JPWO2020163248A5 - - Google Patents
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- JPWO2020163248A5 JPWO2020163248A5 JP2021545714A JP2021545714A JPWO2020163248A5 JP WO2020163248 A5 JPWO2020163248 A5 JP WO2020163248A5 JP 2021545714 A JP2021545714 A JP 2021545714A JP 2021545714 A JP2021545714 A JP 2021545714A JP WO2020163248 A5 JPWO2020163248 A5 JP WO2020163248A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- pharmaceutically acceptable
- alkyl
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962800779P | 2019-02-04 | 2019-02-04 | |
| US201962800691P | 2019-02-04 | 2019-02-04 | |
| US201962800720P | 2019-02-04 | 2019-02-04 | |
| US62/800,720 | 2019-02-04 | ||
| US62/800,691 | 2019-02-04 | ||
| US62/800,779 | 2019-02-04 | ||
| US201962801206P | 2019-02-05 | 2019-02-05 | |
| US201962801236P | 2019-02-05 | 2019-02-05 | |
| US201962801208P | 2019-02-05 | 2019-02-05 | |
| US201962801212P | 2019-02-05 | 2019-02-05 | |
| US201962801231P | 2019-02-05 | 2019-02-05 | |
| US201962801387P | 2019-02-05 | 2019-02-05 | |
| US62/801,208 | 2019-02-05 | ||
| US62/801,231 | 2019-02-05 | ||
| US62/801,387 | 2019-02-05 | ||
| US62/801,206 | 2019-02-05 | ||
| US62/801,236 | 2019-02-05 | ||
| US62/801,212 | 2019-02-05 | ||
| PCT/US2020/016460 WO2020163248A1 (en) | 2019-02-04 | 2020-02-03 | Methods and compositions for modulating splicing |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022519636A JP2022519636A (ja) | 2022-03-24 |
| JP2022519636A5 JP2022519636A5 (https=) | 2023-02-09 |
| JPWO2020163248A5 true JPWO2020163248A5 (https=) | 2023-02-09 |
| JP7682096B2 JP7682096B2 (ja) | 2025-05-23 |
Family
ID=71948378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021545714A Active JP7682096B2 (ja) | 2019-02-04 | 2020-02-03 | スプライシングを調節するための方法および組成物 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP3920917A4 (https=) |
| JP (1) | JP7682096B2 (https=) |
| KR (1) | KR102925387B1 (https=) |
| CN (2) | CN114007614A (https=) |
| WO (1) | WO2020163248A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI721623B (zh) | 2018-10-31 | 2021-03-11 | 美商基利科學股份有限公司 | 經取代之6-氮雜苯并咪唑化合物 |
| TW202136261A (zh) | 2018-10-31 | 2021-10-01 | 美商基利科學股份有限公司 | 經取代之6-氮雜苯并咪唑化合物 |
| WO2020163405A1 (en) | 2019-02-05 | 2020-08-13 | Skyhawk Therapeutics, Inc. | Methods and compositions for modulating splicing |
| JP7551629B2 (ja) | 2019-02-05 | 2024-09-17 | スカイホーク・セラピューティクス・インコーポレーテッド | スプライシングを調節するための方法および組成物 |
| WO2020163401A1 (en) * | 2019-02-05 | 2020-08-13 | Skyhawk Therapeutics, Inc. | Methods and compositions for modulating splicing |
| JP7603594B2 (ja) * | 2019-02-06 | 2024-12-20 | スカイホーク・セラピューティクス・インコーポレーテッド | スプライシングを調節するための方法および組成物 |
| JP7603595B2 (ja) * | 2019-02-06 | 2024-12-20 | スカイホーク・セラピューティクス・インコーポレーテッド | スプライシングを調節するための方法および組成物 |
| US11453681B2 (en) | 2019-05-23 | 2022-09-27 | Gilead Sciences, Inc. | Substituted eneoxindoles and uses thereof |
| TW202131920A (zh) | 2019-11-01 | 2021-09-01 | 瑞士商諾華公司 | 剪接調節子用於減慢杭丁頓氏舞蹈症進展的治療之用途 |
| US11618751B1 (en) | 2022-03-25 | 2023-04-04 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives |
| CA3182912A1 (en) | 2020-05-13 | 2021-11-18 | Chdi Foundation, Inc. | Htt modulators for treating huntington's disease |
| MX2023001558A (es) * | 2020-08-05 | 2023-04-26 | Skyhawk Therapeutics Inc | Composiciones para modular el corte y empalme. |
| IL301964A (en) | 2020-10-08 | 2023-06-01 | Redona Therapeutics Inc | History of benzo[H]quinazoline-4-amine and thiano[2,3-H]quinazoline-4-amine for cancer treatment |
| US11319319B1 (en) | 2021-04-07 | 2022-05-03 | Ventus Therapeutics U.S., Inc. | Compounds for inhibiting NLRP3 and uses thereof |
| US20240239758A1 (en) | 2021-04-28 | 2024-07-18 | Astellas Pharma Inc. | Substituted triazine compound |
| KR20240019083A (ko) * | 2021-06-04 | 2024-02-14 | 에프. 호프만-라 로슈 아게 | 트리아진 유도체 및 암 치료에서 이의 용도 |
| MX2024005933A (es) | 2021-11-17 | 2024-08-06 | Chdi Foundation Inc | Moduladores de htt pata tratar la enfermedad de huntington. |
| US20260015353A1 (en) * | 2022-07-21 | 2026-01-15 | Hoffmann-La Roche Inc. | Novel compounds |
| US12331048B2 (en) | 2022-10-31 | 2025-06-17 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors |
| WO2026067767A1 (zh) * | 2024-09-30 | 2026-04-02 | 普罗思特(南京)生物科技有限公司 | 取代的哒嗪衍生物及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ227684A (en) * | 1988-01-30 | 1991-07-26 | Merck Sharp & Dohme | Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions |
| GB9005737D0 (en) * | 1990-03-14 | 1990-05-09 | Beecham Group Plc | Novel compounds |
| UA92083C2 (ru) * | 2006-05-19 | 2010-09-27 | Эбботт Леборетриз | Азабициклические алкановые производные, замещенные конденсированным бициклогетероциклом |
| JP2020523365A (ja) * | 2017-06-14 | 2020-08-06 | ピーティーシー セラピューティクス，インコーポレーテッド | Ｒｎａスプライシングを改変する方法 |
| EA202092001A1 (ru) * | 2018-03-27 | 2021-01-29 | ПиТиСи ТЕРАПЬЮТИКС, ИНК. | Соединения для лечения болезни гентингтона |
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2020
- 2020-02-03 KR KR1020217028194A patent/KR102925387B1/ko active Active
- 2020-02-03 CN CN202080026934.6A patent/CN114007614A/zh active Pending
- 2020-02-03 JP JP2021545714A patent/JP7682096B2/ja active Active
- 2020-02-03 CN CN202411409049.2A patent/CN119320388A/zh active Pending
- 2020-02-03 EP EP20752500.7A patent/EP3920917A4/en active Pending
- 2020-02-03 WO PCT/US2020/016460 patent/WO2020163248A1/en not_active Ceased