NEW MATERIAL:The compound of formula (glu is β-glucopyranosyl group).
USE: A carcinostatic agent.
PREPARATION: The compound of formula can be produced e.g. by (1) dissolving whole saponin of Gynostemma pentaphyllum containing 2-α-hy droxyprotopanaxadiol saponin as main component in an aqueous solution of dihydrogen sodium phosphate or 4.0 pH, (2) stirring the mixture in the presence of a cellulase at 37°C for 24hr, (3) stirring for 6 days after the addition of aque ous methanol and cellulase, (4) passing the reaction liquid through an adsorbent column, (5) eluting the adsorbed component with methanol and (6) purifying the eluate by silica gel column chromatography.
Tigogenin cellobiosidforbindelser, to pharmaceutical compositions containing the compounds, use of said compounds for the preparation of a pharmaceutical composition and processes for preparing the compounds
Growth hormone releasing factor compounds, the compounds for use as a therapeutic agent, processes for preparing the compounds, to pharmaceutical compositions containing an effective amount of such a compound and the use of the compound