JPWO2020178741A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2020178741A5 JPWO2020178741A5 JP2021552602A JP2021552602A JPWO2020178741A5 JP WO2020178741 A5 JPWO2020178741 A5 JP WO2020178741A5 JP 2021552602 A JP2021552602 A JP 2021552602A JP 2021552602 A JP2021552602 A JP 2021552602A JP WO2020178741 A5 JPWO2020178741 A5 JP WO2020178741A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- tcr
- acid sequence
- seq
- constant region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962813645P | 2019-03-04 | 2019-03-04 | |
| US62/813,645 | 2019-03-04 | ||
| PCT/IB2020/051810 WO2020178741A1 (en) | 2019-03-04 | 2020-03-03 | T cell receptors and methods of use thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022523971A JP2022523971A (ja) | 2022-04-27 |
| JPWO2020178741A5 true JPWO2020178741A5 (https=) | 2023-03-13 |
| JP2022523971A5 JP2022523971A5 (https=) | 2023-03-13 |
| JP7727546B2 JP7727546B2 (ja) | 2025-08-21 |
Family
ID=72336931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021552602A Active JP7727546B2 (ja) | 2019-03-04 | 2020-03-03 | Ｔ細胞受容体及びその使用方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US12522644B2 (https=) |
| EP (1) | EP3935176A4 (https=) |
| JP (1) | JP7727546B2 (https=) |
| KR (1) | KR20210149048A (https=) |
| CN (1) | CN113795584B (https=) |
| AU (1) | AU2020231194A1 (https=) |
| BR (1) | BR112021017505A2 (https=) |
| CA (1) | CA3132431A1 (https=) |
| IL (1) | IL286046A (https=) |
| MX (1) | MX2021010541A (https=) |
| SG (1) | SG11202109591QA (https=) |
| TW (1) | TW202043250A (https=) |
| WO (1) | WO2020178741A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7748284B2 (ja) | 2019-03-04 | 2025-10-02 | ユニバーシティー ヘルス ネットワーク | Ｔ細胞受容体及びその使用方法 |
| MX2021010541A (es) | 2019-03-04 | 2021-12-15 | Univ Health Network | Receptores de linfocitos t y metodos de uso de estos. |
| CN113795586B (zh) | 2019-03-25 | 2026-03-27 | 大学健康网络 | T细胞受体及其使用方法 |
| WO2025096983A1 (en) * | 2023-11-02 | 2025-05-08 | Board Of Regents, The University Of Texas System | Peptides and engineered t cell receptors targeting tpx2 antigen and methods of use |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1064022A4 (en) | 1998-03-13 | 2004-09-29 | Epimmune Inc | HLA BINDING PROTEINS AND THEIR USE |
| ATE395930T1 (de) * | 1999-10-22 | 2008-06-15 | Aventis Pasteur | Verfahren zur erregung und/oder verstärkung der immunantwort gegen tumorantigene |
| US6506875B1 (en) | 2000-09-26 | 2003-01-14 | Ludwig Institute For Cancer Research | Isolated peptides which bind to HLA-C molecules and uses thereof |
| CN101175853A (zh) | 2005-03-16 | 2008-05-07 | Dna吉诺特克股份有限公司 | 用于保存来自体液的核酸的组合物和方法 |
| AU2008206442B2 (en) | 2007-01-12 | 2012-10-18 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | gp100-specific T cell receptors and related materials and methods of use |
| JP5292550B2 (ja) | 2007-03-23 | 2013-09-18 | 静岡県 | Ｔ細胞レセプターβ鎖遺伝子及びα鎖遺伝子 |
| CA2682093A1 (en) | 2007-03-29 | 2008-10-09 | Technion Research & Development Foundation Ltd. | Antibodies, methods and kits for diagnosing and treating melanoma |
| US9051391B2 (en) * | 2007-06-11 | 2015-06-09 | Takara Bio Inc. | Method for expression of specific gene |
| WO2010037395A2 (en) * | 2008-10-01 | 2010-04-08 | Dako Denmark A/S | Mhc multimers in cancer vaccines and immune monitoring |
| PT2413956T (pt) | 2009-04-02 | 2016-12-30 | Vaxon Biotech | Identificação, optimização e utilização de epitopos crípticos hla-a24 para imunoterapia |
| WO2011140284A2 (en) | 2010-05-04 | 2011-11-10 | Fred Hutchinson Cancer Research Center | Conditional superagonist ctl ligands for the promotion of tumor-specific ctl responses |
| ES2635335T3 (es) | 2010-09-20 | 2017-10-03 | Biontech Cell & Gene Therapies Gmbh | Receptores de células T específicos de antígeno y epítopos de células T |
| PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| WO2014207708A2 (en) | 2013-06-28 | 2014-12-31 | Auckland Uniservices Limited | Amino acid and peptide conjugates and conjugation process |
| KR101503341B1 (ko) | 2014-03-12 | 2015-03-18 | 국립암센터 | 자가암항원 특이적 cd8+ t 세포의 분리 및 증식방법 |
| EP3155426B1 (en) * | 2014-06-13 | 2023-07-19 | Immudex ApS | General detection and isolation of specific cells by binding of labeled molecules |
| AU2015343013B2 (en) | 2014-11-05 | 2020-07-16 | Board Of Regents, The University Of Texas System | Gene modified immune effector cells and engineered cells for expansion of immune effector cells |
| NL2014935B1 (en) | 2015-06-08 | 2017-02-03 | Applied Immune Tech Ltd | T cell receptor like antibodies having fine specificity. |
| WO2017120428A2 (en) | 2016-01-06 | 2017-07-13 | Health Research, Inc. | Compositions and libraries comprising recombinant t-cell receptors and methods of using recombinant t-cell receptors |
| US11396536B2 (en) | 2016-04-27 | 2022-07-26 | University Health Network | Peptide-HLA complexes and methods of producing same |
| EP3935171A4 (en) | 2019-03-04 | 2022-12-28 | University Health Network | T-CELL RECEPTORS AND METHODS OF USE THEREOF |
| JP7748284B2 (ja) | 2019-03-04 | 2025-10-02 | ユニバーシティー ヘルス ネットワーク | Ｔ細胞受容体及びその使用方法 |
| CN113795585B (zh) | 2019-03-04 | 2026-03-06 | 大学健康网络 | T细胞受体及其使用方法 |
| WO2020178738A1 (en) | 2019-03-04 | 2020-09-10 | University Health Network | T cell receptors and methods of use thereof |
| AU2020231927A1 (en) | 2019-03-04 | 2021-09-30 | University Health Network | T cell receptors and methods of use thereof |
| MX2021010541A (es) | 2019-03-04 | 2021-12-15 | Univ Health Network | Receptores de linfocitos t y metodos de uso de estos. |
| CN113795586B (zh) | 2019-03-25 | 2026-03-27 | 大学健康网络 | T细胞受体及其使用方法 |
-
2020
- 2020-03-03 MX MX2021010541A patent/MX2021010541A/es unknown
- 2020-03-03 US US17/436,934 patent/US12522644B2/en active Active
- 2020-03-03 SG SG11202109591Q patent/SG11202109591QA/en unknown
- 2020-03-03 KR KR1020217031557A patent/KR20210149048A/ko active Pending
- 2020-03-03 AU AU2020231194A patent/AU2020231194A1/en active Pending
- 2020-03-03 BR BR112021017505A patent/BR112021017505A2/pt unknown
- 2020-03-03 CN CN202080025149.9A patent/CN113795584B/zh active Active
- 2020-03-03 WO PCT/IB2020/051810 patent/WO2020178741A1/en not_active Ceased
- 2020-03-03 EP EP20767177.7A patent/EP3935176A4/en active Pending
- 2020-03-03 JP JP2021552602A patent/JP7727546B2/ja active Active
- 2020-03-03 CA CA3132431A patent/CA3132431A1/en active Pending
- 2020-03-04 TW TW109107115A patent/TW202043250A/zh unknown
-
2021
- 2021-09-01 IL IL286046A patent/IL286046A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Li et al. | Increasing the safety and efficacy of chimeric antigen receptor T cell therapy | |
| Spear et al. | Strategies to genetically engineer T cells for cancer immunotherapy | |
| JP2022109953A5 (https=) | ||
| AU2020211375B2 (en) | Receptors providing targeted costimulation for adoptive cell therapy | |
| US11052138B2 (en) | Use of car and bite technology coupled with an SCFV from an antibody against human thymidine kinase 1 to specifically target tumors | |
| CN109694854B (zh) | 通用型嵌合抗原受体t细胞制备技术 | |
| Shilyansky et al. | T-cell receptor usage by melanoma-specific clonal and highly oligoclonal tumor-infiltrating lymphocyte lines. | |
| JP2020509767A5 (https=) | ||
| Essand et al. | Genetically engineered T cells for the treatment of cancer | |
| CN112088008A (zh) | 修饰细胞的扩增及其用途 | |
| Tsang et al. | Phenotypic stability of a cytotoxic T-cell line directed against an immunodominant epitope of human carcinoembryonic antigen. | |
| JP2023534808A (ja) | 養子細胞療法のための標的共刺激を提供する受容体 | |
| WO2016100232A1 (en) | Bispecific or-gate chimeric antigen receptor responsive to cd19 and cd20 | |
| JPWO2019173324A5 (https=) | ||
| CN114616337A (zh) | 嵌合CD3融合蛋白与基于anti-CD3的双特异性T细胞激活元件的联合表达 | |
| WO2017070649A1 (en) | Combination methods for immunotherapy | |
| CN108138148A (zh) | T细胞的激活和扩增 | |
| JP2020533962A5 (https=) | ||
| Daniyan et al. | At the Bench: Chimeric antigen receptor (CAR) T cell therapy for the treatment of B cell malignancies | |
| JPWO2020194195A5 (https=) | ||
| JPWO2020178739A5 (https=) | ||
| JPWO2020178742A5 (https=) | ||
| JPWO2020178738A5 (https=) | ||
| JPWO2020178741A5 (https=) | ||
| JPWO2020178740A5 (https=) |