JPS63297363A - Production of 3-methylindoles - Google Patents
Production of 3-methylindolesInfo
- Publication number
- JPS63297363A JPS63297363A JP62129833A JP12983387A JPS63297363A JP S63297363 A JPS63297363 A JP S63297363A JP 62129833 A JP62129833 A JP 62129833A JP 12983387 A JP12983387 A JP 12983387A JP S63297363 A JPS63297363 A JP S63297363A
- Authority
- JP
- Japan
- Prior art keywords
- catalyst
- formula
- hydrogenation
- compound
- indole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ZFRKQXVRDFCRJG-UHFFFAOYSA-N skatole Chemical class C1=CC=C2C(C)=CNC2=C1 ZFRKQXVRDFCRJG-UHFFFAOYSA-N 0.000 title 1
- 239000003054 catalyst Substances 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 4
- 238000005984 hydrogenation reaction Methods 0.000 abstract 3
- OLNJUISKUQQNIM-UHFFFAOYSA-N 1H-Indole-3-carboxaldehyde Chemical class C1=CC=C2C(C=O)=CNC2=C1 OLNJUISKUQQNIM-UHFFFAOYSA-N 0.000 abstract 2
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 2
- 229910052751 metal Inorganic materials 0.000 abstract 2
- 239000002184 metal Substances 0.000 abstract 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 abstract 2
- KDLHZDBZIXYQEI-UHFFFAOYSA-N palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 2
- 239000002994 raw material Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- HPQVWDOOUQVBTO-UHFFFAOYSA-N lithium aluminum hydride Chemical compound [Li+].[Al-] HPQVWDOOUQVBTO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052759 nickel Inorganic materials 0.000 abstract 1
- 229910052763 palladium Inorganic materials 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62129833A JPH059427B2 (ja) | 1987-05-28 | 1987-05-28 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62129833A JPH059427B2 (ja) | 1987-05-28 | 1987-05-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS63297363A true JPS63297363A (en) | 1988-12-05 |
| JPH059427B2 JPH059427B2 (ja) | 1993-02-04 |
Family
ID=15019358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62129833A Expired - Fee Related JPH059427B2 (ja) | 1987-05-28 | 1987-05-28 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH059427B2 (ja) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998045261A1 (fr) * | 1997-04-07 | 1998-10-15 | Ihara Chemical Industry Co., Ltd. | Procede de production de 5-methylindolines |
| EP1325911A1 (en) * | 2002-01-07 | 2003-07-09 | SK Corporation | Method for preparing 3-methylindole derivatives through hydrogenation |
| KR100476359B1 (ko) * | 2000-08-31 | 2005-03-16 | 주식회사한국신약 | 벤자스타틴 유도체의 제조시 중간체로 사용 가능한 새로운화합물 및 그 제조방법 |
-
1987
- 1987-05-28 JP JP62129833A patent/JPH059427B2/ja not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998045261A1 (fr) * | 1997-04-07 | 1998-10-15 | Ihara Chemical Industry Co., Ltd. | Procede de production de 5-methylindolines |
| EP0976731A1 (en) * | 1997-04-07 | 2000-02-02 | Ihara Chemical Industry Co., Ltd. | Process for producing 5-methylindolines |
| EP0976731A4 (en) * | 1997-04-07 | 2000-05-24 | Ihara Chemical Ind Co | PROCESS FOR PRODUCING 5-METHYLINDOLINES |
| KR100476359B1 (ko) * | 2000-08-31 | 2005-03-16 | 주식회사한국신약 | 벤자스타틴 유도체의 제조시 중간체로 사용 가능한 새로운화합물 및 그 제조방법 |
| EP1325911A1 (en) * | 2002-01-07 | 2003-07-09 | SK Corporation | Method for preparing 3-methylindole derivatives through hydrogenation |
| KR100766616B1 (ko) | 2002-01-07 | 2007-10-11 | 에스케이 주식회사 | 수소화반응을 이용한 3-메틸인돌 화합물의 제조방법 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH059427B2 (ja) | 1993-02-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| S531 | Written request for registration of change of domicile |
Free format text: JAPANESE INTERMEDIATE CODE: R313531 |
|
| S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313117 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
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| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313115 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| LAPS | Cancellation because of no payment of annual fees |