JPWO2018217809A5 - - Google Patents
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- Publication number
- JPWO2018217809A5 JPWO2018217809A5 JP2019565399A JP2019565399A JPWO2018217809A5 JP WO2018217809 A5 JPWO2018217809 A5 JP WO2018217809A5 JP 2019565399 A JP2019565399 A JP 2019565399A JP 2019565399 A JP2019565399 A JP 2019565399A JP WO2018217809 A5 JPWO2018217809 A5 JP WO2018217809A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- solvate
- pharmaceutically acceptable
- hydrate
- tautomer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762510223P | 2017-05-23 | 2017-05-23 | |
| US62/510,223 | 2017-05-23 | ||
| PCT/US2018/033964 WO2018217809A1 (en) | 2017-05-23 | 2018-05-22 | Pyrazole magl inhibitors |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2020521767A JP2020521767A (ja) | 2020-07-27 |
| JP2020521767A5 JP2020521767A5 (https=) | 2022-07-26 |
| JPWO2018217809A5 true JPWO2018217809A5 (https=) | 2022-07-26 |
| JP7162622B2 JP7162622B2 (ja) | 2022-10-28 |
Family
ID=64397012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019565399A Active JP7162622B2 (ja) | 2017-05-23 | 2018-05-22 | ピラゾールｍａｇｌ阻害剤 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US11149037B2 (https=) |
| EP (1) | EP3634404B1 (https=) |
| JP (1) | JP7162622B2 (https=) |
| KR (1) | KR20200010366A (https=) |
| CN (1) | CN110678177B (https=) |
| AU (1) | AU2018273888A1 (https=) |
| BR (1) | BR112019024488A2 (https=) |
| CA (1) | CA3065898A1 (https=) |
| CL (1) | CL2019003398A1 (https=) |
| CO (1) | CO2019013016A2 (https=) |
| CR (1) | CR20190537A (https=) |
| DO (1) | DOP2019000295A (https=) |
| EA (1) | EA201992504A1 (https=) |
| EC (1) | ECSP19083923A (https=) |
| ES (1) | ES3005265T3 (https=) |
| JO (1) | JOP20190267A1 (https=) |
| MA (1) | MA50405A (https=) |
| MX (1) | MX2019014041A (https=) |
| NI (1) | NI201900120A (https=) |
| PE (1) | PE20200293A1 (https=) |
| PH (1) | PH12019502646A1 (https=) |
| RU (1) | RU2019137094A (https=) |
| WO (1) | WO2018217809A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20141702A1 (es) | 2012-01-06 | 2014-11-19 | Abide Therapeutics Inc | Compuestos de carbamato y preparacion y uso de los mismos |
| WO2017096315A1 (en) | 2015-12-02 | 2017-06-08 | The Scripps Research Institute | TRIAZOLE DAGL(α) INHIBITORS |
| JOP20190107A1 (ar) | 2016-11-16 | 2019-05-09 | Lundbeck La Jolla Research Center Inc | مثبطات أحادي أسيل جليسرول ليباز (magl) |
| JOP20190105A1 (ar) * | 2016-11-16 | 2019-05-09 | Lundbeck La Jolla Research Center Inc | مثبطات أحادي أسيل جليسرول ليباز (magl) |
| US10927105B1 (en) | 2017-05-23 | 2021-02-23 | Lundbeck La Jolla Research Center, Inc. | Pyrazole MAGL inhibitors |
| JOP20190267A1 (ar) | 2017-05-23 | 2019-11-18 | Lundbeck La Jolla Research Center Inc | مثبطات بيرازول magl |
| DK3630744T3 (da) | 2017-05-23 | 2023-03-06 | H Lundbeck As | Pyrazol-magl-inhibitorer |
| WO2019134985A1 (en) | 2018-01-08 | 2019-07-11 | F. Hoffmann-La Roche Ag | Octahydropyrido[1,2-alpha]pyrazines as magl inhibitors |
| BR112021026899A2 (pt) * | 2019-07-09 | 2022-05-10 | Hoffmann La Roche | Compostos heterocíclicos |
| EP4215526A4 (en) * | 2020-09-18 | 2024-10-16 | Shanghai Pharmaceuticals Holding Co., Ltd. | HETEROCYCLIC CARBONYL COMPOUND AND ITS USE |
| CN117177744A (zh) | 2021-01-29 | 2023-12-05 | 塞迪拉治疗股份有限公司 | Cdk2抑制剂及其使用方法 |
| MX2023015436A (es) | 2021-06-26 | 2024-02-21 | Cedilla Therapeutics Inc | Inhibidores de cdk2 y metodos de uso de los mismos. |
| CA3242372A1 (en) | 2021-12-29 | 2023-07-06 | Psy Therapeutics, Inc. | Inhibiting monoacylglycerol lipase (magl) |
| EP4665718A1 (en) | 2023-02-13 | 2025-12-24 | Apogee Pharmaceuticals, Inc. | Small molecules as monoacylglycerol lipase (magl) inhibitors, compositions and use thereof |
| WO2025221154A1 (en) | 2024-04-17 | 2025-10-23 | Captor Therapeutics S.A. | Klhdc2 (kelch domain-containing protein 2) ligase ligands |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3308130A (en) | 1962-04-26 | 1967-03-07 | Du Pont | N-disubstituted carbamyl pyrazoles |
| HK1052509B (en) | 2000-08-14 | 2007-09-07 | Ortho-Mcneil Pharmaceutical, Inc. | Substituted pyrazole |
| US6727364B2 (en) | 2001-04-30 | 2004-04-27 | The Procter & Gamble Company | Triazole compounds useful in treating diseases associated with unwanted cytokine activity |
| CN100379723C (zh) * | 2002-02-19 | 2008-04-09 | 特瓦制药工业有限公司 | 阿托伐他汀半钙脱溶剂的方法和基本上不含有机溶剂的阿托伐他汀半钙 |
| SE0300705D0 (sv) | 2003-03-14 | 2003-03-14 | Biolipox Ab | New compounds |
| US20110172230A1 (en) | 2006-08-23 | 2011-07-14 | Takahiro Ishii | Urea compound or salt thereof |
| JP5657566B2 (ja) | 2008-12-24 | 2015-01-21 | バイアル ポルテラ アンド シーエイ エス エイＢＩＡＬ−Ｐｏｒｔｅｌａ ＆ Ｃａ， Ｓ．Ａ． | 医薬品 |
| CA2830958A1 (en) | 2011-04-06 | 2012-10-11 | The Scripps Research Institute | N1- and n2-carbamoyl-1,2,3-triazole serine hydrolase inhibitors and methods |
| CN103130723B (zh) | 2011-11-30 | 2015-01-14 | 成都地奥制药集团有限公司 | 一种多聚(adp-核糖)聚合酶抑制剂 |
| EP3087067B1 (en) | 2013-12-26 | 2018-10-24 | Takeda Pharmaceutical Company Limited | 4-(piperrazin-1-yl)-pyrrolidin-2-one compounds as monoacylglycerol lipase (magl) inhibitors |
| US10093630B2 (en) | 2014-05-21 | 2018-10-09 | Abide Therapeutics, Inc. | Pyrazole compounds and methods of making and using same |
| US10323513B2 (en) * | 2014-07-23 | 2019-06-18 | Baker Hughes, A Ge Company, Llc | System and method for downhole organic scale monitoring and intervention in a production well |
| US10570146B2 (en) | 2014-07-25 | 2020-02-25 | Northeastern University | Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof |
| TN2017000544A1 (en) * | 2015-07-31 | 2019-04-12 | Pfizer | 1,1,1-trifluoro-3-hydroxypropan-2-yl carbamate derivatives and 1,1,1-trifluoro-4-hydroxybutan-2-yl carbamate derivatives as magl inhibitors |
| WO2017087858A1 (en) | 2015-11-20 | 2017-05-26 | Abide Therapeutics, Inc. | Pyrazole compounds and methods of making and using same |
| CN108601769B (zh) * | 2015-11-20 | 2021-09-03 | H.隆德贝克有限公司 | 吡唑化合物及其制备和使用方法 |
| US10323038B2 (en) | 2015-11-20 | 2019-06-18 | Abide Therapeutics, Inc. | Pyrazole compounds and methods of making and using same |
| WO2017096315A1 (en) | 2015-12-02 | 2017-06-08 | The Scripps Research Institute | TRIAZOLE DAGL(α) INHIBITORS |
| DK3630744T3 (da) | 2017-05-23 | 2023-03-06 | H Lundbeck As | Pyrazol-magl-inhibitorer |
| JOP20190267A1 (ar) | 2017-05-23 | 2019-11-18 | Lundbeck La Jolla Research Center Inc | مثبطات بيرازول magl |
| US10927105B1 (en) | 2017-05-23 | 2021-02-23 | Lundbeck La Jolla Research Center, Inc. | Pyrazole MAGL inhibitors |
-
2017
- 2017-06-16 JO JOP/2019/0267A patent/JOP20190267A1/ar unknown
-
2018
- 2018-05-22 MX MX2019014041A patent/MX2019014041A/es unknown
- 2018-05-22 US US16/615,746 patent/US11149037B2/en active Active
- 2018-05-22 WO PCT/US2018/033964 patent/WO2018217809A1/en not_active Ceased
- 2018-05-22 CN CN201880033866.9A patent/CN110678177B/zh active Active
- 2018-05-22 BR BR112019024488-3A patent/BR112019024488A2/pt not_active Application Discontinuation
- 2018-05-22 CR CR20190537A patent/CR20190537A/es unknown
- 2018-05-22 ES ES18805515T patent/ES3005265T3/es active Active
- 2018-05-22 MA MA050405A patent/MA50405A/fr unknown
- 2018-05-22 EP EP18805515.6A patent/EP3634404B1/en active Active
- 2018-05-22 PE PE2019002453A patent/PE20200293A1/es unknown
- 2018-05-22 EA EA201992504A patent/EA201992504A1/ru unknown
- 2018-05-22 KR KR1020197037406A patent/KR20200010366A/ko not_active Withdrawn
- 2018-05-22 CA CA3065898A patent/CA3065898A1/en not_active Abandoned
- 2018-05-22 AU AU2018273888A patent/AU2018273888A1/en not_active Abandoned
- 2018-05-22 RU RU2019137094A patent/RU2019137094A/ru not_active Application Discontinuation
- 2018-05-22 JP JP2019565399A patent/JP7162622B2/ja active Active
-
2019
- 2019-11-20 DO DO2019000295A patent/DOP2019000295A/es unknown
- 2019-11-21 CL CL2019003398A patent/CL2019003398A1/es unknown
- 2019-11-21 CO CONC2019/0013016A patent/CO2019013016A2/es unknown
- 2019-11-22 PH PH12019502646A patent/PH12019502646A1/en unknown
- 2019-11-22 NI NI201900120A patent/NI201900120A/es unknown
- 2019-11-25 EC ECSENADI201983923A patent/ECSP19083923A/es unknown
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