JPS6185311A - Cleaning solution - Google Patents

Abstract

PURPOSE:A cleaning solution that contains, as an active ingredient, at least one of disinfectants readily soluble or relatively soluble in water and is used in the form of a diluted solution to clean around anus or inhibit proliferation of undesired microorganisms. CONSTITUTION:A hygienic composition containing at least one of disinfectants soluble or relatively readily soluble in water or a combination thereof with at least one of water-soluble surface active agents is diluted to a concentration for ready use to give the objective cleaning solution. The disinfectants used in this invention are, e.g., 1,6-di-(4'-chlorophenyldiguanide)hexane, gluconate salts, alkyldimethylbenzyl ammonium chloride or cetyltrimethylammonium bro mide. The solvent for dilution is mainly water, but the water can be combined with a water-soluble organic solvent such as ethanol or glycerol. The solvent is used by having allowable products absorb it in an appropriate amount.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention provides a water-soluble or relatively water-soluble disinfectant;
Or, it is related to a cleaning solution used for cleaning the anal region of the human body, which is a solution prepared by diluting a drug containing a surfactant to a working concentration.
It is said that there are seven people per person. The reason for this large number of
Although it may be due to a constitutional problem, it is also said to be caused by the intake of grains and lifestyle. Other reasons why so many people suffer from this problem include the fact that the affected area tends to be relatively unhygienic, and the area is a place where people feel reluctant to receive treatment from a doctor.

Many drugs have been researched and developed for the treatment of hemorrhoids, including surgical methods, and considerable results have been achieved since ancient times, but the issue of cleaning the area around the anus after defecation has not received much attention. Apparently not.

Recently, devices that spray hot water from household toilet bowls, especially Western-style water heaters, to clean the anal area after defecating have become popular.This method is a great improvement compared to the conventional use of toilet paper. It can be said. Regular use of this device prevents the affected area from getting worse due to irritation,
This is thought to have a positive effect on the therapeutic effect.

However, this device currently appears to be mostly confined to the home. Such devices are rarely installed in toilets used on business trips or trips.

In such cases, an alternative method is required.
For people suffering from hemorrhoids, daily defecation is said to be the most painful moment, and the current situation is that they are forced to use toilet paper while thinking that it is bad.

The inventor of the present invention has been researching on disinfectants that can be used safely by anyone in such cases, and as a result, he has identified water-soluble or easily water-soluble disinfectants that are highly safe for the human body, and has identified the characteristics of each disinfectant. We discovered a method for cleaning the anal area and keeping it sanitary by carrying a solution diluted to the concentration calculated based on its sterilizing power.

If you carry it with you, use a diluted cleaning solution in a portable air bottle, a manual injector, or an aerosol container. Although it can be sprayed for cleaning purposes, it can be applied to the affected area by layering toilet paper to some degree, or by absorbing an appropriate amount of cleaning solution from each container into a textile product that can be flushed down the flush toilet, such as pocket paper or dust paper. It can be used for cleaning.

Paper products used after defecating, such as toilet paper, have an extremely weak wet strength so that they can be flushed down the flush toilet, but their dry strength is quite strong. (This can cause irritation, resulting in insufficient cleaning, and can also cause negative effects.

When an appropriate amount of the cleaning solution of the present invention is absorbed into a textile product that can be used individually, such as toilet paper, it becomes soft due to moisture, making cleaning easier without irritating the affected area too much. In addition, the sterilizing effect of the cleaning solution can prevent the growth of pathogenic bacteria and other germs, which can maximize the efficacy of therapeutic drugs and further enhance the healing effect, which is great news for patients. Keeping the liquid in the household toilet and using it in conjunction with hot water washing will lead to even better results.

The skin around the anal area of the human body is a very weak outer layer and is also sensitive to drugs, so the main component of the cleaning solution used here must be a particularly safe substance. Of course. Bactericidal agents that can be used in the present invention, such as /, di(4t+-chlorophenyldiguanide)hexane, gluconate, alkyldimerpendylammonium chloride) (R=Cs~1B), cetyltrimethylammonium bromide , dodecyldiaminoethylglycine 1.LQ4tI-)IJ chloroco-1-hydroxydiphenyl ether, etc., which are water-soluble are preferable, but substances that become water-soluble when combined with a surfactant and are relatively easily water-soluble can also be used. One type or two or more types of agents can be blended.0 Furthermore,
Surfactants can also be used in combination with these disinfectants. Addition of a surfactant has advantages such as making the drug water-soluble, providing permeability, detergency, and flexibility. As the surfactant, nonionic, anionic, cationic, and amphoteric surfactants, all of which are water-soluble, can be used.

For example, pentasaccharide higher fatty acid monoester, fatty acid dialkanolamide, polyoxyethylene alkyl allyl ether, polyoxyethylene alkyl ether, etc.

The disinfectants used in the present invention are dissolved in water and diluted to the lowest dilution ratio depending on the antibacterial activity of each disinfectant. The solvent used for dilution is mainly water, but
Water-soluble organic solvents such as ethanol, ethylene glycol, and glycerin can also be used in combination. It can also be used as an emulsion that is close to solubilization.

This will be explained below using examples.

Examples Various formulations were made using various fungicides and various surfactants, and fungicidal efficacy tests were conducted on each of them.The results are as follows.

This formulation is at a concentration that can be used as a cleaning agent.

Notes/Bactericide used in formulation example 11) l 6-C(4t'-chlorophenyldiguanide)hexane.

Gluconate (2) Benzalkonium chloride (Japanese Pharmacopoeia product)
(3) Cetyltrimethylammonium bromide (
4) Dodecyldiaminoethylglycine hydrochloride (512K
Surfactant using I-trichloro-21-hydroxydiphenyl ether (Allll Nastearic acid monoester l Pholioxyethylene cetyl ether (, wg,
o, ) (Cl polyoxyethylene sorbitan monooleate (-2θg, o,) [Note] The number is chi.

Test method for testing the bactericidal efficacy of detergents The liquid cultured test bacterial solution/go was mixed with each prescribed drug/θ and left at 30°C for 70 minutes, then a certain amount was taken with a pipette and heated to dissolve agar. The mixture was mixed with the culture medium in a Petri dish so that it was uniform.

After the agar medium solidified, it was incubated in a 30"C incubator for 2 hours.
The number of test colonies that grew was calculated and the rate of bacterial reduction compared to the control was determined. As a control, sterile water was used instead of the chemical solution.

Test bacteria used: A! 1taphyloaoaus aur*
um 209 FB, E*eh@riehora
ali K-12c, P-eudemoms a@
rughosa k4D, Baulus
subtuim POX test results Bacterial reduction rate (%)

Claims (2)

[Claims] (1) One or more water-soluble or relatively water-soluble disinfectants, or one or more water-soluble surfactants.
What is claimed is: 1. A cleaning solution comprising a diluted drug or a combination of two or more species to a working concentration and used for cleaning the anal region of the human body. (2) The cleaning liquid according to claim 1, which is used by being adsorbed onto a textile product usable for toilet paper or flush toilets.