JPWO2020180501A5 - - Google Patents
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- JPWO2020180501A5 JPWO2020180501A5 JP2021543384A JP2021543384A JPWO2020180501A5 JP WO2020180501 A5 JPWO2020180501 A5 JP WO2020180501A5 JP 2021543384 A JP2021543384 A JP 2021543384A JP 2021543384 A JP2021543384 A JP 2021543384A JP WO2020180501 A5 JPWO2020180501 A5 JP WO2020180501A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- amino acid
- acid sequence
- mhc class
- presenting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962814715P | 2019-03-06 | 2019-03-06 | |
| US62/814,715 | 2019-03-06 | ||
| PCT/US2020/019244 WO2020180501A1 (en) | 2019-03-06 | 2020-02-21 | T-cell modulatory antigen-presenting polypeptides and methods of use thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022522404A JP2022522404A (ja) | 2022-04-19 |
| JPWO2020180501A5 true JPWO2020180501A5 (https=) | 2023-03-01 |
| JP2022522404A5 JP2022522404A5 (https=) | 2023-03-01 |
| JP7691927B2 JP7691927B2 (ja) | 2025-06-12 |
Family
ID=72338064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021543384A Active JP7691927B2 (ja) | 2019-03-06 | 2020-02-21 | T細胞調節抗原提示ポリペプチド及びその使用方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20220106378A1 (https=) |
| EP (1) | EP3935079A4 (https=) |
| JP (1) | JP7691927B2 (https=) |
| WO (1) | WO2020180501A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116970059A (zh) | 2016-12-22 | 2023-10-31 | 库尔生物制药有限公司 | T细胞调节性多聚体多肽及其使用方法 |
| IL269000B2 (en) | 2017-03-15 | 2024-06-01 | Cue Biopharma Inc | Methods for modulating an immune response |
| CA3061614A1 (en) | 2017-04-28 | 2018-11-01 | The Regents Of The University Of Colorado, A Body Corporate | Methods of treating rheumatoid arthritis using rna-guided genome editing of hla gene |
| TW201920249A (zh) | 2017-09-07 | 2019-06-01 | 美商信號生物製藥公司 | 具有結合位點之t細胞調節多聚體多肽及其使用方法 |
| TW202208395A (zh) | 2020-05-12 | 2022-03-01 | 美商信號生物製藥公司 | 多聚體t細胞調節多肽及其使用方法 |
| JP2024517658A (ja) * | 2021-04-21 | 2024-04-23 | キュー バイオファーマ, インコーポレイテッド | 1型真性糖尿病(t1d)を治療するためのmhcクラスii t細胞調節ポリペプチド及びその使用方法 |
| CN117561280A (zh) * | 2021-04-21 | 2024-02-13 | 库尔生物制药有限公司 | 携带TGF-β的抗原呈递多肽复合物及其使用方法 |
| CN117396229A (zh) * | 2021-04-21 | 2024-01-12 | Cue生物制药股份有限公司 | Mhc ii类t细胞调节多肽及其使用方法 |
| JP2024517475A (ja) * | 2021-05-10 | 2024-04-22 | ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド,ア ボディー コーポレイト | 自己免疫を治療するための操作されたhla対立遺伝子 |
| US20240270815A1 (en) * | 2021-05-26 | 2024-08-15 | Cue Biopharma, Inc. | Antigen Presenting Polypeptide Complexes and Methods of Use Thereof |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| JP3534749B2 (ja) | 1991-08-20 | 2004-06-07 | アメリカ合衆国 | アデノウイルスが介在する胃腸管への遺伝子の輸送 |
| US5252479A (en) | 1991-11-08 | 1993-10-12 | Research Corporation Technologies, Inc. | Safe vector for gene therapy |
| FR2688514A1 (fr) | 1992-03-16 | 1993-09-17 | Centre Nat Rech Scient | Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant. |
| AU680459B2 (en) | 1992-12-03 | 1997-07-31 | Genzyme Corporation | Gene therapy for cystic fibrosis |
| ES2249761T3 (es) | 1993-06-24 | 2006-04-01 | Advec Inc. | Vectores de adenovirus para terapia genica. |
| EP1637608B1 (en) | 1993-10-25 | 2009-07-22 | CANJI, Inc. | Recombinant adenoviral vector and methods of use |
| JPH10503379A (ja) * | 1994-07-29 | 1998-03-31 | デイド・インターナショナル・インコーポレーテッド | Mhc複合体およびその用途 |
| US7078387B1 (en) | 1998-12-28 | 2006-07-18 | Arch Development Corp. | Efficient and stable in vivo gene transfer to cardiomyocytes using recombinant adeno-associated virus vectors |
| US6287860B1 (en) | 2000-01-20 | 2001-09-11 | Isis Pharmaceuticals, Inc. | Antisense inhibition of MEKK2 expression |
| US6811785B2 (en) | 2001-05-07 | 2004-11-02 | Mount Sinai School Of Medicine Of New York University | Multivalent MHC class II—peptide chimeras |
| WO2003062370A2 (en) | 2001-07-19 | 2003-07-31 | Perlan Therapeutics, Inc. | Multimeric proteins and methods of making and using same |
| US10105437B2 (en) | 2004-04-28 | 2018-10-23 | Btg International Limited | Epitopes related to coeliac disease |
| US7855279B2 (en) | 2005-09-27 | 2010-12-21 | Amunix Operating, Inc. | Unstructured recombinant polymers and uses thereof |
| EP1996937A4 (en) | 2006-03-06 | 2009-04-08 | Amunix Inc | GENETIC PACKS AND USES THEREOF |
| US8933197B2 (en) | 2007-08-15 | 2015-01-13 | Amunix Operating Inc. | Compositions comprising modified biologically active polypeptides |
| CA2748314C (en) | 2009-02-03 | 2018-10-02 | Amunix Operating Inc. | Extended recombinant polypeptides and compositions comprising same |
| WO2012007951A1 (en) * | 2010-07-15 | 2012-01-19 | Technion Research & Development Foundation Ltd. | Isolated high affinity entities with t-cell receptor like specificity towards native complexes of mhc class ii and glutamic acid decarboxylase (gad) autoantigenic peptides |
| US10816554B2 (en) * | 2014-04-04 | 2020-10-27 | The Board Of Trustees Of The Leland Stanford Junior University | Ligand discovery for T cell receptors |
| WO2015164714A1 (en) | 2014-04-24 | 2015-10-29 | Immusant, Inc. | Use of interleukin-2 for diagnosis of celiac disease |
| PL3157552T3 (pl) | 2014-06-18 | 2020-05-18 | Albert Einstein College Of Medicine | Polipeptydy syntac i ich zastosowania |
| RS59340B1 (sr) * | 2014-11-06 | 2019-10-31 | Hoffmann La Roche | Varijante fc regiona sa modifikovanim vezivanjem za fcrn i metode upotrebe |
| ES3055030T3 (en) | 2015-05-06 | 2026-02-09 | Uti Lp | Nanoparticle compositions for sustained therapy |
| AU2017225787B2 (en) * | 2016-03-03 | 2021-09-23 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| KR20190044029A (ko) * | 2016-05-18 | 2019-04-29 | 알버트 아인슈타인 컬리지 오브 메디슨, 인크. | 변이체 pd-l1 폴리펩타이드, t-세포 조절 다량체 폴리펩타이드 및 이들의 사용 방법 |
| MX2019005497A (es) * | 2016-11-09 | 2019-11-18 | Uti Lp | Moleculas de pmhc de clase ii recombinantes. |
| EP3678677A4 (en) * | 2017-09-07 | 2021-06-16 | Cue Biopharma, Inc. | Antigen-presenting polypeptides and methods of use thereof |
| EP4211149A4 (en) * | 2020-09-09 | 2024-10-09 | Cue Biopharma, Inc. | MULTIMERIC POLYPEPTIDES MODULATING MHC CLASS II T CELLS FOR THE TREATMENT OF TYPE 1 DIABETES MELLITUS (T1D) AND METHODS OF USE THEREOF |
-
2020
- 2020-02-21 JP JP2021543384A patent/JP7691927B2/ja active Active
- 2020-02-21 WO PCT/US2020/019244 patent/WO2020180501A1/en not_active Ceased
- 2020-02-21 EP EP20767049.8A patent/EP3935079A4/en active Pending
-
2021
- 2021-08-05 US US17/394,960 patent/US20220106378A1/en active Pending
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