JPWO2019170858A5 - - Google Patents
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- Publication number
- JPWO2019170858A5 JPWO2019170858A5 JP2020570643A JP2020570643A JPWO2019170858A5 JP WO2019170858 A5 JPWO2019170858 A5 JP WO2019170858A5 JP 2020570643 A JP2020570643 A JP 2020570643A JP 2020570643 A JP2020570643 A JP 2020570643A JP WO2019170858 A5 JPWO2019170858 A5 JP WO2019170858A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- solid object
- kda
- anionic polymer
- anionic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920006318 anionic polymer Polymers 0.000 claims 66
- 239000007787 solid Substances 0.000 claims 39
- 229920006317 cationic polymer Polymers 0.000 claims 36
- 238000004519 manufacturing process Methods 0.000 claims 20
- 239000010410 layer Substances 0.000 claims 14
- 239000003146 anticoagulant agent Substances 0.000 claims 13
- 229940127219 anticoagulant drug Drugs 0.000 claims 13
- 229920000642 polymer Polymers 0.000 claims 13
- 125000002091 cationic group Chemical group 0.000 claims 11
- 239000011248 coating agent Substances 0.000 claims 11
- 239000011247 coating layer Substances 0.000 claims 11
- 238000000576 coating method Methods 0.000 claims 11
- 150000003839 salts Chemical class 0.000 claims 11
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 10
- 229910052717 sulfur Inorganic materials 0.000 claims 10
- 239000011593 sulfur Substances 0.000 claims 10
- 238000000034 method Methods 0.000 claims 8
- 239000000126 substance Substances 0.000 claims 6
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical group OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims 5
- 229960002897 heparin Drugs 0.000 claims 5
- 229920000669 heparin Polymers 0.000 claims 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 4
- 229960000633 dextran sulfate Drugs 0.000 claims 3
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims 2
- 229920000768 polyamine Polymers 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- 229920002307 Dextran Polymers 0.000 claims 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims 1
- 229960002086 dextran Drugs 0.000 claims 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims 1
- 229910000397 disodium phosphate Inorganic materials 0.000 claims 1
- 235000019800 disodium phosphate Nutrition 0.000 claims 1
- 235000002639 sodium chloride Nutrition 0.000 claims 1
- 229910000162 sodium phosphate Inorganic materials 0.000 claims 1
- 239000001488 sodium phosphate Substances 0.000 claims 1
- 235000011008 sodium phosphates Nutrition 0.000 claims 1
- 229910052938 sodium sulfate Inorganic materials 0.000 claims 1
- 235000011152 sodium sulphate Nutrition 0.000 claims 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18161058.5 | 2018-03-09 | ||
| EP18161058 | 2018-03-09 | ||
| EP18198422 | 2018-10-03 | ||
| EP18198422.0 | 2018-10-13 | ||
| PCT/EP2019/055845 WO2019170858A1 (en) | 2018-03-09 | 2019-03-08 | Improvements to processes for immobilising biological entities |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021514881A JP2021514881A (ja) | 2021-06-17 |
| JPWO2019170858A5 true JPWO2019170858A5 (https=) | 2022-03-16 |
| JP2021514881A5 JP2021514881A5 (https=) | 2022-03-16 |
| JP7365371B2 JP7365371B2 (ja) | 2023-10-19 |
Family
ID=65628797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020570643A Active JP7365371B2 (ja) | 2018-03-09 | 2019-03-08 | 生物学的実体の固定方法の改善 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20190275212A1 (https=) |
| EP (1) | EP3762055B1 (https=) |
| JP (1) | JP7365371B2 (https=) |
| KR (1) | KR102719813B1 (https=) |
| CN (2) | CN111867647B (https=) |
| AU (1) | AU2019232163B2 (https=) |
| CA (1) | CA3093027A1 (https=) |
| ES (1) | ES2953184T3 (https=) |
| SG (1) | SG11202008063YA (https=) |
| WO (1) | WO2019170858A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019232163B2 (en) | 2018-03-09 | 2025-11-20 | Carmeda Ab | Improvements to processes for immobilising biological entities |
| AU2019354085B2 (en) * | 2018-10-03 | 2025-06-05 | Carmeda Ab | Immobilised biological entities |
| JP7573851B2 (ja) * | 2020-07-22 | 2024-10-28 | 国立研究開発法人産業技術総合研究所 | 自己修復多層薄膜およびその製造方法 |
| CN115887792A (zh) * | 2022-11-01 | 2023-04-04 | 上海玮启医疗器械有限公司 | 左心耳封堵器阻流膜及其制备方法、封堵器 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE425372B (sv) | 1977-07-18 | 1982-09-27 | Ird Biomaterial Ab | Sett att heparinisera en elektriskt laddad yta pa en medecinsk artikel avsedd att komma i kontakt med blod och medel for utforande av settet |
| SE8200751L (sv) | 1982-02-09 | 1983-08-10 | Olle Larm | Forfarande for kovalent koppling for framstellning av konjugat och hervid erhallna produkter |
| SE456347B (sv) * | 1982-02-09 | 1988-09-26 | Ird Biomaterial Ab | Ytmodifierat fast substrat samt forfarande for framstellning derav |
| US5049403A (en) | 1989-10-12 | 1991-09-17 | Horsk Hydro A.S. | Process for the preparation of surface modified solid substrates |
| WO1996037241A1 (en) | 1995-05-25 | 1996-11-28 | Minnesota Mining And Manufacturing Company | Process for producing biocompatible surfaces |
| NO984143L (no) | 1998-09-09 | 2000-03-10 | Norsk Hydro As | Ny prosess for å fremstille overflatemodifiserende stoffer |
| US6309660B1 (en) * | 1999-07-28 | 2001-10-30 | Edwards Lifesciences Corp. | Universal biocompatible coating platform for medical devices |
| SE515295C2 (sv) | 1999-11-23 | 2001-07-09 | Medicarb Ab | Förfarande för framställning av konjugat av en biologiskt aktiv polysackarid och ett fast substrat, samt sådana konjugat |
| WO2002085500A1 (en) * | 2001-04-18 | 2002-10-31 | Florida State University Research Foundation, Inc. | Method of preparing free polyelectrolyte membranes |
| CN1193062C (zh) * | 2002-07-10 | 2005-03-16 | 浙江大学 | 用静电吸引层层自组装改性聚酯类材料为表面具有细胞相容性生物材料的方法 |
| CN1257753C (zh) * | 2003-04-28 | 2006-05-31 | 浙江大学 | 采用静电自组装制备抗凝血生物材料的方法 |
| CN1748804A (zh) * | 2005-07-29 | 2006-03-22 | 哈尔滨工业大学 | 人工植入体的抗凝血表面修饰方法 |
| JP2009545333A (ja) | 2006-05-12 | 2009-12-24 | ゴア エンタープライズ ホールディングス，インコーポレイティド | 物理的操作または殺菌の後に大きな生物活性を有する固定化された生物活性物質 |
| US8021677B2 (en) | 2006-05-12 | 2011-09-20 | Gore Enterprise Holdings, Inc. | Immobilized biologically active entities having a high degree of biological activity |
| US20070299511A1 (en) | 2006-06-27 | 2007-12-27 | Gale David C | Thin stent coating |
| LT2126106T (lt) | 2007-02-23 | 2018-01-10 | Sk Chemicals Co., Ltd. | Viii faktoriaus ir jo darinių gavimo ir gryninimo būdas |
| GB0816783D0 (en) * | 2008-09-15 | 2008-10-22 | Carmeda Ab | Immobilised biological entities |
| US8658707B2 (en) | 2009-03-24 | 2014-02-25 | W. L. Gore & Associates, Inc. | Expandable functional TFE copolymer fine powder, the expanded functional products obtained therefrom and reaction of the expanded products |
| GB201004101D0 (en) * | 2010-03-12 | 2010-04-28 | Carmeda Ab | Immobilised biological entities |
| CN101934080B (zh) * | 2010-09-08 | 2012-05-23 | 西北大学 | 一种利用静电自组装涂层改善材料血液相容性的方法 |
| EP2683420B1 (en) * | 2011-03-11 | 2018-05-23 | W. L. Gore & Associates, Inc. | Improvements to immobilised biological entities |
| JP2014532713A (ja) * | 2011-11-02 | 2014-12-08 | ハルシオン，インコーポレイテッド | 創傷処置の方法及び組成物 |
| US9707323B2 (en) | 2012-11-12 | 2017-07-18 | Warsaw Orthopedic, Inc. | Devices and methods for inhibiting adhesion formation |
| US9272075B2 (en) | 2013-02-04 | 2016-03-01 | W.L. Gore & Associates, Inc. | Coating for substrate |
| US20140272232A1 (en) | 2013-03-15 | 2014-09-18 | Bard Access Systems, Inc. | Antithrombic coatings and uses thereof |
| US9566296B2 (en) | 2013-11-08 | 2017-02-14 | Warsaw Orthopedic, Inc. | Multi-layered anti-adhesion device |
| AU2015270839B2 (en) | 2014-06-02 | 2019-08-22 | Tethis, Inc. | Modified biopolymers and methods of producing and using the same |
| SE539575C2 (en) | 2015-07-30 | 2017-10-17 | Tx Medic Ab | Dextran sulfate for use in treating, inhibiting or preventing cardiac fibrosis |
| EP3895614B1 (en) | 2015-12-30 | 2023-01-25 | Dexcom, Inc. | Enzyme immobilized adhesive layer for analyte sensors |
| CN109843343A (zh) | 2016-07-29 | 2019-06-04 | 因贝德生物科学公司 | 用于伤口愈合的方法和组合物 |
| JP6351679B2 (ja) | 2016-09-30 | 2018-07-04 | エスケー ケミカルズ カンパニー リミテッド | 第ｖｉｉｉ因子とその誘導体の製造及び精製方法 |
| CN107753421B (zh) * | 2017-11-07 | 2021-02-09 | 天津大学 | 一种抗生物粘附聚电解质水凝胶及制备方法及应用 |
| AU2019232163B2 (en) | 2018-03-09 | 2025-11-20 | Carmeda Ab | Improvements to processes for immobilising biological entities |
| WO2019170859A2 (en) | 2018-03-09 | 2019-09-12 | Carmeda Ab | Improvements to immobilising biological entities |
-
2019
- 2019-03-08 AU AU2019232163A patent/AU2019232163B2/en active Active
- 2019-03-08 KR KR1020207027247A patent/KR102719813B1/ko active Active
- 2019-03-08 EP EP19708339.7A patent/EP3762055B1/en active Active
- 2019-03-08 ES ES19708339T patent/ES2953184T3/es active Active
- 2019-03-08 WO PCT/EP2019/055845 patent/WO2019170858A1/en not_active Ceased
- 2019-03-08 CA CA3093027A patent/CA3093027A1/en active Pending
- 2019-03-08 JP JP2020570643A patent/JP7365371B2/ja active Active
- 2019-03-08 CN CN201980018210.4A patent/CN111867647B/zh active Active
- 2019-03-08 SG SG11202008063YA patent/SG11202008063YA/en unknown
- 2019-03-08 US US16/297,064 patent/US20190275212A1/en not_active Abandoned
- 2019-03-08 CN CN202310010152.9A patent/CN116173297A/zh active Pending
-
2022
- 2022-07-22 US US17/871,189 patent/US12016978B2/en active Active
-
2024
- 2024-05-13 US US18/662,155 patent/US20240299633A1/en active Pending
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