JPWO2020225363A5 - - Google Patents

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Publication number
JPWO2020225363A5
JPWO2020225363A5 JP2021566142A JP2021566142A JPWO2020225363A5 JP WO2020225363 A5 JPWO2020225363 A5 JP WO2020225363A5 JP 2021566142 A JP2021566142 A JP 2021566142A JP 2021566142 A JP2021566142 A JP 2021566142A JP WO2020225363 A5 JPWO2020225363 A5 JP WO2020225363A5
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JP
Japan
Prior art keywords
binding site
ligand
raav
ligand binding
particle
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JP2021566142A
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English (en)
Japanese (ja)
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JP2022531892A5 (https=
JP7737312B2 (ja
JP2022531892A (ja
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Priority claimed from EP19173365.8A external-priority patent/EP3736330A1/en
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Publication of JPWO2020225363A5 publication Critical patent/JPWO2020225363A5/ja
Publication of JP2022531892A5 publication Critical patent/JP2022531892A5/ja
Priority to JP2025077923A priority Critical patent/JP2025121993A/ja
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JP2021566142A 2019-05-08 2020-05-07 遺伝子治療のための改変型アデノ随伴ウイルス （ａａｖ） 粒子 Active JP7737312B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025077923A JP2025121993A (ja) 2019-05-08 2025-05-08 遺伝子治療のための改変型アデノ随伴ウイルス （ａａｖ） 粒子

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19173365.8 2019-05-08
EP19173365.8A EP3736330A1 (en) 2019-05-08 2019-05-08 Modified adeno-associated virus (aav) particles for gene therapy
PCT/EP2020/062713 WO2020225363A2 (en) 2019-05-08 2020-05-07 Modified adeno-associated virus (aav) particles for gene therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025077923A Division JP2025121993A (ja) 2019-05-08 2025-05-08 遺伝子治療のための改変型アデノ随伴ウイルス （ａａｖ） 粒子

Publications (4)

Publication Number Publication Date
JP2022531892A JP2022531892A (ja) 2022-07-12
JPWO2020225363A5 true JPWO2020225363A5 (https=) 2023-05-15
JP2022531892A5 JP2022531892A5 (https=) 2023-05-15
JP7737312B2 JP7737312B2 (ja) 2025-09-10

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ID=66483846

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021566142A Active JP7737312B2 (ja) 2019-05-08 2020-05-07 遺伝子治療のための改変型アデノ随伴ウイルス （ａａｖ） 粒子
JP2025077923A Withdrawn JP2025121993A (ja) 2019-05-08 2025-05-08 遺伝子治療のための改変型アデノ随伴ウイルス （ａａｖ） 粒子

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025077923A Withdrawn JP2025121993A (ja) 2019-05-08 2025-05-08 遺伝子治療のための改変型アデノ随伴ウイルス （ａａｖ） 粒子

Country Status (12)

Country Link
US (1) US20220288234A1 (https=)
EP (2) EP3736330A1 (https=)
JP (2) JP7737312B2 (https=)
KR (1) KR20220008863A (https=)
CN (1) CN114008194A (https=)
AU (1) AU2020268759A1 (https=)
BR (1) BR112021022385A2 (https=)
CA (1) CA3139183A1 (https=)
IL (1) IL287614A (https=)
MX (1) MX2021013619A (https=)
SG (1) SG11202112029XA (https=)
WO (1) WO2020225363A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3201533A1 (en) 2020-11-11 2022-05-19 European Molecular Biology Laboratory Modified viral particles for gene therapy
CN118109515A (zh) * 2022-11-29 2024-05-31 中国科学院深圳先进技术研究院 一种基于生物正交技术的病毒载体及其制备方法和应用
CN121889172A (zh) 2023-07-21 2026-04-17 意大利商博雷亚医疗有限责任公司 制备表面修饰病毒衣壳的方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797368A (en) 1985-03-15 1989-01-10 The United States Of America As Represented By The Department Of Health And Human Services Adeno-associated virus as eukaryotic expression vector
US5139941A (en) 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
US5173414A (en) 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
US5252479A (en) 1991-11-08 1993-10-12 Research Corporation Technologies, Inc. Safe vector for gene therapy
US5756283A (en) 1995-06-05 1998-05-26 The Trustees Of The University Of Pennsylvania Method for improved production of recombinant adeno-associated viruses for gene therapy
EP1486567A1 (en) 2003-06-11 2004-12-15 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Improved adeno-associated virus (AAV) vector for gene therapy
KR102437522B1 (ko) 2012-05-25 2022-08-26 셀렉티스 면역요법을 위한 동종이형 및 면역억제제 저항성인 ｔ 세포의 조작 방법
KR102234672B1 (ko) * 2013-05-21 2021-04-06 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 캡시드-변형된 raav3 벡터 조성물, 및 인간 간암의 유전자 요법에서의 용도
WO2014191128A1 (en) 2013-05-29 2014-12-04 Cellectis Methods for engineering t cells for immunotherapy by using rna-guided cas nuclease system
CN104592364B (zh) * 2013-10-30 2018-05-01 北京大学 定点突变和定点修饰的腺相关病毒、其制备方法及应用
US10179176B2 (en) 2016-02-16 2019-01-15 The Board Of Trustees Of The Leland Stanford Junior University Recombinant adeno-associated virus capsids resistant to pre-existing human neutralizing antibodies
EP3448875A4 (en) * 2016-04-29 2020-04-08 Voyager Therapeutics, Inc. COMPOSITIONS FOR TREATING A DISEASE
FI3445773T3 (fi) * 2016-05-13 2023-03-30 4D Molecular Therapeutics Inc Adenoassosioituneen viruksen kapsidimuunnoksia ja niiden käyttömenetelmiä
WO2018035503A1 (en) * 2016-08-18 2018-02-22 The Regents Of The University Of California Crispr-cas genome engineering via a modular aav delivery system
MX2020000244A (es) * 2017-06-27 2020-09-28 Regeneron Pharma Vectores virales recombinantes con tropismo modificado y usos de estos para la introduccion dirigida de material genetico a celulas humanas.
EP3461836A1 (en) * 2017-09-28 2019-04-03 Universität zu Köln Mutated adeno-associated viral capsid proteins for chemical coupling of ligands, nanoparticles or drugs via thioether binding and production method thereof

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