JPWO2020167476A5 - - Google Patents
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- Publication number
- JPWO2020167476A5 JPWO2020167476A5 JP2021546842A JP2021546842A JPWO2020167476A5 JP WO2020167476 A5 JPWO2020167476 A5 JP WO2020167476A5 JP 2021546842 A JP2021546842 A JP 2021546842A JP 2021546842 A JP2021546842 A JP 2021546842A JP WO2020167476 A5 JPWO2020167476 A5 JP WO2020167476A5
- Authority
- JP
- Japan
- Prior art keywords
- phenol
- formulation
- cyclodextrin
- injection
- phenolic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims 18
- 239000000203 mixture Substances 0.000 claims 17
- 238000009472 formulation Methods 0.000 claims 14
- 229920000858 Cyclodextrin Polymers 0.000 claims 7
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 claims 7
- 238000002347 injection Methods 0.000 claims 5
- 239000007924 injection Substances 0.000 claims 5
- ODLHGICHYURWBS-LKONHMLTSA-N trappsol cyclo Chemical compound CC(O)COC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)COCC(O)C)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1COCC(C)O ODLHGICHYURWBS-LKONHMLTSA-N 0.000 claims 5
- 239000002904 solvent Substances 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 230000000699 topical effect Effects 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 1
- 210000005036 nerve Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962806188P | 2019-02-15 | 2019-02-15 | |
| US62/806,188 | 2019-02-15 | ||
| PCT/US2020/015690 WO2020167476A1 (en) | 2019-02-15 | 2020-01-29 | Injectable phenol formulations and methods of their use |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022520779A JP2022520779A (ja) | 2022-04-01 |
| JP2022520779A5 JP2022520779A5 (https=) | 2022-11-08 |
| JPWO2020167476A5 true JPWO2020167476A5 (https=) | 2022-11-08 |
| JP7455852B2 JP7455852B2 (ja) | 2024-03-26 |
Family
ID=72042651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021546842A Active JP7455852B2 (ja) | 2019-02-15 | 2020-01-29 | 注射可能なフェノール製剤およびその使用の方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US10959962B2 (https=) |
| EP (1) | EP3923916A4 (https=) |
| JP (1) | JP7455852B2 (https=) |
| CA (1) | CA3129648A1 (https=) |
| MX (1) | MX2021009777A (https=) |
| WO (1) | WO2020167476A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112691091A (zh) * | 2021-01-09 | 2021-04-23 | 胡宝贤 | 低浓度石炭酸的新应用 |
| US20230190660A1 (en) * | 2021-12-03 | 2023-06-22 | Path | Encapsulated pharmaceutical compositions, related methods of making, and related methods of treatment |
| WO2025235121A1 (en) * | 2024-05-07 | 2025-11-13 | Teclison, Inc. | Tirapazamine compositions and methods |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59152320A (ja) * | 1983-02-17 | 1984-08-31 | Takeda Chem Ind Ltd | 水性製剤 |
| JPH0625056B2 (ja) | 1989-06-01 | 1994-04-06 | 大幸薬品株式会社 | 鎮痙剤 |
| WO2002089849A1 (en) * | 2001-05-07 | 2002-11-14 | Corium International | Compositions and delivery systems for administration of a local anesthetic agent |
| JP4150772B2 (ja) * | 2001-09-14 | 2008-09-17 | 独立行政法人産業技術総合研究所 | シクロデキストリンを含有するフェノール重合物 |
| JP2005538983A (ja) | 2002-07-19 | 2005-12-22 | メステックス アクチエンゲゼルシャフト | 関節痛の治療のための薬剤を製造するための神経毒性物質の使用および同薬剤を適用する方法 |
| LT1713504T (lt) * | 2004-01-30 | 2017-09-11 | Zoetis Services Llc | Antimikrobinis konservantas, skirtas multi-dozinėms kompozicijoms, panaudojant beta-ciklodekstrinus, skirtas skystoms vaisto formoms |
| US20120190750A1 (en) * | 2011-01-24 | 2012-07-26 | Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. | Stable ready to use injectable paracetamol formulation |
| ES2784629T3 (es) * | 2011-11-29 | 2020-09-29 | Jurox Pty Ltd | Composiciones farmacéuticas inyectables estables que comprenden 2-hidroxipropil-beta-ciclodextrina y alfaxalona |
| US9295512B2 (en) | 2013-03-15 | 2016-03-29 | Myoscience, Inc. | Methods and devices for pain management |
| JP6238190B2 (ja) * | 2013-07-04 | 2017-11-29 | 公立大学法人大阪市立大学 | コラーゲン産生促進用、エラスチン産生促進用および／またはケラチノサイト遊走促進用組成物 |
| EP3024472A4 (en) | 2013-07-22 | 2017-06-28 | Kineta One, LLC | Ophthalmic uses of toxin-based therapeutic peptides and pharmaceutical compositions thereof |
| CN103602325B (zh) * | 2013-11-18 | 2016-08-03 | 中国石油化工股份有限公司 | 一种延缓交联凝胶调剖剂及其制备方法 |
| US20170209389A1 (en) | 2014-07-23 | 2017-07-27 | Landy Toth | Precision chemical ablation and treatment of tissues |
| EP4059522A1 (en) * | 2015-02-06 | 2022-09-21 | Marinus Pharmaceuticals, Inc. | Intravenous ganaxolone formulations and their use in treating status epilepticus and other seizure disorders |
| US9855317B2 (en) | 2015-04-27 | 2018-01-02 | Reflex Medical, Inc. | Systems and methods for sympathetic cardiopulmonary neuromodulation |
| WO2017180708A1 (en) * | 2016-04-12 | 2017-10-19 | Cell and Molecular Tissue Engineering, LLC | Systems, methods and products for minimizing tissue reactions and tissue injury at an infusion site |
-
2020
- 2020-01-29 CA CA3129648A patent/CA3129648A1/en active Pending
- 2020-01-29 WO PCT/US2020/015690 patent/WO2020167476A1/en not_active Ceased
- 2020-01-29 MX MX2021009777A patent/MX2021009777A/es unknown
- 2020-01-29 EP EP20756108.5A patent/EP3923916A4/en active Pending
- 2020-01-29 JP JP2021546842A patent/JP7455852B2/ja active Active
- 2020-01-29 US US16/776,184 patent/US10959962B2/en active Active
-
2021
- 2021-01-28 US US17/160,993 patent/US11083695B2/en active Active
- 2021-01-28 US US17/160,951 patent/US11083694B2/en active Active
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