JPWO2020150605A5 - - Google Patents
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- Publication number
- JPWO2020150605A5 JPWO2020150605A5 JP2021541224A JP2021541224A JPWO2020150605A5 JP WO2020150605 A5 JPWO2020150605 A5 JP WO2020150605A5 JP 2021541224 A JP2021541224 A JP 2021541224A JP 2021541224 A JP2021541224 A JP 2021541224A JP WO2020150605 A5 JPWO2020150605 A5 JP WO2020150605A5
- Authority
- JP
- Japan
- Prior art keywords
- melatonin
- carboxylic acid
- powder
- dosage form
- hydrogel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 claims 25
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 claims 25
- 229960003987 melatonin Drugs 0.000 claims 25
- 150000001735 carboxylic acids Chemical class 0.000 claims 20
- 239000000843 powder Substances 0.000 claims 16
- 239000002552 dosage form Substances 0.000 claims 15
- 238000000034 method Methods 0.000 claims 9
- 239000000203 mixture Substances 0.000 claims 9
- 238000007908 dry granulation Methods 0.000 claims 8
- 230000037406 food intake Effects 0.000 claims 8
- 229920000642 polymer Polymers 0.000 claims 8
- 239000002245 particle Substances 0.000 claims 7
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 6
- 239000000017 hydrogel Substances 0.000 claims 6
- 239000008187 granular material Substances 0.000 claims 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- 239000002775 capsule Substances 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 229940124531 pharmaceutical excipient Drugs 0.000 claims 2
- 238000013268 sustained release Methods 0.000 claims 2
- 239000012730 sustained-release form Substances 0.000 claims 2
- 239000003826 tablet Substances 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 208000017164 Chronobiology disease Diseases 0.000 claims 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 claims 1
- 239000007894 caplet Substances 0.000 claims 1
- 230000007812 deficiency Effects 0.000 claims 1
- 206010022437 insomnia Diseases 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000009490 roller compaction Methods 0.000 claims 1
- 208000019116 sleep disease Diseases 0.000 claims 1
- 238000009491 slugging Methods 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 238000009827 uniform distribution Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962794159P | 2019-01-18 | 2019-01-18 | |
| US62/794,159 | 2019-01-18 | ||
| PCT/US2020/014086 WO2020150605A1 (en) | 2019-01-18 | 2020-01-17 | Solid micronized melatonin composition |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022534159A JP2022534159A (ja) | 2022-07-28 |
| JPWO2020150605A5 true JPWO2020150605A5 (https=) | 2023-01-20 |
| JP2022534159A5 JP2022534159A5 (https=) | 2023-01-20 |
Family
ID=71610353
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021541224A Pending JP2022534159A (ja) | 2019-01-18 | 2020-01-17 | 微細化した固形メラトニン組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20200230059A1 (https=) |
| EP (1) | EP3911315A4 (https=) |
| JP (1) | JP2022534159A (https=) |
| CN (1) | CN113490491A (https=) |
| AU (1) | AU2020209940A1 (https=) |
| BR (1) | BR112021013976A2 (https=) |
| CA (1) | CA3126413A1 (https=) |
| MX (1) | MX2021008623A (https=) |
| WO (1) | WO2020150605A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112022012199A2 (pt) * | 2020-01-17 | 2022-09-13 | Nestle Sa | Forma de dosagem com péletes de melatonina de liberação sustentada |
| AU2022242966A1 (en) * | 2021-03-22 | 2023-10-05 | Fertis India Pvt. Ltd. | Agricultural composition comprising melatonin and carboxylic compounds for enhancing antioxidant property to increase crop yield |
| CA3221463A1 (en) * | 2021-06-09 | 2022-12-15 | Agb-Pharma Ab | Melatonin formulation in solid dosage form |
| CA3268494A1 (en) | 2022-10-14 | 2024-04-18 | Société des Produits Nestlé S.A. | DELAYED-RELEASE MELATONIN COMPOSITIONS |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9532952B2 (en) * | 2011-01-28 | 2017-01-03 | Physician's Seal, LLC | Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients |
| US8691275B2 (en) * | 2011-01-28 | 2014-04-08 | Zx Pharma, Llc | Controlled-release melatonin compositions and related methods |
| DK2949322T3 (en) * | 2014-05-28 | 2018-07-23 | Valpharma S P A | FORMULATION FOR ORAL ADMINISTRATION COMPREHENSIVE MELATONIN IN STABLE FORM AND PROCEDURE FOR PREPARING THEREOF |
| ES2684414B1 (es) * | 2017-03-31 | 2019-12-11 | Laboratorios Vinas S A | Composición galénica, para uso oral, que comprende melatonina micronizada y una sal de zinc y método y uso correspondientes |
-
2020
- 2020-01-17 CA CA3126413A patent/CA3126413A1/en active Pending
- 2020-01-17 US US16/746,451 patent/US20200230059A1/en not_active Abandoned
- 2020-01-17 BR BR112021013976-1A patent/BR112021013976A2/pt not_active Application Discontinuation
- 2020-01-17 AU AU2020209940A patent/AU2020209940A1/en not_active Abandoned
- 2020-01-17 WO PCT/US2020/014086 patent/WO2020150605A1/en not_active Ceased
- 2020-01-17 MX MX2021008623A patent/MX2021008623A/es unknown
- 2020-01-17 CN CN202080009397.4A patent/CN113490491A/zh active Pending
- 2020-01-17 US US17/423,705 patent/US20220079921A1/en not_active Abandoned
- 2020-01-17 JP JP2021541224A patent/JP2022534159A/ja active Pending
- 2020-01-17 EP EP20740875.8A patent/EP3911315A4/en active Pending
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