JPWO2020010309A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2020010309A5 JPWO2020010309A5 JP2021521945A JP2021521945A JPWO2020010309A5 JP WO2020010309 A5 JPWO2020010309 A5 JP WO2020010309A5 JP 2021521945 A JP2021521945 A JP 2021521945A JP 2021521945 A JP2021521945 A JP 2021521945A JP WO2020010309 A5 JPWO2020010309 A5 JP WO2020010309A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- group
- compound
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 27
- 150000003839 salts Chemical class 0.000 claims 27
- 125000000217 alkyl group Chemical group 0.000 claims 13
- 125000003545 alkoxy group Chemical group 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 7
- 125000005347 halocycloalkyl group Chemical group 0.000 claims 6
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical compound C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 4
- 125000003118 aryl group Chemical group 0.000 claims 3
- 229910052799 carbon Inorganic materials 0.000 claims 3
- 229910052736 halogen Inorganic materials 0.000 claims 3
- 150000002367 halogens Chemical class 0.000 claims 3
- 125000001072 heteroaryl group Chemical group 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 238000000338 in vitro Methods 0.000 claims 3
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims 2
- 235000010290 biphenyl Nutrition 0.000 claims 2
- 239000004305 biphenyl Substances 0.000 claims 2
- 108010062584 glycollate oxidase Proteins 0.000 claims 2
- 125000000623 heterocyclic group Chemical group 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 208000000891 primary hyperoxaluria type 1 Diseases 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- 125000004643 (C1-C12) haloalkoxy group Chemical group 0.000 claims 1
- 125000004641 (C1-C12) haloalkyl group Chemical group 0.000 claims 1
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 claims 1
- 208000000913 Kidney Calculi Diseases 0.000 claims 1
- 206010029148 Nephrolithiasis Diseases 0.000 claims 1
- 125000002252 acyl group Chemical group 0.000 claims 1
- 125000000304 alkynyl group Chemical group 0.000 claims 1
- 125000004474 heteroalkylene group Chemical group 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862694918P | 2018-07-06 | 2018-07-06 | |
| US62/694,918 | 2018-07-06 | ||
| US201962827573P | 2019-04-01 | 2019-04-01 | |
| US62/827,573 | 2019-04-01 | ||
| PCT/US2019/040690 WO2020010309A1 (en) | 2018-07-06 | 2019-07-05 | Triazole glycolate oxidase inhibitors |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021530560A JP2021530560A (ja) | 2021-11-11 |
| JP2021530560A5 JP2021530560A5 (https=) | 2022-07-13 |
| JPWO2020010309A5 true JPWO2020010309A5 (https=) | 2022-07-13 |
| JP7348705B2 JP7348705B2 (ja) | 2023-09-21 |
Family
ID=67441692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021521945A Active JP7348705B2 (ja) | 2018-07-06 | 2019-07-05 | トリアゾールグリコール酸オキシダーゼ阻害剤 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11401246B2 (https=) |
| EP (1) | EP3817816A1 (https=) |
| JP (1) | JP7348705B2 (https=) |
| KR (1) | KR102865323B1 (https=) |
| CN (1) | CN112399873B (https=) |
| AU (1) | AU2019297523B2 (https=) |
| BR (1) | BR112021000050A2 (https=) |
| CO (1) | CO2021001277A2 (https=) |
| IL (1) | IL279952B2 (https=) |
| MX (1) | MX2021000051A (https=) |
| PE (1) | PE20210859A1 (https=) |
| SA (1) | SA521420951B1 (https=) |
| SG (1) | SG11202012930RA (https=) |
| WO (1) | WO2020010309A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112021000050A2 (pt) | 2018-07-06 | 2021-04-06 | Orfan Biotech Inc. | Inibidores de triazol glicolato oxidase |
| AU2020376792B2 (en) | 2019-11-01 | 2025-10-02 | Lilac Therapeutics, Inc. | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors |
| EP4087836B1 (en) * | 2020-01-08 | 2025-10-08 | Cantero Therapeutics, Inc. | Processes for preparing triazole glycolate oxidase inhibitors |
| WO2022066933A1 (en) * | 2020-09-24 | 2022-03-31 | Chinook Therapeutics Canada, Inc. | Pentafluoro-sulfanyl -substituted triazolyl compounds and methods of use thereof |
| JP2024538054A (ja) * | 2021-10-11 | 2024-10-18 | カンテロ セラピューティクス，インコーポレイティド | 高シュウ酸尿症及び腎結石の治療のための１ｈ－１，２，３－トリアゾール－４－カルボン酸 |
| WO2024109917A1 (zh) * | 2022-11-25 | 2024-05-30 | 西藏海思科制药有限公司 | 一种三唑衍生物及其在医药上的应用 |
| WO2024212137A1 (en) * | 2023-04-12 | 2024-10-17 | Cantero Therapeutics, Inc. | Crystalline forms of a 1h-1, 2, 3-triazole-4-carboxylic acid compound |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0774218B2 (ja) * | 1987-03-02 | 1995-08-09 | 第一製薬株式会社 | ベンゾピラノトリアゾ−ル誘導体 |
| US6187326B1 (en) | 1998-12-29 | 2001-02-13 | Thomas T. Yamashita | Soil amendment composition |
| US7022702B2 (en) | 2000-04-07 | 2006-04-04 | Qlt Inc. | Antiproliferative 1,2,3-thiadiazole compounds |
| CA2546353A1 (en) | 2003-11-19 | 2005-06-09 | Array Biopharma Inc. | Bicyclic inhibitors of mek and methods of use thereof |
| US7829712B2 (en) | 2004-09-20 | 2010-11-09 | Xenon Pharmaceuticals Inc. | Pyridazine derivatives for inhibiting human stearoyl-CoA-desaturase |
| CN101307307A (zh) * | 2008-07-11 | 2008-11-19 | 华东理工大学 | 一种乙醇酸氧化酶制剂、制备方法及应用 |
| WO2013104573A1 (en) | 2012-01-10 | 2013-07-18 | F. Hoffmann-La Roche Ag | Pyridazine amide compounds and their use as syk inhibitors |
| JP5455279B1 (ja) | 2012-10-25 | 2014-03-26 | アサヒグループホールディングス株式会社 | ラテックスの増産方法 |
| WO2014113485A1 (en) | 2013-01-15 | 2014-07-24 | Intermune, Inc. | Lysophosphatidic acid receptor antagonists |
| US9392796B2 (en) | 2013-03-15 | 2016-07-19 | Spogen Biotech Inc. | Plant growth-promoting bacteria and methods of use |
| FR3021843B1 (fr) | 2014-06-06 | 2016-07-08 | Lesaffre & Cie | Methode et composition pour ameliorer la productivite de plantes non legumineuses |
| JP5866035B1 (ja) | 2015-01-08 | 2016-02-17 | アサヒグループホールディングス株式会社 | 有効分げつ促進方法 |
| JP7148241B2 (ja) | 2015-03-19 | 2022-10-05 | 三菱商事ライフサイエンス株式会社 | 植物の生長促進や根伸長促進効果且つ付加価値向上効果を有する酵母抽出物 |
| EP3386949A4 (en) * | 2015-12-07 | 2019-11-20 | Wake Forest University Health Sciences | GLYCOLATE OXIDASE INHIBITORS AND METHOD FOR USE FOR THE TREATMENT OF NIERSTEIN |
| MX2020006414A (es) | 2017-12-29 | 2020-09-17 | Biomarin Pharm Inc | Inhibidores de glicolato oxidasa para el tratamiento de enfermedades. |
| EP3731840A4 (en) | 2017-12-29 | 2021-09-15 | Orfan Biotech Inc. | NADPH OXIDASE INHIBITORS AND THEIR USE |
| US11389456B2 (en) | 2018-02-23 | 2022-07-19 | Oxalurx, Inc. | Compounds and methods for treating oxalate-related diseases |
| BR112021000050A2 (pt) | 2018-07-06 | 2021-04-06 | Orfan Biotech Inc. | Inibidores de triazol glicolato oxidase |
| CA3143334A1 (en) | 2019-06-19 | 2020-12-24 | Biomarin Pharmaceutical Inc. | Glycolate oxidase inhibitors for the treatment of disease |
-
2019
- 2019-07-05 BR BR112021000050-0A patent/BR112021000050A2/pt unknown
- 2019-07-05 SG SG11202012930RA patent/SG11202012930RA/en unknown
- 2019-07-05 EP EP19745452.3A patent/EP3817816A1/en active Pending
- 2019-07-05 US US17/255,600 patent/US11401246B2/en active Active
- 2019-07-05 IL IL279952A patent/IL279952B2/en unknown
- 2019-07-05 PE PE2021000011A patent/PE20210859A1/es unknown
- 2019-07-05 CN CN201980045610.4A patent/CN112399873B/zh active Active
- 2019-07-05 AU AU2019297523A patent/AU2019297523B2/en active Active
- 2019-07-05 WO PCT/US2019/040690 patent/WO2020010309A1/en not_active Ceased
- 2019-07-05 JP JP2021521945A patent/JP7348705B2/ja active Active
- 2019-07-05 MX MX2021000051A patent/MX2021000051A/es unknown
- 2019-07-05 KR KR1020217003486A patent/KR102865323B1/ko active Active
-
2021
- 2021-01-03 SA SA521420951A patent/SA521420951B1/ar unknown
- 2021-02-05 CO CONC2021/0001277A patent/CO2021001277A2/es unknown
-
2022
- 2022-06-17 US US17/843,455 patent/US20230143491A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021530560A5 (https=) | ||
| DE69122084T2 (de) | 2-arylthiazolderivat sowie dieses enthaltendes arzneimittel | |
| JP3906935B2 (ja) | Ｎ−置換ジオキソチアゾリジルベンズアミド誘導体及びその製造法 | |
| JP2007504284A5 (https=) | ||
| JP2007502295A5 (https=) | ||
| RU2005128190A (ru) | Ингибиторы фактора подавления миграции макрофагов (фпм) и способы их идентификации | |
| JP2021105002A5 (https=) | ||
| JP2021523200A5 (https=) | ||
| JP2022000482A5 (https=) | ||
| JP2018135343A5 (https=) | ||
| HU211138A9 (en) | Therapeutic amides | |
| JP2008526996A5 (https=) | ||
| JP2010501584A5 (https=) | ||
| RU2015120478A (ru) | Пери-карбинолы | |
| JP2005504789A5 (https=) | ||
| RU2008145971A (ru) | Производные 2-тиоксантина, действующие в качестве ингибиторов мро | |
| JP2017506666A5 (https=) | ||
| JP2006507355A5 (https=) | ||
| JP2019510082A5 (https=) | ||
| JP2022137237A5 (https=) | ||
| JPWO2020010309A5 (https=) | ||
| KR20080034436A (ko) | 암 치료에 사용되는 티아졸 유도체 및 유사체 | |
| JP2007500222A5 (https=) | ||
| KR100608416B1 (ko) | 2-(ｎ-시아노이미노)티아졸리딘-4-온 유도체 | |
| JPWO2023088233A5 (https=) |