JPWO2020018291A5 - - Google Patents
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- Publication number
- JPWO2020018291A5 JPWO2020018291A5 JP2021526193A JP2021526193A JPWO2020018291A5 JP WO2020018291 A5 JPWO2020018291 A5 JP WO2020018291A5 JP 2021526193 A JP2021526193 A JP 2021526193A JP 2021526193 A JP2021526193 A JP 2021526193A JP WO2020018291 A5 JPWO2020018291 A5 JP WO2020018291A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- use according
- administered
- tyrosine
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 26
- NHTGHBARYWONDQ-UHFFFAOYSA-N (+-)-α-methyl-tyrosine Chemical compound OC(=O)C(N)(C)CC1=CC=C(O)C=C1 NHTGHBARYWONDQ-UHFFFAOYSA-N 0.000 claims 6
- 239000000556 agonist Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 206010003805 Autism Diseases 0.000 claims 2
- 208000020706 Autistic disease Diseases 0.000 claims 2
- 210000003169 central nervous system Anatomy 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 1
- 239000000808 adrenergic beta-agonist Substances 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229960003692 gamma aminobutyric acid Drugs 0.000 claims 1
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16/040,393 US10751313B2 (en) | 2013-10-22 | 2018-07-19 | Compositions and methods for treating autism |
| US16/040,393 | 2018-07-19 | ||
| PCT/US2019/040569 WO2020018291A1 (en) | 2018-07-19 | 2019-07-03 | Compositions and methods for treating autism |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021530568A JP2021530568A (ja) | 2021-11-11 |
| JP2021530568A5 JP2021530568A5 (https=) | 2022-07-11 |
| JPWO2020018291A5 true JPWO2020018291A5 (https=) | 2022-07-11 |
Family
ID=69164908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021526193A Pending JP2021530568A (ja) | 2018-07-19 | 2019-07-03 | 自閉症を処置するための組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12150924B2 (https=) |
| EP (1) | EP3823626A4 (https=) |
| JP (1) | JP2021530568A (https=) |
| CN (1) | CN112789045A (https=) |
| AU (1) | AU2019306092A1 (https=) |
| WO (1) | WO2020018291A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL319533A (en) * | 2022-09-16 | 2025-05-01 | Francis Peter Halas | A low-dose sustained-release preparation for the relief of symptoms caused by elevated levels of dopamine and norepinephrine |
| US12488022B2 (en) * | 2023-11-27 | 2025-12-02 | Capital One Services, Llc | Systems and methods for identifying data labels for submitting to additional data labeling routines based on embedding clusters |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4189604A (en) | 1975-07-22 | 1980-02-19 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Bestatin |
| CA1108180A (en) | 1976-07-21 | 1981-09-01 | Hamao Umezawa | Analogs of bestatin |
| US4165382A (en) * | 1977-10-17 | 1979-08-21 | Jose Pozuelo | Method of pharmacologically treating schizophrenia with alpha-methyl-para-tyrosine |
| US4117161A (en) | 1977-05-16 | 1978-09-26 | Jose Pozuelo | Method of pharmacologically treating drug addiction with alpha-methyl-para-tyrosine |
| US5206018A (en) | 1978-11-03 | 1993-04-27 | Ayerst, Mckenna & Harrison, Inc. | Use of rapamycin in treatment of tumors |
| US5683981A (en) | 1987-05-22 | 1997-11-04 | Competitive Technologies, Inc. | Cyclic bridged analogs of α-MSH and methods thereof |
| US5674839A (en) | 1987-05-22 | 1997-10-07 | Competitive Technologies, Inc. | Cyclic analogs of alpha-MSH fragments |
| US5073541A (en) | 1987-11-18 | 1991-12-17 | Administrators Of The Tulane Educational Fund | Treatment of small cell lung cancer with somatostatin analogs |
| US5225435A (en) | 1990-05-18 | 1993-07-06 | Yale University | Soluble melanin |
| WO1994022460A1 (en) | 1993-04-05 | 1994-10-13 | University Patents, Inc. | Diagnosis and treatment of erectile dysfunction |
| IT1291633B1 (it) | 1997-04-22 | 1999-01-11 | Pharmaconsult S A S | Uso dell'alfa-metil-p-tirosina per inibire la produzione di melanina nei melanociti dell'iride |
| US20030059471A1 (en) | 1997-12-15 | 2003-03-27 | Compton Bruce Jon | Oral delivery formulation |
| JP4394279B2 (ja) | 1998-03-09 | 2010-01-06 | ジーランド ファーマ アクティーゼルスカブ | 酵素加水分解に対する傾向が減少した薬理学的に活性なペプチド複合体 |
| WO2000010507A2 (en) | 1998-08-21 | 2000-03-02 | The Children's Medical Center Corporation | Use of melanin for inhibition of angiogenesis and macular degeneration |
| AU2001251595A1 (en) | 2000-04-13 | 2001-10-30 | William T Evans | Gaba substrate and the use thereof for treating cognitive and emotional disorders |
| US20030114362A1 (en) | 2001-06-08 | 2003-06-19 | Novaspin Biotech Gmbh | Penta-or tetrapeptide binding to somatostatin receptors and the use of the same |
| MXPA05010945A (es) | 2003-04-09 | 2005-11-25 | Japan Tobacco Inc | Compuesto pentaciclico heteroaromatico y uso medicinal del mismo. |
| CA2582346A1 (en) | 2004-10-01 | 2006-04-13 | The Research Foundation Of State University Of New York | Morphine and morphine precursors |
| EP2455072A1 (en) | 2005-03-11 | 2012-05-23 | Endo Pharmaceuticals Solutions Inc. | Controlled release formulations of octreotide |
| ATE431140T1 (de) | 2005-03-11 | 2009-05-15 | Gpc Biotech Ag | Antiproliferative kombinations-therapie mit satraplatin oder jm118 und docetaxel |
| WO2009054001A1 (en) | 2007-10-22 | 2009-04-30 | Biocon Limited | A pharmaceutical composition and a process thereof |
| CN101965192A (zh) | 2008-03-07 | 2011-02-02 | 法马马有限公司 | 改善的抗肿瘤治疗 |
| US20110098241A1 (en) | 2008-04-14 | 2011-04-28 | Poniard Pharmaceuticals, Inc. | Rapamycin analogs as anti-cancer agents |
| US8003689B2 (en) | 2008-06-20 | 2011-08-23 | Gtx, Inc. | Metabolites of selective androgen receptor modulators and methods of use thereof |
| CA2734828C (en) | 2008-08-20 | 2018-07-24 | J. Silvio Gutkind | Chemoprevention of head and neck squamous cell carcinomas |
| US8110578B2 (en) | 2008-10-27 | 2012-02-07 | Signal Pharmaceuticals, Llc | Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway |
| AU2010233073B2 (en) | 2009-04-10 | 2014-07-31 | Haiyan Qi | Novel anti-aging agents and methods to identify them |
| WO2011112576A1 (en) | 2010-03-10 | 2011-09-15 | Ambrilia Biopharma Inc. | Microspheres for sustained release of octreotide acetate |
| GB201020032D0 (en) | 2010-11-25 | 2011-01-12 | Sigmoid Pharma Ltd | Composition |
| WO2012123819A1 (en) | 2011-03-15 | 2012-09-20 | Optinose As Et Al | Nasal delivery |
| PL220308B1 (pl) | 2011-06-03 | 2015-10-30 | Kobel Buys Krystyna | Zastosowanie klenbuterolu do leczenia objawów autyzmu dziecięcego oraz klenbuterol do zastosowania w leczeniu objawów autyzmu dziecięcego |
| US20130183263A1 (en) | 2012-01-17 | 2013-07-18 | Steven Hoffman | Pharmaceutical compositions and methods |
| US8481498B1 (en) | 2012-01-17 | 2013-07-09 | Steven Hoffman | Pharmaceutical compositions and methods |
| US9763903B2 (en) * | 2013-10-22 | 2017-09-19 | Steven Hoffman | Compositions and methods for treating intestinal hyperpermeability |
| US9326962B2 (en) * | 2013-10-22 | 2016-05-03 | Steven Hoffman | Compositions and methods for treating intestinal hyperpermeability |
| US10751313B2 (en) * | 2013-10-22 | 2020-08-25 | Yamo Pharmaceuticals Llc | Compositions and methods for treating autism |
| US10813901B2 (en) * | 2013-10-22 | 2020-10-27 | Yamo Pharmaceuticals Llc | Compositions and methods for treating autism |
| US20150111878A1 (en) | 2013-10-22 | 2015-04-23 | Steven Hoffman | Compositions and methods for treating intestinal hyperpermeability |
| KR20180015126A (ko) * | 2015-04-14 | 2018-02-12 | 스티븐 호프만 | 자폐증을 치료하기 위한 조성물 및 방법 |
-
2019
- 2019-07-03 WO PCT/US2019/040569 patent/WO2020018291A1/en not_active Ceased
- 2019-07-03 JP JP2021526193A patent/JP2021530568A/ja active Pending
- 2019-07-03 EP EP19838492.7A patent/EP3823626A4/en not_active Withdrawn
- 2019-07-03 AU AU2019306092A patent/AU2019306092A1/en not_active Abandoned
- 2019-07-03 CN CN201980048387.9A patent/CN112789045A/zh active Pending
- 2019-07-03 US US17/261,397 patent/US12150924B2/en active Active
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