JPWO2019175109A5 - - Google Patents
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- Publication number
- JPWO2019175109A5 JPWO2019175109A5 JP2020548713A JP2020548713A JPWO2019175109A5 JP WO2019175109 A5 JPWO2019175109 A5 JP WO2019175109A5 JP 2020548713 A JP2020548713 A JP 2020548713A JP 2020548713 A JP2020548713 A JP 2020548713A JP WO2019175109 A5 JPWO2019175109 A5 JP WO2019175109A5
- Authority
- JP
- Japan
- Prior art keywords
- treatment system
- transdermal treatment
- activator
- transdermal
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012190 activator Substances 0.000 claims 21
- 229920001296 polysiloxane Polymers 0.000 claims 19
- 229920000642 polymer Polymers 0.000 claims 17
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 13
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims 10
- 210000003491 Skin Anatomy 0.000 claims 8
- 239000003795 chemical substances by application Substances 0.000 claims 8
- -1 aliphatic acrylates Chemical class 0.000 claims 7
- 239000008199 coating composition Substances 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 7
- NIXOWILDQLNWCW-UHFFFAOYSA-M acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 6
- 239000000853 adhesive Substances 0.000 claims 4
- 229920001577 copolymer Polymers 0.000 claims 4
- CERQOIWHTDAKMF-UHFFFAOYSA-M methacrylate group Chemical group C(C(=C)C)(=O)[O-] CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims 4
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 4
- 229910052710 silicon Inorganic materials 0.000 claims 4
- 239000010703 silicon Substances 0.000 claims 4
- 230000001225 therapeutic Effects 0.000 claims 4
- XEKOWRVHYACXOJ-UHFFFAOYSA-N acetic acid ethyl ester Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims 3
- 239000007795 chemical reaction product Substances 0.000 claims 3
- 239000000178 monomer Substances 0.000 claims 3
- 206010001897 Alzheimer's disease Diseases 0.000 claims 2
- 206010012289 Dementia Diseases 0.000 claims 2
- 206010061536 Parkinson's disease Diseases 0.000 claims 2
- 230000001070 adhesive Effects 0.000 claims 2
- 239000011248 coating agent Substances 0.000 claims 2
- 238000000576 coating method Methods 0.000 claims 2
- 238000001035 drying Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000008385 outer phase Substances 0.000 claims 2
- 239000012071 phase Substances 0.000 claims 2
- 229920000058 polyacrylate Polymers 0.000 claims 2
- 229920002050 silicone resin Polymers 0.000 claims 2
- 206010070976 Craniocerebral injury Diseases 0.000 claims 1
- XSVMFMHYUFZWBK-NSHDSACASA-N EXELON Chemical compound CCN(C)C(=O)OC1=CC=CC([C@H](C)N(C)C)=C1 XSVMFMHYUFZWBK-NSHDSACASA-N 0.000 claims 1
- 239000005977 Ethylene Substances 0.000 claims 1
- 229940117841 Methacrylic Acid Copolymer Drugs 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 229920002367 Polyisobutene Polymers 0.000 claims 1
- 208000005765 Traumatic Brain Injury Diseases 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 229920003144 amino alkyl methacrylate copolymer Polymers 0.000 claims 1
- 229920003147 ammonioalkyl methacrylate copolymer Polymers 0.000 claims 1
- RMRJXGBAOAMLHD-CTAPUXPBSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-CTAPUXPBSA-N 0.000 claims 1
- 229960001736 buprenorphine Drugs 0.000 claims 1
- 125000004432 carbon atoms Chemical group C* 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000006482 condensation reaction Methods 0.000 claims 1
- 238000009792 diffusion process Methods 0.000 claims 1
- 239000008393 encapsulating agent Substances 0.000 claims 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims 1
- 239000003999 initiator Substances 0.000 claims 1
- 238000010030 laminating Methods 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 229920003145 methacrylic acid copolymer Polymers 0.000 claims 1
- DNPFOADIPJWGQH-UHFFFAOYSA-N octan-3-yl prop-2-enoate Chemical compound CCCCCC(CC)OC(=O)C=C DNPFOADIPJWGQH-UHFFFAOYSA-N 0.000 claims 1
- 239000008363 phosphate buffer Substances 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 229920000346 polystyrene-polyisoprene block-polystyrene Polymers 0.000 claims 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 238000004080 punching Methods 0.000 claims 1
- 229920005989 resin Polymers 0.000 claims 1
- 239000011347 resin Substances 0.000 claims 1
- 229960004136 rivastigmine Drugs 0.000 claims 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18161437 | 2018-03-13 | ||
| EP18161437.1 | 2018-03-13 | ||
| PCT/EP2019/056028 WO2019175109A1 (fr) | 2018-03-13 | 2019-03-11 | Système thérapeutique transdermique comprenant un polymère hybride acrylique-silicone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021517572A JP2021517572A (ja) | 2021-07-26 |
| JPWO2019175109A5 true JPWO2019175109A5 (fr) | 2022-03-22 |
Family
ID=61628189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020548713A Abandoned JP2021517572A (ja) | 2018-03-13 | 2019-03-11 | シリコーンアクリルハイブリッドポリマーを含む経皮治療システム |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20210038532A1 (fr) |
| EP (1) | EP3764998A1 (fr) |
| JP (1) | JP2021517572A (fr) |
| CN (1) | CN111971032A (fr) |
| BR (1) | BR112020018300A2 (fr) |
| CA (1) | CA3092757A1 (fr) |
| WO (1) | WO2019175109A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023144276A1 (fr) * | 2022-01-27 | 2023-08-03 | Lts Lohmann Therapie-Systeme Ag | Système thérapeutique transdermique pour l'administration transdermique de sélexipag |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5362496A (en) * | 1993-08-04 | 1994-11-08 | Pharmetrix Corporation | Method and therapeutic system for smoking cessation |
| US5968547A (en) * | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| US6974588B1 (en) * | 1999-12-07 | 2005-12-13 | Elan Pharma International Limited | Transdermal patch for delivering volatile liquid drugs |
| TWI389709B (zh) * | 2005-12-01 | 2013-03-21 | Novartis Ag | 經皮治療系統 |
| DK2024406T3 (da) | 2006-06-06 | 2012-11-05 | Dow Corning | Siliconacrylat-hybridpræparat |
| DE102006054731B4 (de) * | 2006-11-21 | 2013-02-28 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie |
| JP5680061B2 (ja) * | 2009-04-24 | 2015-03-04 | ヘンケル・ユーエス・アイピー・リミテッド・ライアビリティ・カンパニーＨｅｎｋｅｌ ＵＳ ＩＰ ＬＬＣ | シリコーンアクリルハイブリッドポリマーを基剤とする接着剤 |
| SI2468274T1 (sl) * | 2010-12-14 | 2015-10-30 | Acino Ag | Transdermalni terapevtski sistem za dajanje aktivne snovi |
| JP2013139554A (ja) * | 2011-11-29 | 2013-07-18 | Dow Corning Corp | シリコーンアクリレートハイブリッド組成物及び該組成物の製造方法 |
| PL2790685T3 (pl) | 2011-12-12 | 2018-04-30 | Lts Lohmann Therapie-Systeme Ag | System dostarczania przezskórnego zawierający buprenorfinę |
| AU2013205080B2 (en) * | 2012-12-12 | 2016-07-07 | Lts Lohmann Therapie-Systeme Ag | Transdermal Delivery System |
| CN107406554B (zh) * | 2015-02-09 | 2023-04-14 | 美国陶氏有机硅公司 | 多相有机硅丙烯酸类混杂粘弹性组合物及其制备方法 |
| US20170112781A1 (en) * | 2015-10-27 | 2017-04-27 | Noven Pharmaceuticals, Inc. | Transdermal drug delivery systems with polyisobutylene face adhesive |
| WO2018015424A1 (fr) * | 2016-07-22 | 2018-01-25 | Lts Lohmann Therapie-Systeme Ag | Contrôle de domaines adhésifs. |
-
2019
- 2019-03-11 US US15/733,596 patent/US20210038532A1/en not_active Abandoned
- 2019-03-11 CN CN201980025593.8A patent/CN111971032A/zh active Pending
- 2019-03-11 WO PCT/EP2019/056028 patent/WO2019175109A1/fr unknown
- 2019-03-11 CA CA3092757A patent/CA3092757A1/fr active Pending
- 2019-03-11 BR BR112020018300-8A patent/BR112020018300A2/pt not_active Application Discontinuation
- 2019-03-11 EP EP19709060.8A patent/EP3764998A1/fr not_active Withdrawn
- 2019-03-11 JP JP2020548713A patent/JP2021517572A/ja not_active Abandoned
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