (de) * | 2015-01-27 | 2023-01-26 | Hitachi High-Tech Corporation | Mehrfarbige-fluoreszenz-analysevorrichtung |
| JP6975704B2 (ja) * | 2015-02-03 | 2021-12-01 | 株式会社日立ハイテク | 多色検出装置 |
| JP6456983B2 (ja) | 2015-02-03 | 2019-01-23 | 株式会社日立ハイテクノロジーズ | 多色検出装置 |
| EP3147650A1 (en) * | 2015-09-22 | 2017-03-29 | MyCartis N.V. | Cross-talk correction in multiplexing analysis of biological sample |
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| US11210554B2 (en) * | 2019-03-21 | 2021-12-28 | Illumina, Inc. | Artificial intelligence-based generation of sequencing metadata |
| US11593649B2 (en) * | 2019-05-16 | 2023-02-28 | Illumina, Inc. | Base calling using convolutions |
| GB2619178B (en) * | 2019-05-22 | 2024-05-01 | Hitachi High Tech Corp | Analysis device and analysis method |
| US11237111B2 (en) * | 2020-01-30 | 2022-02-01 | Trustees Of Boston University | High-speed delay scanning and deep learning techniques for spectroscopic SRS imaging |
| DE112020006681T5 (de) * | 2020-04-16 | 2022-12-01 | Hitachi High-Tech Corporation | Elektrophoresesystem |
| DE112023005372T5 (de) * | 2023-08-24 | 2025-10-09 | Hitachi High-Tech Corporation | Lichterfassungsvorrichtung und signalverarbeitungsverfahren |
-
2020
- 2020-04-21 GB GB2312065.2A patent/GB2619178B/en active Active
- 2020-04-21 WO PCT/JP2020/017202 patent/WO2020235283A1/ja not_active Ceased
- 2020-04-21 CN CN202411307788.0A patent/CN119310164A/zh active Pending
- 2020-04-21 CN CN202411307797.XA patent/CN119310167A/zh active Pending
- 2020-04-21 GB GB2312063.7A patent/GB2619177B/en active Active
- 2020-04-21 GB GB2116497.5A patent/GB2597202B/en active Active
- 2020-04-21 GB GB2311980.3A patent/GB2619176B/en active Active
- 2020-04-21 CN CN202411307793.1A patent/CN119310166A/zh active Pending
- 2020-04-21 CN CN202411307791.2A patent/CN119310165A/zh active Pending
- 2020-04-21 US US17/612,046 patent/US12276608B2/en active Active
- 2020-04-21 JP JP2021520664A patent/JP7282880B2/ja active Active
- 2020-04-21 DE DE112020002033.9T patent/DE112020002033T5/de active Pending
- 2020-04-21 CN CN202080036799.3A patent/CN113840902B/zh active Active
- 2020-04-21 GB GB2312067.8A patent/GB2619179B/en active Active
- 2020-04-21 SG SG11202112784UA patent/SG11202112784UA/en unknown
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2023
- 2023-05-17 JP JP2023081433A patent/JP7608515B2/ja active Active
-
2024
- 2024-12-18 JP JP2024222003A patent/JP7834157B2/ja active Active
-
2025
- 2025-03-11 US US19/076,669 patent/US20250271360A1/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004532969A (ja) * | 2000-10-12 | 2004-10-28 | アムニス コーポレイション | レポーターラベルビードを読み取るための方法および装置 |
| JP2005524051A (ja) * | 2001-08-28 | 2005-08-11 | ベイラー カレッジ オブ メディスン | カラーブラインド蛍光のためのパルスマルチライン励起法 |
| JP2006515428A (ja) * | 2003-02-27 | 2006-05-25 | コンビセップ インコーポレーテッド | 電気泳動計器のためのロボットフレンドリな外部ローディングシステムおよび方法 |
| US20140303016A1 (en) * | 2007-06-06 | 2014-10-09 | Pacific Biosciences Of California, Inc. | Methods and Processes for Calling Bases in Sequence by Incorporation Methods |
| WO2018151843A2 (en) * | 2017-02-17 | 2018-08-23 | Life Technologies Corporation | Automated quality control and spectral error correction for sample analysis instruments |
Non-Patent Citations (1)
| Title |
|---|
| YANG T H, ET AL.: "Comparative microRNA detection from precursor-microRNA-transfected hepatocellular carcinoma cells by", ELECTROPHORESIS, vol. 33, JPN6020024999, September 2012 (2012-09-01), pages 2769 - 2776, ISSN: 0004921224 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP7282880B2 (ja) | 2023-05-29 |
| GB2619179A (en) | 2023-11-29 |
| GB202312063D0 (en) | 2023-09-20 |
| GB202312065D0 (en) | 2023-09-20 |
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