JPWO2020150478A5 - - Google Patents
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- Publication number
- JPWO2020150478A5 JPWO2020150478A5 JP2021541017A JP2021541017A JPWO2020150478A5 JP WO2020150478 A5 JPWO2020150478 A5 JP WO2020150478A5 JP 2021541017 A JP2021541017 A JP 2021541017A JP 2021541017 A JP2021541017 A JP 2021541017A JP WO2020150478 A5 JPWO2020150478 A5 JP WO2020150478A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- hematopoietic stem
- genetically engineered
- grna
- progenitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025202676A JP2026035683A (ja) | 2019-01-16 | 2025-11-25 | 系統特異的抗原の阻害のための組成物および方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962793210P | 2019-01-16 | 2019-01-16 | |
| US62/793,210 | 2019-01-16 | ||
| US201962852573P | 2019-05-24 | 2019-05-24 | |
| US62/852,573 | 2019-05-24 | ||
| PCT/US2020/013887 WO2020150478A1 (en) | 2019-01-16 | 2020-01-16 | Compositions and methods for inhibition of lineage specific antigens |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025202676A Division JP2026035683A (ja) | 2019-01-16 | 2025-11-25 | 系統特異的抗原の阻害のための組成物および方法 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022517618A JP2022517618A (ja) | 2022-03-09 |
| JPWO2020150478A5 true JPWO2020150478A5 (https=) | 2023-01-25 |
| JP2022517618A5 JP2022517618A5 (https=) | 2023-01-25 |
| JP7784707B2 JP7784707B2 (ja) | 2025-12-12 |
Family
ID=71613437
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021541017A Active JP7784707B2 (ja) | 2019-01-16 | 2020-01-16 | 系統特異的抗原の阻害のための組成物および方法 |
| JP2025202676A Pending JP2026035683A (ja) | 2019-01-16 | 2025-11-25 | 系統特異的抗原の阻害のための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025202676A Pending JP2026035683A (ja) | 2019-01-16 | 2025-11-25 | 系統特異的抗原の阻害のための組成物および方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20210260130A1 (https=) |
| EP (1) | EP3911338A4 (https=) |
| JP (2) | JP7784707B2 (https=) |
| KR (1) | KR20210129048A (https=) |
| CN (1) | CN113474452A (https=) |
| AU (1) | AU2020209218A1 (https=) |
| BR (1) | BR112021014010A2 (https=) |
| CA (1) | CA3126677A1 (https=) |
| IL (1) | IL284853A (https=) |
| MX (1) | MX2021008490A (https=) |
| SG (1) | SG11202107639UA (https=) |
| WO (1) | WO2020150478A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201907870VA (en) | 2017-02-28 | 2019-09-27 | Vor Biopharma Inc | Compositions and methods for inhibition of lineage specific proteins |
| CA3110837A1 (en) | 2018-08-28 | 2020-03-05 | Vor Biopharma Inc. | Genetically engineered hematopoietic stem cells and uses thereof |
| CN114423865A (zh) * | 2019-05-23 | 2022-04-29 | Vor生物制药股份有限公司 | Cd33修饰的组合物和方法 |
| US20220290160A1 (en) * | 2019-08-28 | 2022-09-15 | Vor Biopharma Inc. | Compositions and methods for cll1 modification |
| US20240110189A1 (en) * | 2020-08-28 | 2024-04-04 | Vor Biopharma Inc. | Compositions and methods for cll1 modification |
| CA3199623A1 (en) * | 2020-10-27 | 2022-05-05 | Vor Biopharma Inc. | Compositions and methods for treating hematopoietic malignancy |
| CN115443333B (zh) * | 2021-04-27 | 2025-04-25 | 上海驯鹿生物技术有限公司 | 一种基因编辑的造血干细胞及其与car-t细胞的联合应用 |
| US20240384304A1 (en) | 2021-07-06 | 2024-11-21 | Vor Biopharma Inc. | Inhibitor oligonucleotides and methods of use thereof |
| AU2022324093A1 (en) | 2021-08-02 | 2024-02-08 | Vor Biopharma Inc. | Compositions and methods for gene modification |
| WO2024015925A2 (en) | 2022-07-13 | 2024-01-18 | Vor Biopharma Inc. | Compositions and methods for artificial protospacer adjacent motif (pam) generation |
| WO2024073751A1 (en) | 2022-09-29 | 2024-04-04 | Vor Biopharma Inc. | Methods and compositions for gene modification and enrichment |
| WO2025030010A1 (en) | 2023-08-01 | 2025-02-06 | Vor Biopharma Inc. | Compositions comprising genetically engineered hematopoietic stem cells and methods of use thereof |
| BG113932A (bg) * | 2024-07-19 | 2026-01-30 | Медицински университет – Пловдив | Панели и китове от реагенти за измерване на минимална резидуална болест при детска в-клетъчна прекурсорна остра лимфобластна левкемия чрез имунофенотипизация |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3126390B2 (en) * | 2014-04-03 | 2026-01-07 | Cellectis | Cd33 specific chimeric antigen receptors for cancer immunotherapy |
| RU2749113C2 (ru) * | 2015-04-22 | 2021-06-04 | Куревак Аг | Содержащая рнк композиция для лечения опухолевых заболеваний |
| AU2016261358B2 (en) | 2015-05-11 | 2021-09-16 | Editas Medicine, Inc. | Optimized CRISPR/Cas9 systems and methods for gene editing in stem cells |
| CN108290939B (zh) * | 2015-10-16 | 2023-01-13 | 纽约市哥伦比亚大学理事会 | 用于抑制谱系特异性抗原的组合物和方法 |
| BR112018012894A2 (en) | 2015-12-23 | 2018-12-04 | Crispr Therapeutics Ag | Materials and Methods for Treatment of Amyotrophic Lateral Sclerosis and / or Frontotemporal Lobular Degeneration |
| JP2020508056A (ja) | 2017-02-22 | 2020-03-19 | クリスパー・セラピューティクス・アクチェンゲゼルシャフトＣＲＩＳＰＲ Ｔｈｅｒａｐｅｕｔｉｃｓ ＡＧ | 遺伝子編集のための組成物および方法 |
| US11718659B2 (en) * | 2017-08-28 | 2023-08-08 | The Trustees Of Columbia University In The City Of New York | CD33 exon 2 deficient donor stem cells for use with CD33 targeting agents |
-
2020
- 2020-01-16 MX MX2021008490A patent/MX2021008490A/es unknown
- 2020-01-16 WO PCT/US2020/013887 patent/WO2020150478A1/en not_active Ceased
- 2020-01-16 KR KR1020217025362A patent/KR20210129048A/ko active Pending
- 2020-01-16 JP JP2021541017A patent/JP7784707B2/ja active Active
- 2020-01-16 CN CN202080014774.3A patent/CN113474452A/zh active Pending
- 2020-01-16 CA CA3126677A patent/CA3126677A1/en active Pending
- 2020-01-16 SG SG11202107639UA patent/SG11202107639UA/en unknown
- 2020-01-16 BR BR112021014010-7A patent/BR112021014010A2/pt unknown
- 2020-01-16 EP EP20740954.1A patent/EP3911338A4/en active Pending
- 2020-01-16 AU AU2020209218A patent/AU2020209218A1/en active Pending
-
2021
- 2021-04-29 US US17/244,136 patent/US20210260130A1/en active Pending
- 2021-07-14 IL IL284853A patent/IL284853A/en unknown
-
2025
- 2025-11-25 JP JP2025202676A patent/JP2026035683A/ja active Pending
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