JPWO2020142725A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2020142725A5
JPWO2020142725A5 JP2021538996A JP2021538996A JPWO2020142725A5 JP WO2020142725 A5 JPWO2020142725 A5 JP WO2020142725A5 JP 2021538996 A JP2021538996 A JP 2021538996A JP 2021538996 A JP2021538996 A JP 2021538996A JP WO2020142725 A5 JPWO2020142725 A5 JP WO2020142725A5
Authority
JP
Japan
Prior art keywords
mir
item
lnp
virus
copies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021538996A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022516318A (ja
JP2022516318A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/012237 external-priority patent/WO2020142725A1/en
Publication of JP2022516318A publication Critical patent/JP2022516318A/ja
Publication of JPWO2020142725A5 publication Critical patent/JPWO2020142725A5/ja
Publication of JP2022516318A5 publication Critical patent/JP2022516318A5/ja
Priority to JP2024143254A priority Critical patent/JP2024167285A/ja
Pending legal-status Critical Current

Links

JP2021538996A 2019-01-04 2020-01-03 カプセル化ポリヌクレオチド及び使用方法 Pending JP2022516318A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024143254A JP2024167285A (ja) 2019-01-04 2024-08-23 カプセル化ポリヌクレオチド及び使用方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962788504P 2019-01-04 2019-01-04
US62/788,504 2019-01-04
US201962895135P 2019-09-03 2019-09-03
US62/895,135 2019-09-03
PCT/US2020/012237 WO2020142725A1 (en) 2019-01-04 2020-01-03 Encapsulated rna polynucleotides and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024143254A Division JP2024167285A (ja) 2019-01-04 2024-08-23 カプセル化ポリヌクレオチド及び使用方法

Publications (3)

Publication Number Publication Date
JP2022516318A JP2022516318A (ja) 2022-02-25
JPWO2020142725A5 true JPWO2020142725A5 (https=) 2023-01-19
JP2022516318A5 JP2022516318A5 (https=) 2023-01-19

Family

ID=71406664

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021538996A Pending JP2022516318A (ja) 2019-01-04 2020-01-03 カプセル化ポリヌクレオチド及び使用方法
JP2024143254A Pending JP2024167285A (ja) 2019-01-04 2024-08-23 カプセル化ポリヌクレオチド及び使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024143254A Pending JP2024167285A (ja) 2019-01-04 2024-08-23 カプセル化ポリヌクレオチド及び使用方法

Country Status (13)

Country Link
US (1) US20220117902A1 (https=)
EP (1) EP3906039A4 (https=)
JP (2) JP2022516318A (https=)
KR (1) KR20210113260A (https=)
CN (1) CN113453699A (https=)
AU (1) AU2020204989A1 (https=)
BR (1) BR112021013155A2 (https=)
CA (1) CA3124524A1 (https=)
IL (1) IL284433A (https=)
MX (1) MX2021008146A (https=)
SG (1) SG11202107282VA (https=)
TW (1) TW202043480A (https=)
WO (1) WO2020142725A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113166783B (zh) 2018-10-09 2024-10-11 不列颠哥伦比亚大学 包含无有机溶剂和去污剂的转染活性囊泡的组合物和系统以及与之相关的方法
AU2020315800A1 (en) 2019-07-19 2022-03-03 Seneca Therapeutics, Inc. Second generation seneca valley virus oncolytic therapy: compositions and methods thereof
CN114514323A (zh) * 2019-08-05 2022-05-17 复诺健生物科技加拿大有限公司 遗传修饰的肠病毒载体
EP4271389A4 (en) * 2020-12-29 2026-04-08 Rejuvenation Tech Inc COMPOSITIONS AND METHODS FOR ADMINISTRATING RNA
AU2022206676A1 (en) * 2021-01-06 2023-08-24 Elevatebio Technologies, Inc. Encapsulated rna polynucleotides and methods of use
WO2022159508A1 (en) * 2021-01-19 2022-07-28 Seneca Therapeutics, Inc. Armed seneca valley virus oncolytic therapy compositions and methods thereof
EP4297728A1 (en) * 2021-02-23 2024-01-03 Poseida Therapeutics, Inc. Compositions and methods for delivery of nucleic acids
IL307319A (en) * 2021-03-31 2023-11-01 Rejuvenation Tech Inc Compositions and methods for delivery of rna
AU2022328856A1 (en) * 2021-08-17 2024-01-18 Monash University Lipid nanoparticle formulations
CA3234320A1 (en) * 2021-09-30 2023-04-06 Nof Corporation Lipid nanoparticle used for delivering nucleic acid to brain tissue
WO2023054242A1 (ja) * 2021-09-30 2023-04-06 日油株式会社 核酸をリンパ管内皮細胞に送達するために用いられる脂質ナノ粒子
CN113980915B (zh) * 2021-11-04 2023-07-07 江苏省人民医院(南京医科大学第一附属医院) 一种新型的表达cxcl10的复制型溶瘤腺病毒和应用
FR3129833B1 (fr) 2021-12-03 2024-09-06 Univ Claude Bernard Lyon Nanoparticules pour la liberation d’acides nucleiques
WO2023165583A1 (zh) * 2022-03-04 2023-09-07 益杰立科(上海)生物科技有限公司 靶向眼部细胞的递送系统和方法
WO2024009316A1 (en) * 2022-07-04 2024-01-11 Bharat Biotech International Limited Cationic lipid based composition, formulation and use for nucleic acid vaccine delivery and preparation thereof
CN115227674B (zh) * 2022-08-05 2023-07-04 武汉滨会生物科技股份有限公司 包封的溶瘤病毒遗传物质及其应用
WO2024086810A1 (en) * 2022-10-21 2024-04-25 Georgia Tech Research Corporation Lymphatic endothelial cell-specific lipid nanoparticle and uses thereof
EP4704855A1 (en) * 2023-04-26 2026-03-11 Saliogen Therapeutics, Inc. Lipid nanoparticle (lnp) formulations
KR20250042873A (ko) 2023-09-20 2025-03-28 한국과학기술연구원 종양 표적 리간드를 포함하는 지질나노입자, 이의 제조방법 및 이를 포함하는 약학 조성물
WO2025196641A1 (ru) * 2024-03-19 2025-09-25 Биоплатформ Гмбх Гибридные частицы, способ их получения и применение
WO2025230906A1 (en) * 2024-04-29 2025-11-06 Saliogen Therapeutics, Inc. Lipid nanoparticle (lnp) formulations

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7638318B2 (en) * 2003-09-26 2009-12-29 Norvartis Ag Seneca Valley virus based compositions and methods for treating disease
WO2006074526A1 (en) * 2005-01-17 2006-07-20 Viralytics Limited Method and composition for treatment of neoplasms
PL2002003T3 (pl) * 2005-05-27 2016-06-30 Ospedale San Raffaele Srl Wektor genetyczny zawierający mi-RNA
EP2125032A4 (en) * 2007-02-20 2011-02-23 Mayo Foundation CANCER TREATMENT WITH VIRAL NUCLEIC ACID
TW201021853A (en) * 2008-11-17 2010-06-16 Enzon Pharmaceuticals Inc Releasable cationic lipids for nucleic acids delivery systems
JP6093710B2 (ja) * 2011-11-18 2017-03-08 日油株式会社 細胞内動態を改善したカチオン性脂質
US9750819B2 (en) * 2012-05-23 2017-09-05 Ohio State Innovation Foundation Lipid nanoparticle compositions and methods of making and methods of using the same
JP6396891B2 (ja) * 2013-04-17 2018-09-26 新日本製薬株式会社 遺伝子改変コクサッキーウイルス
US20180000953A1 (en) * 2015-01-21 2018-01-04 Moderna Therapeutics, Inc. Lipid nanoparticle compositions
RU2749050C2 (ru) * 2016-01-27 2021-06-03 Онкорус, Инк. Онколитические вирусные векторы и их применение
RU2021127872A (ru) * 2016-06-30 2021-11-09 Онкорус, Инк. Доставка терапевтических полипептидов посредством псевдотипированных онколитических вирусов
WO2018169063A1 (ja) * 2017-03-17 2018-09-20 国立大学法人千葉大学 構造強化されたS-TuDを用いた新規がん治療法
JP6832422B2 (ja) * 2017-04-19 2021-02-24 国立大学法人 東京大学 遺伝子改変コクサッキーウイルス及び医薬組成物
JP7187486B2 (ja) * 2017-05-25 2022-12-12 レイドス, インコーポレイテッド Pd-1およびctla-4二重インヒビターペプチド
AU2018301701A1 (en) * 2017-07-14 2020-02-27 Elevatebio Technologies, Inc. Encapsulated polynucleotides and methods of use

Similar Documents

Publication Publication Date Title
JPWO2020142725A5 (https=)
Wang et al. mRNA-based vaccines and therapeutics: an in-depth survey of current and upcoming clinical applications
Liu et al. mRNA-based cancer therapeutics
Feng et al. RNA therapeutics-research and clinical advancements
Pahle et al. Vectors and strategies for nonviral cancer gene therapy
JP2024167285A (ja) カプセル化ポリヌクレオチド及び使用方法
Kauffman et al. Efficacy and immunogenicity of unmodified and pseudouridine-modified mRNA delivered systemically with lipid nanoparticles in vivo
JP2020530778A5 (https=)
Tyagi et al. Exploiting nanotechnology for the development of microRNA-based cancer therapeutics
JP2021522248A (ja) 粒子状製剤用の凍結保護剤
Anand et al. Metabolic stability and targeted delivery of oligonucleotides: advancing RNA therapeutics beyond the liver
Son et al. Development of mRNA vaccines/therapeutics and their delivery system
Khan et al. Lipid-based colloidal nanoparticles for applications in targeted vaccine delivery
Abaza et al. Lipid nanoparticles: a promising tool for nucleic acid delivery in cancer immunotherapy
JPWO2022150485A5 (https=)
Zwolsman et al. Engineering lipid nanoparticles for mRNA immunotherapy
JP2025527583A (ja) 脂質ナノ粒子の組成物
CN118556131A (zh) 用于蛋白质表达的mRNA及其模板
Begum et al. Advances in targeted gene delivery
Wang et al. Targeted gene delivery systems for T-cell engineering
Arruda et al. Innovative nonviral vectors for small-interfering RNA delivery and therapy
JPWO2021243172A5 (https=)
JPWO2020102285A5 (https=)
RU2021123104A (ru) Инкапсулированные полинуклеотиды рнк и способы их применения
AU2023382622A1 (en) Aerosolized lipid nanoparticles and uses thereof