JPWO2019183381A5 - - Google Patents
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- Publication number
- JPWO2019183381A5 JPWO2019183381A5 JP2020551278A JP2020551278A JPWO2019183381A5 JP WO2019183381 A5 JPWO2019183381 A5 JP WO2019183381A5 JP 2020551278 A JP2020551278 A JP 2020551278A JP 2020551278 A JP2020551278 A JP 2020551278A JP WO2019183381 A5 JPWO2019183381 A5 JP WO2019183381A5
- Authority
- JP
- Japan
- Prior art keywords
- coe
- alkyl
- independently
- group
- isotope
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 125000000217 alkyl group Chemical group 0.000 claims 10
- 150000001875 compounds Chemical class 0.000 claims 5
- 125000000623 heterocyclic group Chemical group 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- 239000012453 solvate Substances 0.000 claims 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 4
- 125000002950 monocyclic group Chemical group 0.000 claims 4
- 229910052757 nitrogen Inorganic materials 0.000 claims 4
- 206010041925 Staphylococcal infections Diseases 0.000 claims 3
- 125000004103 aminoalkyl group Chemical group 0.000 claims 3
- 125000003118 aryl group Chemical group 0.000 claims 3
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims 3
- 208000015688 methicillin-resistant staphylococcus aureus infectious disease Diseases 0.000 claims 3
- 238000006467 substitution reaction Methods 0.000 claims 3
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 2
- 208000035143 Bacterial infection Diseases 0.000 claims 2
- 241000588697 Enterobacter cloacae Species 0.000 claims 2
- 241000194031 Enterococcus faecium Species 0.000 claims 2
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 claims 2
- 241000191967 Staphylococcus aureus Species 0.000 claims 2
- 241000191963 Staphylococcus epidermidis Species 0.000 claims 2
- 125000003342 alkenyl group Chemical group 0.000 claims 2
- 125000000304 alkynyl group Chemical group 0.000 claims 2
- 208000022362 bacterial infectious disease Diseases 0.000 claims 2
- 229960003085 meticillin Drugs 0.000 claims 2
- 150000002891 organic anions Chemical class 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 241000588724 Escherichia coli Species 0.000 claims 1
- 241000588747 Klebsiella pneumoniae Species 0.000 claims 1
- 241000588652 Neisseria gonorrhoeae Species 0.000 claims 1
- 241000589516 Pseudomonas Species 0.000 claims 1
- 241000607142 Salmonella Species 0.000 claims 1
- 241000607762 Shigella flexneri Species 0.000 claims 1
- 241000607477 Yersinia pseudotuberculosis Species 0.000 claims 1
- 208000025087 Yersinia pseudotuberculosis infectious disease Diseases 0.000 claims 1
- 239000005667 attractant Substances 0.000 claims 1
- 125000002619 bicyclic group Chemical group 0.000 claims 1
- 230000031902 chemoattractant activity Effects 0.000 claims 1
- 125000004122 cyclic group Chemical group 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- JUJWROOIHBZHMG-UHFFFAOYSA-O pyridinium Chemical group C1=CC=[NH+]C=C1 JUJWROOIHBZHMG-UHFFFAOYSA-O 0.000 claims 1
- 125000004076 pyridyl group Chemical group 0.000 claims 1
- 125000001453 quaternary ammonium group Chemical group 0.000 claims 1
- 230000035945 sensitivity Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862647181P | 2018-03-23 | 2018-03-23 | |
| US62/647,181 | 2018-03-23 | ||
| PCT/US2019/023411 WO2019183381A2 (en) | 2018-03-23 | 2019-03-21 | Short conjugated oligoelectrolytes and uses thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021519265A JP2021519265A (ja) | 2021-08-10 |
| JP2021519265A5 JP2021519265A5 (https=) | 2022-03-28 |
| JPWO2019183381A5 true JPWO2019183381A5 (https=) | 2022-03-28 |
| JP7362131B2 JP7362131B2 (ja) | 2023-10-17 |
Family
ID=67986375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020551278A Active JP7362131B2 (ja) | 2018-03-23 | 2019-03-21 | 短い共役オリゴ電解質及びその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11713318B2 (https=) |
| EP (1) | EP3768849A4 (https=) |
| JP (1) | JP7362131B2 (https=) |
| CN (1) | CN112154212A (https=) |
| SG (1) | SG11202009242RA (https=) |
| WO (1) | WO2019183381A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230019027A1 (en) * | 2019-11-15 | 2023-01-19 | The Regents Of The University Of California | Short conjugated oligoelectrolytesand antibiotics |
| CN118119592A (zh) * | 2021-08-16 | 2024-05-31 | 新加坡国立大学 | 用于细胞标记的供体-受体共轭寡聚电解质及其方法 |
| WO2024148293A1 (en) * | 2023-01-05 | 2024-07-11 | William Marsh Rice University | Charged pi-conjugated molecules for the treatment of microbial infections |
| WO2024228880A1 (en) * | 2023-04-26 | 2024-11-07 | The Regents Of The University Of California | Antimicrobial conjugated oligoelectrolytes as broad-spectrum antibiotics |
| CN118021996B (zh) * | 2024-01-16 | 2024-07-30 | 华南理工大学 | 一种抗菌包合材料及其制备方法和应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB726260A (en) | 1952-05-07 | 1955-03-16 | Henri Morren | Quaternary amino compounds and processes for the production thereof |
| ZA802160B (en) * | 1979-04-11 | 1981-04-29 | Ciba Geigy Ag | Distyrylbiphenyls |
| ZA802159B (en) * | 1979-04-11 | 1981-04-29 | Ciba Geigy Ag | Distyrylbenzenes |
| US4482680A (en) * | 1981-09-15 | 1984-11-13 | Dynapol | Quaternary ammonium group-containing polymers having antimicrobial activity |
| US7094929B2 (en) | 2003-03-14 | 2006-08-22 | The Regents Of The University Of California | Water-soluble distyrylbenzene chromophores for applications in optoelectronic technologies |
| WO2005056499A2 (en) | 2003-12-04 | 2005-06-23 | Northwestern University | Oligo(p-phenylene vinylene) amphiphiles and methods for self-assembly |
| CN101035508A (zh) * | 2004-08-09 | 2007-09-12 | 西巴特殊化学制品控股公司 | 荧光增白剂作为抗微生物剂的应用 |
| WO2013020096A2 (en) | 2011-08-03 | 2013-02-07 | Stc.Unm | Antimicrobial materials and methods |
| CN104224775B (zh) | 2014-08-29 | 2017-03-15 | 国家纳米科学中心 | 一种包含四苯乙烯衍生物的药物组合物 |
-
2019
- 2019-03-21 US US17/040,320 patent/US11713318B2/en active Active
- 2019-03-21 SG SG11202009242RA patent/SG11202009242RA/en unknown
- 2019-03-21 CN CN201980031110.5A patent/CN112154212A/zh active Pending
- 2019-03-21 EP EP19772107.9A patent/EP3768849A4/en active Pending
- 2019-03-21 WO PCT/US2019/023411 patent/WO2019183381A2/en not_active Ceased
- 2019-03-21 JP JP2020551278A patent/JP7362131B2/ja active Active
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