JPS6168563A - Fully automatic chip supply feeder/inserter distributing apparatus - Google Patents

Abstract

PURPOSE:To avoid the mingling of samples, by performing an fully automatic feeding and insertion of chips into a distribution pump nozzle. CONSTITUTION:A magazine mechanism A performs a pitch conveyance of a magazine box 1 along a guide plate 2 which supportively guides the lower end of a beta group of continuous chip insertion bodies ejected out of a release hole 1c piercing the bottom 1b. A slide mechanism B has drop holes 3a and 3b piercing a slide plate 3 to release the lower end of a continuous chip insertion body beta from the support and let it drop by its own gravity. A grasp/separation mechanism CD receives and grasps the lowest chip alpha of the continuous chip insertion body beta dropping through drop holes 3a and 3b once with grasping pieces 6 and 7 and drops one at a time sequentially from bottom gradually to separate by alternately opening and closing the grasping pieces 4 and 5. A transfer mechanism E transfers a holding plate 8 receiving a chip alpha with receiving holes 8a and 8b to the chip inserting position. A distribution pump lift mechanism F forcibly inserts the tip of each nozzle 10 of a distribution pump 9 into itself and lifts up.

Description

[Detailed Description of the Invention] [Industrial Field of Application] The present invention is applicable to biochemical analyzers, epidemiological examinations for cancer, etc., serum testing machines, etc. by injecting a fixed amount of a sample into a test tube or test piece. This invention relates to a device that fully automatically performs tip supply/insertion work in a dispensing machine used for.

[Prior Art] This type of conventional dispensing work was carried out by a female worker using a manual pipette. Even with advanced automated machines, sample aspiration is possible! Although the extraction and movement of test tubes were done automatically, there was no system that automatically inserted a new tip into the nozzle that aspirated and dispensed a quantitative amount of the sample.

In other words, in the dispensing process, the most important issues to be aware of, as well as strict quantitative dispensing of the sample, are when dispensing Tatsumi type samples using the same nozzle, and when dispensing extremely dangerous factors such as hepatitis bacteria. Never mix contact with other specimens [J
Must be. When using a manual pipette, a new tip was inserted in advance, and each time the sample was changed, the used tip was pulled out by hand and discarded, but when the tip was removed, it stuck to the hand. There was a problem in that the small amount of sample could contaminate and stain the chip that was newly inserted. In addition, in the case of automatic dispensing machines, the nozzle tip is fixed, so the inside and outside parts are washed with water or air, or rubbed with paper or a brush to prevent mixing. Complete extermination of remaining porpoises can be achieved with this level of precision 7'I'I treatment (, 1,
Impossible, interbreeding in the strict sense could not be prevented, and there was no effect of the Song era on culms exchanging tips.

Moreover, when replenishing the magazine mechanism of the automatic dispensing machine with chips, ■Pinch the chips one by one by hand, ■Insert the chips one by one to form a predetermined number of chips, Insert the serial insert into the magazine mechanism.

It is troublesome and time-consuming because the operations described in 1) have to be repeated multiple times, and the feeding/insertion/loading direction cannot be operated during ①, which is extremely inconvenient. In addition, bacteria or dirt may adhere to the tip that you touch during the operation of ■, or you may insert a different kind of similar lump during the operation of ■. There is a risk that foreign substances may be mixed in.

[Problems to be Solved by the Invention] Therefore, in view of the seriousness of the mixing that must be avoided, the present invention provides a cassette containing a sufficient number of chips to accommodate the number of test tubes set on a dispensing work table. Easy to set and place, effective for automatically and continuously supplying new tips one by one to the tip of the dispensing nozzle as the dispensing process progresses. Fully automatic tip in an appropriate dispensing machine. A supply insert is provided in the stomach.

[Means for Solving the Problems] A first embodiment of the present invention will be described with reference to FIGS. 1 to 3.

The device of the present invention is equipped with a dispensing tip cassette γ in which a plurality of tip inserters β into which a predetermined number of tips α with two-stage flanges α1 are vertically loosely inserted are housed in parallel rows at equal pitches p.
At least one (two are shown in this example) is inserted into the bottom part 1b of the magazine box 1, which is inserted and replaced in the magazine box 1. The magazine mechanism Δ, which pitch-transfers the magazine box 1 along the guide plate 2 that supports and guides the lower end of the chip series β group that has been taken out, is inserted between the central part of the guide plate 2 and moves back and forth intermittently. When the freely installed slide plate 3 is in the most retracted position, the chip connecting body β is positioned and stopped on the slide plate 3, and the lower end of β is released from support and the chip connecting body β is moved.

Pithole 3 with mutual 2 pitches and 2p spacing where β falls vertically under its own weight
a slide mechanism B in which a and 3b are installed through the slide plate 3;
Immediately below the slide plate 3, a pair of clamping pieces 4, 5, 6, 7 at the front and rear of the loli are provided on the upper and lower stages of the lx, respectively, so as to be able to open and close freely. The lowest chips α and α of β are clamped by the pair of clamping pieces 6.7 on the lower stage of 18, and then the pair of clamping pieces 4°5 on the first stage are held.
The tip connecting body β, the tip α of β, are opened and closed alternately.
The upper and lower staged clamping portion M mechanism C1D moves α one by one from the top and separates it, and the lower stage and clamping portion 1
11 Machines stopped directly under 4MD, 1 waited, vertically separated, and the falling chips α and α were placed in receiving holes Ba with 2 pitches and 2p spacing from each other.
A transfer mechanism capable of reciprocating intermittently that transfers the holding plate 8 held by the tip 8b to the stomach in the chip insertion work position and stops at the position [and a chip α held and waiting in the neck of the chip insertion work position] , each nozzle 10 of the dispensing pump 9°9 from α Masato.
It consists of a dispensing top 4 lowering mechanism F which is inserted and raised by pushing in the tip of the dispensing machine Y, and is installed and installed at the positions shown in FIGS. 4 and 5 of the dispensing machine Y, respectively.

In the figure, ε is a test wA tube set up in the dispensing work rack δ.

, As shown in FIGS. 1 and 6, the magazine mechanism A is
A feeding means A1 that reciprocates horizontally along the guide plate 2, a locking means A2 that immovably fixes the positioning stop +L,
A first support and guide means A3 and a second support and guide means A4 for smoothly supporting and guiding the magazine by regulating vertical, horizontal and forward vibrations during horizontal conveyance are installed on the side of the magazine box 10.

The feeding means Δ1 has a belt clamp 11 protruding from the center of the back side of the magazine box 1, and a pair of left and right subarees 12.
13 Sideways over the top and both ends 1) Forward channel 1
A D retiming belt is provided between a protruding shaft 15 protruding toward the left end of 4, a driven timing pulley 16 protruding so as to freely rotate, and a pulley ll1l through-supporting the pulley 17 so as to freely rotate toward the right end.17 A driving timing pulley 18 fixed to the front end. The large timing pulley 20 and pulse motor 21 are fixed to the rear end of the pulley shaft 17.
The timing bells 1 to 24 are endlessly stretched between the small timing pulleys 23 of the same size on the outer end of the motor shaft 22.
On the other hand, by attaching the belt clamp 11 to one location on the upper side of the timing bells 1 to 19, the pulse motor 21
Rotate 1 to 100 mph with timing bell I-24, large timing pulley 20. Pulley 111! l 17 , the magazine box 1 is horizontally moved from side to side via the original timing pulley 18 and timing belt 19 = 11 = .

The first support guide means A3 includes roller shafts 25 and 26 that protrude horizontally and diagonally upward and downward from the upper part of the back side of the magazine box 1.
An abacus bead-shaped guide roller 27 and a backup roller 28 are attached to the tips of the stand frame 29 so that they can freely rotate. It is clipped in so that it can be moved freely.

The second support guide means 4 has a slide block 32 with a slide groove 31 horizontally attached to a predetermined location on the lower side of the back side of the magazine box 1, and extends cantilevered over the entire length of the lower side of the channel 14.
Shape guide rail 33 hook part 3'3a''] direction slide full 3
1.

The locking means A2 is attached with a gauge 34 having a roller positioning group 34a engraved on the back side of the magazine case 1 directly above the belt clamp 11, and on the other hand, on the channel 14 and in the stand frame 29. One end of an L-shaped bar 39, whose central portion is pivotally fixed to the frame plate 35 with a fulcrum step screw 38, is pivotally connected to the outer end of the movable core 37 of the solenoid 36 installed laterally near the rear end of the plate 35. At the same time, the other end of the intermediate link/11, whose one end is pivotally connected by the connecting screw pin 40 to form a center-folding type 1~guru mechanism near the other end, is attached with its base end as a fulcrum near the front end of the frame board 35. The tip of the lock 1 flange 43 is pivotally fixed with a screw 42, and is pivotally connected with a connecting screw pin 44 toward the tip bending die 43a, so that it can freely engage in the positioning part 34a. facing the other end of the 1-shaped lever 39 and the plucking pin 45 set up on the frame plate 35.
At the same time, the retractable strip 46 is stretched to urge the movable iron core 37 to move out and the bending claw 43a at the tip of the lock lever 43 to move into the positioning position 348. As shown in Fig. 8, the front bending claw 43a is positioned and pulled out from the position 34a against the elastic tensile force of the return plucking strip 46. The +34a group is a cassette γ inserted into the insertion stock chamber 1a of the magazine box 1.
, corresponding to the group of chip connecting bodies β built in parallel in a row at a pitch p interval in γ and the extraction hole 1C group arranged at a pitch p interval of the magazine box 1, and repeating the 1:3:1:3 pitch p. It is provided in the relevant position.

FIG. 9 shows a magazine mechanism A' in which one cassette γ can be inserted and accommodated, and the same parts as the magazine mechanism A are given the same reference numerals.

As shown in FIGS. 10 and 11, the slide mechanism B has a slide hole 3C in the front center protrusion on the slide 47 and a pair of left and right slide holes 3d on the rear side.

3e is attached with guide step screws 48, 49, 50 so as to be slidable back and forth, and a pair of left and right drop holes 3a are spaced apart from each other by two pitches on the front half side.

The other end of the short link 52, whose one end is pivotally connected to the center of the rear end of the slide plate 3 with a connecting screw pin 51, is placed near one end of a lever 54 whose center is slightly movable with a fulcrum screw 53. The lever 54 is pivoted to the outer end of the movable core 58 which is inserted into the solenoid 57 mounted on the pedestal 56, while being pivotally connected by the connecting screw pin 55.
On the other hand, stand 411'I on one end of the lever [2] and the pedestal 560. By tensioning the first pin 60 with a retractable spring 61, the outgoing behavior of the movable iron core 58 and the backward movement F4 of the slide plate 3 are controlled, and the slide plate 3 is at the last position of about 3 μm. ! The tension bullets (11
The slide plate 3 is configured to move forward against the force.

Shown in Figure 12 1J: Separator with a lower groove on the - side and a clamping separator +i
4C and D are a pair of front and rear upper and lower stage clamping pieces 4, which are freely held in the front and back so that they can be opened and closed, and 5. 6. 2 pitches 2r that can freely hold the lower side of the lower flange α1' of the lowest chip α on the lower side of the flange α1'' and the relative edges of the lower clamping pieces 6 and 7;
) A pair of left and right semicircular holes 4a, 4. b
, 5a, 5b.

6a, 6b, 7a, and 7b are provided opposite each other, and the lower FQ No. 1 right-acting 1-stage CI is provided at both the left and right ends of the upper means front and rear clamping pieces 4, 5, 6.7 to operate the front and rear separation opening and closing movements. C2,r
) 1, C2 are respectively installed I:J, and the front and rear clamps 4, 5, 6.7 of the upper means can be freely opened and closed in alternating directions.

C2 is constituted by a single-disk groove cam opening 2 that can be freely controlled in drive.

As shown in FIGS. 13 to 14, the lower left/right operation unit DI, C2 is an upper floor board 63 which is rotatably penetrated.
A disc groove cam 62 fixed to a cam shaft 65 between the upper floor plate 64 and
The cam follower 66, which engages with the cam groove 62a of the cam groove 62a, is freely rotatable at the first corner. One end of the link 69 is pivotally connected to the third corner of the triangular lever 68 with a pin 70, and the other end is pivotally connected to the first corner of the triangular IJ+ lever 71 with a connecting screw pin 72. ], lower floor board 6
A relay pin 74 and a freely rotatable right rear trochanter 75 are protruded from protrusions 71a and 71b on both sides of the second corner of the triangular interlocking lever 71, which is movably fixed to the fulcrum screw 73 at 4. A medium flame is pivotally fixed to the lower floor board 6/I with a fulcrum screw 76, and the other end of the 1-shaped lever 77, which has one end bifurcated portion 77a and is connected with the relay pin 74, is freely rotatable. While protruding the right front trochanter 78, the upper end is pivotally attached to the third corner of the triangular interlocking lever 71 with a retaining screw 79, and the elongated hole 64 of the lower floor plate 64 is
The other end of the first intermediate link 82, whose one end is pivotally connected to the lower end of the short shaft 80 passing through a with a retaining screw 81, is connected to the lower floor board 6 with its center part.
4. Pivotally connected with a connecting pin 86 to one end of an intermediate lever 85 which is pivotally fixed on the lower side with a fulcrum screw 84 via a crosspiece 083,
On the other hand, the other end of the second intermediate link 88, whose one end was pivotally connected to the other end of the intermediate lever 85 with a pin 87, was pivotally connected to the lower end of the second intermediate link 88 with a screw 89, and passed through the long hole 64b of the lower floor board 64. Short axis 90
- One end of a 1-shaped lever 92 whose center portion is pivotally fixed to the lower floor board 64 at the upper end with a fulcrum screw 91 is pivotally attached with a retaining screw 93, and a relay pin 94 is attached to the other end and the central tip, respectively. The left front trochanter 95, which can be rotated freely, is protruded, and the central part is pivotally fixed to the lower floor plate 64 with a fulcrum screw 96, and the other end of the 1-shaped lever 97, which has a two-pronged balance portion 97a connected to the pin 94, is rotated freely. Protruding freely adjustable posterior trochanter 98, left and right front and rear trochanters 75.7fl
.

95.98iY The guide protrusion 99.100 of the lower floor board 64 faces each other to the left and right symmetrical movement white A1, and can be opened and closed forward and backward.
left and right tii6d, which are respectively missing at both left and right ends of a pair of front and rear clamping pieces 6.7 with slide holes 6c and 7c left open;
Left and right anteroposterior trochanters 75 corresponding to 6e, 7d, and 7e, respectively
J:
Holes 6/IC, 64d are formed in the lower floor board 64 at positions corresponding to the semi-circular holes 6a, 7a, 6b, 7b closed by the front and rear clamping pieces 6, 7, respectively. It becomes.

In the figure, reference numeral 101 denotes the front and rear clamping halo, and the upper restraining part +4 of 7.

Further, a pinion 103 that externally meshes with a driven shaft 102 fixed to the lower end of the camshaft 65 is fixed to the upper end of the motor shaft 106 of the motor 105 fixed to the table frame 104.

-18= The first stage left and right operating means CI, C2 are as shown in FIG. ) As shown in the figure, the disc groove cam 62 cam full 6'2a
The force 11 of the cam wheel 107, which engages with the follower 66 at a position 180° opposite, is attached to the first corner so that it can freely rotate 441-J
1. Attach the second corner to the lower floor board 64 with the fulcrum step screw 108 knee ('
One end of the link 110 is fixed to the third corner of the 1+1 movable triangular collar 109, while the link 11
A triangular interlocking lever 111 is attached to the upper end of a short shaft (not shown) whose lower end is pivotally connected to the other end of the 0, and which passes through the notch 63a of the upper floor board 63.
The first corner of the triangular interlocking lever 111 is pivoted with a pivot 112, and the second corner of the triangular interlocking lever 111 is pivoted and fixed to the upper floor board 63 with a fulcrum step screw 113. A relay pin 114 and a rotatable left rear trochanter 115 are protruded from each of the pieces 111a and 111b, and the center is a fulcrum stepped screw 1.
At the other end of the 1-shaped 1-flange 117, which is pivotally fixed to the upper floor board 63 at 16 and has a bifurcated end and 1 part 117a connected inward to the relay pin 11/I, a freely rotatable t' is attached to the other end. child 118
At the same time, the upper end is inserted into the third corner of the third f0 interlocking first collar 111 with a pivot screw 19, and the short shaft 120 passing through the long hole 63b of the upper floor plate 63 is inserted into the lower end. The other end of the first intermediate link 121, whose one end is pivotally connected with a retaining screw (not shown), is connected to the lower floor board 6 at the center part.
3. A connecting pin 12 is attached to one end of an intermediate lever 1211 which is pivotally fixed to the lower side with a pillow member 122 and a fulcrum step screw 123 for fine movement.
5, the other end of the second intermediate link 127 is pivotally connected to one end with a connecting pin 126, and the other end of the second intermediate link 127 is pivotally connected to the lower end, and a short shaft 128 passes through the long hole 63C of the upper floor board 63. One end of the 1-shaped lever 130, whose center portion is pivotally fixed to the upper plate 63 with a fulcrum step screw 129 so as to be able to move freely, is attached to the upper end by the screw 13.
1, and a relay pin 132 and a freely rotatable right front trochanter 133 are protruded from the other end and the center tip respectively, and the center part is pivotally fixed to the upper floor board 63 by a fulcrum step screw 134, and one end is bifurcated. 1-type lever 1 with portion 135a connected to pin 132
A right rear trochanter 136 which can freely rotate freely is protruded from the other end of the 35, and left and right front and rear trochanters 115, 118, 133, 136 groups phase n are symmetrically movable and face each other 1), and the upper floor board can be opened and closed forward and backward. 6
Slide holes 4c and 5 in the guide protrusions '137 and 138 of 3.
Left and right transfer grooves 4d have grooves on both left and right ends of the pair of clamping pieces 4.5 on the front 1st rim into which the holder 4.c is loosely fitted.

/le, 5d, 5e (corresponding left and right anteroposterior trochanter 1)
15, 118, 133, 136 are stacked together and are linked to follow one rotation of the disk groove cam 62.
, 7 is rotated by 180 degrees and opens and closes by 1, and the front and rear clamping pieces 4.5 in the V corner plate 63 have closed half-circular holes 4a and 7, respectively. :) Holes 63d and 63e are provided through holes 63d and 63e at positions corresponding to a, 4b and 5b, respectively.

In the figure, 139 is an upper restraining member for the front and rear clamping pieces 4.5.

As shown in FIGS. 1 to 3, the transfer 1gJE is
Jz is detected by the lenser SO in the abdication direction, and f・F −
＋L i The lower groove is opened and the lower flange α1' of the chips α and α are received by the support 11.
- Insert and hold the receiving holes 8a and 8b with 2 pitches 2p phase n
A holding plate 8 with one lever provided at intervals is fixed, and ta=transfer body L.
4 (1), a guide means for guiding and regulating the transfer body 140, and a feed f stage F2 to t for conveying the transfer body 140 along the guide means E1. 11, the proximal end is cantilever-fixed to the upper end of the transfer body 140, and the light projector L1 and the light receiver 1-2 are embedded facing each other in the diametrical direction of the inner peripheral surface of the receiving holes 8a and 8b, respectively, and the guide Means F1 is a table frame 104
A guide rod 143 extends in the front-rear direction inside the transport body 140 and passes through the slide holes 141a and 142a of the front-rear slide blocks 141 and 142 of the transfer body 140 so as to be slidable in the axial direction. It consists of a guide beam 145 that is slidably loaded in the axial direction by a loading slide piece 144 fixed to the lower end of the plate 8, and a receiving hole of the holding plate 8 is provided at the most forward position of the holding plate 8 at one end. A chip insertion work rod 146 for lowering the lower side between 8a and 8b is erected on the base frame B on the front side between the table frames 104 and 104.

The feeding means F2 is freely rotatable on the front end side between the guide rod 1/I3 and the guide shaft 45.
The shaft 17I9 is fixed to one end of the timing bell I-15 along a parallel line between the mouth guide rod 143 and the guide beam 145 between the dynamic timing pulley 150.
1 is stretched endlessly, and a belt clamp 153 attached to the lower plate 152 of the transfer body 140 is attached to the upper row of the timing bells 1 to 151.

As shown in FIGS. 3 to 5, the dispensing pump lowering mechanism F is
The table frame 1071 is erected near the front of the middle of the soil.One end is fixed to the A-le frame 154 and the guide beam frame 155 extends horizontally in a cantilever forward direction. A pair of left and right hanging shafts 158 and 159 are movably mounted and the dispensing bongs 19 and 9 are respectively attached 1), and are suspended in parallel at a predetermined interval, and the outer circumferences of the hanging shafts 158 and 159 are carved in the axial direction of the 1 side. The pinions 1 fit into the extended racks 158a and 159a, respectively.
60.161 to reversible motor 156.157 shaft 162.
163 Fixed to the outer end of the guide beam frame 15! ′
) to d) Chip insertion work + 1146 uppermost part) i
E (hanging shaft 158, 1b9 that went to the +1 hole) φ7-ter 156.157 is driven in normal rotation and vertically lowered, and the holding plate is already placed on the chip inserting work column 146. In the chips α and α held in the receiving holes 8a and 8b of No. 8, respectively,
After pushing the tip of the nozzle 10 attached to the lower surface of the dispensing pump 9, 9 to the lowest position and inserting the tips α, α,
Each of the reversible motors 156 and 157 is driven in reverse and is configured to vertically rise 1! to the 1st limit position.

Incidentally, the descendant operation timings and operation command signals of each mechanism A to F of the fully automatic chip supply/insertion apparatus of the present invention provided in the dispensing machine Y are sent to a combination coater or a sequencer.

[Function] Since the present invention is configured as described above, prior to starting the device of the present invention, the magazine box 1 is fitted into the slots 1 to 1. Remove the cassettes γ and γ from 1a, insert them into the 7I-2/I- and set aside the seal tape T wound on the outside.

First, the magazine mechanism △ smell-C1 pulse motor 21 is driven, and the timing belt 19 is pitch-fed to integrally move the magazine box 1 onto the guide member 2 while being guided and regulated by the first support guide means A3 and the second support guide means A4. , cassette 1~γ
, when the magazine box 1 reaches the rightmost position by supporting and sliding the lower end protruding from the 11 outlet hole 1C group of the magazine box 1 bottom 1b of the chip connecting body β group loaded and housed in γ.
When the solenoid 57 shown in the figure is demagnetized, the movable iron core 58 moves outward under the action of the tensile elastic force of the return repellent strip 61, so the slide plate 3 moves to the most retracted position, and the left and right drop holes 3a and 3b are opened from the right side. Since the first and third chip joint inserts β and β coincide with the lower ends, the chip joint inserts β and β lose their support and fall vertically downward under their own weight from the left and right drop holes 3a and 3b, and the second As shown in the figure, the four lower bumps α, α on each of the inserts β, β are formed into lower grooves by the rotational position of the disc cam groove 62 shown in FIG. 13 at this stage. Phase 7
'7111 Front and rear clamping pieces 4.5 semicircular holes / Ia
and 5a, 4b, etc.i) semicircular holes 6a and 7a of the front and rear clamping pieces 6, 7, which pass between the lower groove and the clamping part 111 mechanism to close the mechanism;
The lower side of each lower flange α1' is clamped by the receiver 1 at 6b and 7b, and the further rotational displacement of the disc grooved cam 62 causes the lower groove to be held, and the front and rear clamping pieces 4 and 5 of the mechanism C are Phase n approaches and closes semicircular holes 4a and 5a, 4b and 5b''('Tip continuous insert β, second tip α from the bottom of β.

Place the lower side of each upper flange α1'' of α into the clamping receiver IF, then move the lower side of C゛to the lower clamping portion ll! 1 mechanism front and rear clamping J”i'6. ．． 7
Phase n is released and the grip is released, and the lowest chip α is released.

α is lowered by 11FA due to its own weight, and the lower part of the lower tsuba α1' of the chips α and α that have separated and fallen is brought down to the maximum tG 3! u (</
When the sensor SL is directly detected by the sensor SO and held in the receiving holes 8a and 8b of the holding plate 8, the sensor SL
, The pulse motor 11'18 is driven by the light interruption detection signal of the emitter and receiver of S2, and the timing belt is 1°5.
1, the transfer body 140 is connected to the tensile rod 143. The chip is moved forward along the guide beam 1/15, and at the most advanced position, the chip is inserted between the receiving holes lea and 8b of the holding plate 8, and the chip is stopped at the work column 146, and then the chip is inserted into the work column 146. The chips α and α held in the receiving holes 8a and 8b of the holding plate 8 on the 1/I6 are brought to the center and the hanging is stopped moving along the guide beam frame 155 up to about 1!2jρ. axis 1
5B, 159, the reversible motors 156 and 157 are driven in normal rotation to rotate pinions 160 and 161 and racks 158a and 15.
Gradually descends by 1 due to the meshing relationship with 9a, nozzle 10.10
Insert the tips into the tips α, α, and press firmly at the lowest position Iv to insert the tips α, α into the tips of the nozzle 10.10, then drive the reversible motors 156, 157 in the reverse direction and move the C suspension shaft 158. 159 upper back +! L/Male nozzle 10.10 Hold the tips α and α in the tip of the nozzle 10 [receiving hole 8
When it is pulled out from a and 8b, the transfer body 140 is moved back along the guide rod 143 to the position 1 and 8b.

Now, after the lowermost chips α and α have been separated by the first upper stage and the clamping separation mechanisms C and D, the upper grooves are formed and the front and rear clamping pieces 4.5 of the clamping mechanism 11 are closed close to each other and the upper grooves are closed. The front and rear clamping pieces 4゜5 of the clamping separation mechanism C are separated, and the lower part of the lower flange α1' of the chips α and α, which are now at the lowest level, is grooved in an upper stage, and a semicircular hole with a clamping capacity of 11 tlfi is formed. 6a and 7a, 5b and 7b
Hold the receivers +F respectively, and thus separate the upper and lower clamping and separating mechanisms C and D by alternately opening and closing them to open and close the chip connecting bodies β and β.
The chips α and α are moved down and separated one by one from the bottom, and at the same time, the rightmost and third chip connecting bodies β and β-most chips α and α in the magazine mechanism A are After the light is completely submerged through the pit holes 3a and 3b, if the light emitter and light receiver of the lenses installed in the left and right receiving holes 8a and Bb do not emit a light shielding detection signal even after a predetermined period of time has elapsed, Demagnetize the solenoid 36 in Figure 7 and return to the closed rack 4
6, the bent tip 438 of the lock lever 43 is removed from the positioning groove 34a of the gauge 34, and the magazine box 1 is released. At the same time, the solenoid 57 shown in FIG. Move plate 3 back to the most forward position 9i+1')'ij, and use the pulse motor shown in Figure 1 to
21 is driven () to advance magazine box 1 by 1 pitch p η
If so, the 2M and 4th extraction holes 1c from the right.

A chip series 1 flr body β whose lower end is exposed from the I ch eyes,
β is positioned on the slide plate 3 and stops +L L, the solenoid 36 is energized again and the plucked line 1 is returned! I6 tension bullet f1
Resisting the force, the bent tip 43a of the lock lever 43 is engaged with the positioning groove 34a of the gauge 34, the magazine box 1 is immovably fixed, and the solenoid 57 is moved to the slide plate by the action of the return closing rack 61. If 3 is the last! (It is brought to the fI position and dropped from the pit holes 3a and 3b. In other words, the light shielding detection signals from the light emitters and receivers of the first and second lenses 81 and 32 installed in the left and right receiving holes 8a and 8b are also received after a predetermined period of time. Despite the fact that the 4i is 1.1 [!], solenoid 36
．． 57 is excited to drive the pulse motor 21 to obtain the number of pitches (Ill) in the pre-scheduled program.
The magazine box 1 is moved forward by 1 pitch (repeat alternately by 3 pitches), and at the same time as the positioning stop 1-, the solenoid 36 is activated.
．． 57 is demagnetized, the magazine box 1 is locked, and the sliding plate 3 is set so that the tip connecting bodies β and β are vertically dropped into the drop holes 3a and 3b.

In the embodiment of the present invention, two chip connecting bodies β,
Although we have exclusively explained the simultaneous parallel processing of β and two chips α and α separated from it, this is not the only example.
1 chip connecting body β and 1 chip α separated from each
Of course, the present invention also includes the case where two or more are processed in parallel.

Also, chip dock replenishment to magazine box 1 is done using cassette γ.
Since this method is adopted, it can be completed quickly with just a few operations, greatly simplifying stock replenishment work, etc., allowing one operator to operate several dispensing machines. Not only that, when replenishing the stock, there is no need for the operator to touch the chips at all, and there is no need to worry about chips similar to Tatsumi scales being mixed in, which reduces mechanical breakdowns, and replenishes the chip dock. Eliminates various inconveniences associated with work and also transports chips.

= 30-i^ pipe and 51 number management and inventory management can be done easily and reliably.

J: Sea urchin In the present invention, the operation of supplying and inserting chips into the dispensing pump nozzle after replenishing chips 1 to 4 is fully automatic and does not involve any operator's hands.
Prior to dispensing, a clean tip can always be inserted into the dispensing pump nozzle light cutter. This makes it possible to avoid contamination, as well as risk of worker infection due to frequent contact with specimens. By dividing the number by ljl, however, the present invention allows for simultaneous processing of multiple units, thereby streamlining and increasing the efficiency of the molecule lfl' process.

It has excellent effects such as efficiency, safety, labor saving, labor saving, mechanization, high speed, and multi-processing.

[Brief explanation of the drawing]

FIG. 1 is a partially omitted schematic perspective view of a magazine mechanism, a slide mechanism, a vertically arranged clamping and separating mechanism, and a transfer mechanism;
Fig. 2 is a diagram of the metering relationship, Fig. 3 is a front perspective view of main parts of the transfer mechanism and dispensing shaft pump lowering mechanism, and Figs. 4 and 5 are of a dispensing machine incorporating the device of the present invention. Side view and partially broken I
6 is a side view of the magazine mechanism, FIGS. 7 and 8 are explanatory diagrams of the f1 movement state of the locking means as seen diagonally from behind, and FIG. 9 is another embodiment of the magazine mechanism. 10 to 11 are a plan view and a side view of the slide mechanism, FIG. 12 is a schematic explanatory diagram of the upper and lower stage left and right operating means, and FIG. 13 is a plan view of the lower clamping and separating mechanism. 14th
The figure is an assembled side view of the upper and lower stacked clamp separation mechanism, and FIG. 15 is a top view of the upper and lower stacked clamp separation mechanism. α...Tip C1...-Katatsuba α1″...
1-One piece tsuba α1'...Lower piece tsuba β...Tip continuous insertion body γ...Cassette] ~ p...Pip A, A
'... Magazine mechanism AI, E2... Feeding means A2... Locking means A3... First support guide means A4... Second support guide f stage B... Slide IN
IMC...lower position and clamping share # Mechanism D...lower position and clamping separation mechanism CI, C2...upper left and right operating means Dl, D2...lower left and right operation initial means E...transfer mechanism El ...Guiding means F...
Dispensing pump gastric WS mechanism SO, SL, S2...sensate...magazine box 1a...fitting stock chamber 1b...
...Bottom 1c...Extraction hole 2...Guide plate 3...
・Slide plate 3a, 3b... Pit holes 71-7...
- Holding piece 8... Holding plate 8a-8b... Receiving hole
9...Dispensing pump 10...Nozzle 11,153.
・・Belt clamp 16.147・・Driven timing pulley 18.150・・Drive timing pulley 1
9.151...Timing bell 1-27...Guide roller 28...Backup roller 30.33...Guide rail 31...Slide groove 52...Short link 54...Lever 57...・
Solenoid 5B...Movable iron core 61...Return closing rack 140...Transfer body 143...Guide rod 1
45...Guide beam 146...Chip insertion work company 156.157...Reversible motor 158.159...Hanging shaft 158a, 159a...Rack 160.161...Binion 162.163...・Axis W

Claims (1)

[Scope of Claims] 1. At least one dispensing tip cassette containing a plurality of tip inserters in which a required number of two-stage flanged tips are loosely inserted vertically in parallel at equal pitch intervals is inserted into the stock chamber. The magazine box is inserted along guide plates that support and guide the lower ends of the chip series insert groups that protrude from the extraction holes that are inserted at equal pitches in the traveling direction of the bottom of the magazine box into which the magazine box is removably inserted. a magazine mechanism for pitch conveying, a slide mechanism for vertically dropping by releasing support for the lower end of the chip connecting body by means of a slide plate inserted between predetermined portions of the guide plate so as to be able to move back and forth intermittently; Directly below, there are two stages, upper and lower, which can be opened and closed, respectively. The upper and lower stage clamping and separating mechanism opens and closes and lowers the chips of the chip connecting body one by one from the bottom and separates them, and the lower stage and clamping and separating mechanism stops and waits just below the lower stage and vertically separates and drops the chips. A transfer mechanism that can freely reciprocate intermittently, receives and holds incoming chips in a receiving hole, transfers them to the chip insertion work position, and stops at the position, and a dispensing pump is installed from directly above the chips that are held and waiting at the chip insertion work position. A fully automatic chip supply/insertion device 2 in a dispensing machine, which is equipped with a dispensing pump elevating mechanism that pushes in the nozzle tip, inserts it, and raises it, a slide mechanism, a clamping separation mechanism, a transfer mechanism, and a dispensing pump elevating mechanism. The fully automatic chip supply/insertion device 3 and the magazine mechanism in the dispensing machine according to claim 1, wherein the mechanism is constructed to be able to freely process at least two or more chip serial inserts and separated chips, respectively. A feeding means for pitch-transporting horizontally along the guide plate, a locking means for immovably fixing the positioning stop, and a first support and guide means for smoothly supporting and guiding by regulating vertical, horizontal, longitudinal, and longitudinal vibrations during horizontal transport. The fully automatic tip supply/insertion device 4 in a dispensing machine according to claim 1 or 2, in which the support guide means is attached to the back side of the magazine box, respectively, and the slide mechanism is dropped on the front half side. One end of the link is pivotally connected to the rear end of the slide plate with a hole through it, and the other end of the link is pivotally connected to one end of the lever, while the other end of the lever, whose intermediate part is pivotally fixed, is connected to the outside of the movable core of the solenoid. One end of the lever is pivotally connected to the other, and one end of the repellent bar is attached to one end of the lever to constantly bias the outward movement of the movable core and the backward movement of the slide plate, so that when the slide plate is at its most retracted position, Claim 1, wherein the drop hole is formed so that the extraction hole penetrated through the bottom of the magazine box that has been positioned and stopped coincides with the drop hole.
The fully automatic chip supply/insertion device 5 in the dispensing machine described in item 2 or 3, the upper and lower stage clamping separation mechanism is an upper stage front and rear clamping piece in the upper and lower stage front and rear clamping pieces which are freely held in a manner that can be freely opened and closed in the front and rear directions. On the opposite edges of the two-stage flanged chip, the lower side of the upper flange and the lower front and rear clamping pieces have opposing semicircular holes that can hold the lower side of the lower flange of the chip, respectively. Upper and lower stage left and right operating means for operating the front and back, separation and opening/closing movements of the upper and lower stage front and rear clamping pieces are attached to the left and right ends of the clamping pieces, respectively;
Claims 1, 2, and 3, wherein the upper and lower stages of the front and rear clamping pieces are alternately movable to open and close, and the upper and lower stage left and right operating means are centrally driven and controlled by a single cam. Alternatively, in the fully automatic tip supply/insertion device 6 in the dispensing machine described in item 4, the transfer mechanism is a receiving hole that receives and inserts and holds the lower side of the lower flange of the tips separated and dropped by the upper and lower stages and the clamping separation mechanism. Claims 1 and 2 consist of a transporting body for fixing a holding plate having a penetrating body, a guide means for guiding and regulating the transporting body, and a feeding means for transporting the transporting body along the guide means. The fully automatic tip supply/insertion device 7 in the dispensing machine described in item 2, 3, 4, or 5, and the dispensing pump elevating mechanism include a suspension shaft on one side of which the dispensing pump is fixed to the lower end. A pinion that meshes with rack teeth extending in the direction is fixed to the outer end of the reversible motor shaft, and the hanging shaft is brought to the chip insertion work position, and the hanging shaft is lowered to wait at the chip insertion work position. The nozzle tip of the dispensing pump is pushed into the tip held in the receiving hole of the plate so that it can rise freely while the tip is inserted.
In the fully automatic tip feeding/inserting device 8 in the dispensing machine described in Section 3, Section 3, Section 4, Section 5, or Section 6, the tip insertion work position is such that the holding plate, which has been positioned at its most forward position and stopped, is at the upper end. Claims 1, 2, and 3, comprising a chip insertion work column erected so as to be freely supported.
Fully automatic tip feeding/insertion device in the dispensing machine according to paragraph 4, paragraph 5, paragraph 6 or paragraph 7