JPS61263910A - Hair cosmetic - Google Patents

Abstract

PURPOSE:A hair cosmetic, containing a specific germicide, e.g. pyrithione zinc, and extract of Luffa cylindrica together, capable of reducing the concentration of the above-mentioned germicide without deteriorating antidandruff effect and having improved safety. CONSTITUTION:A hair cosmetic, obtained by incorporating (A) an extract from Luffa cylindrica and (B) >=1 germicides selected from pyrithione zinc, triclosan, trichlorocarbanilide, salicylic acid, sodium benzoate, hinokitiol, photosensitive element, halocarban, chlorhexidine gluconate and benzalkonium chloride in a air cosmetic such as a shampoo in the following ratios based on the total cosmetic composition: >=0.005wt%, preferably >=0.01wt% component (A) and preferably 0.00001-5wt% component (B), and capable of adjusting metabolic reaction in scalp tissue appropriately to prevent significantly formation of dandruff and improving safety by decreasing remarkably the amount of said germicides to be used.

Description

[Detailed Description of the Invention] [Industrial Application Field] The present invention relates to hair cosmetics, and more specifically, contains a loofah extract, zinc pyrithione, triclosan, trichlorocarbanilide, salicylic acid, sodium benzoate, hinokitiol, photosensitizer, halo 1 selected from the group consisting of carban, chlorhexidine gluconate, and benzalkonium chloride
The present invention relates to a hair cosmetic for preventing dandruff, which is prepared by blending one or more species.

[Prior Art] Generally, dandruff consists of sebaceous gland secretions, sweat gland secretions, peeled substances from the epidermal layer, etc., and is usually caused by increased secretion of sebaceous glands, etc., but when the skin is infected with bacteria or yeast, dandruff The occurrence of this disease is said to be promoted pathologically. For this reason, hair cosmetics containing antibacterial agents have traditionally been used to prevent dandruff. For example, zinc pyrithione has traditionally been used as the most effective anti-dandruff agent, but it is well known that this substance also belongs to the category of antibacterial agents.

However, some of these antibacterial agents have safety problems, and it is considered preferable to avoid using large quantities as much as possible.

[Problems to be Solved by the Invention] In view of the above circumstances, the present inventors have worked diligently to obtain an anti-dandruff substance that is satisfactory in terms of skin safety and is comparable in effectiveness to zinc pyrithione. As a result of repeated research, they discovered that combining loofah extract with a known bactericidal and antibacterial substance is extremely useful for preventing dandruff, and can also improve safety, thereby completing the present invention. reached.

[Means for Solving the Problems] That is, the present invention uses loofah extract, zinc pyrithione, triclosan, trichlorocarbanilide, salicylic acid, sodium benzoate, hinokitiol, photosensitizer, halocarban, chlorhexidine gluconate, benzene chloride. A hair cosmetic containing one or more selected from the group consisting of ruconium.

Next, the configuration of the present invention will be explained in detail.

The loofah used in the present invention is a plant of the Cucurbitaceae family with the scientific name Luffa cyl.
indrica Roem) and its botanically related plants.

The loofah extract used in the present invention is obtained by cutting the whole loofah plant (preferably the loofah fruit) into pieces or using it as a raw material, and using a solvent such as water, a lower alcohol such as methyl alcohol or ethyl alcohol, and It can be obtained by concentrating the extract obtained by heating and refluxing it with a water-containing lower alcohol. A concentrate obtained by dissolving it in n-butyl alcohol, adding water, shaking and distributing it, and concentrating the obtained butyl alcohol phase can also be used as a loofah extract. A more specific example of the method for extracting the loofah extract is as follows.

5 kg of dried loofah fruit was directly added to 251 methyl alcohol and heated under reflux for 1 hour. This extract was filtered and concentrated under reduced pressure to obtain 64 g of methyl alcohol extract. 100ml of water was added to this dried extract to make it cloudy, and this was injected into a column filled with Amberlite XDA and allowed to flow down using water until the effluent became colorless. Next, methyl alcohol 21 was used for elution. The eluates were combined and the methyl alcohol was distilled off under reduced pressure, leaving a greenish brown residue 11.
g can be obtained.

The loofah extract thus obtained is a yellow-brown powder with a slightly pungent odor, and contains methyl alcohol.

It was easily soluble in ethyl alcohol and water, but poorly soluble in chloroform and acetone.

In the hair cosmetic of the present invention, loofah extract is blended in the total cosmetic composition in an amount of 0.005% by weight or more. Preferably it is 0.01% by weight or more.

On the other hand, substances used in combination with loofah extract include zinc pyrithione, triclosan, trichlorocarbanilide, sinothilic acid, sodium benzoate, hinokitiol, photosensitizer,
One or more of halocarban, chlorhexidine gluconate, and benzalkonium chloride, all of which are known substances.

In the hair cosmetic of the present invention, the above substances are added at 0.00%.
It is preferable to add 0.01% to 5% by weight.

When used alone, for example, zinc pyrithione is 0.5% by weight.
As mentioned above, hinokitiol is 0.3% by weight or more, triclosan is 0.1% by weight or more, and trichlorocarbanilide is 0.3% by weight or more.
The anti-dandruff effect is only achieved at 5% by weight or more, but
However, if large amounts of these substances are included, safety problems will occur as mentioned above, and stability problems will also arise in dispersed or dissolved systems, so large amounts of these substances should be avoided. I've never gotten over it.

In the present invention, loofah extract, which itself exhibits anti-dandruff effects at high concentrations, ie, 0.1% by weight or more, is used.
When used together with the above substance in a small amount of 0.005% by weight or more, the anti-dandruff effect can be exerted even when the concentration of the substance is as small as 0.0001% by weight.

In addition to the above-mentioned essential ingredients, the hair cosmetic of the present invention includes conventional ingredients such as oil, ultraviolet absorbers, surfactants, preservatives, humectants, fragrances, water, alcohol, thickeners,
Colorants, fragrances, etc. can be added as appropriate.

The hair cosmetics of the present invention broadly refer to those used for the scalp or hair, such as hair tonics, hair liquids (
Includes liquid hair wash), scalp emulsion, hair cream, hair shampoo, hair rinse, hair spray, etc.

[Effect] When the hair cosmetic of the present invention is used, the metabolic reactions within the scalp tissue can be moderately adjusted, and the occurrence of dandruff can be significantly prevented. , hinokitiol, photosensitizer, halocarban, chlorhexidine gluconate, and benzalkonium chloride can be significantly reduced in concentration.

[Example] Next, the present invention will be explained in more detail by referring to Examples and Experimental Examples. The present invention is not limited thereby. The blending amount is in weight%.

Experimental Example (method for measuring dandruff prevention effect) 0.005% by weight of loofah extract and 0.05% by weight of the above substance were blended into a shampoo, and the strength of the dandruff prevention effect was compared with a shampoo containing only these substances.

To 79.85 g of purified water, 15 g of triethanolamine lauryl sulfate, 5 g of coconut oil fatty acid jetanolamide, 0.05 g of the above substance, 0.005 g of loofah extract, and appropriate amounts of pigments and fragrances are sequentially added to 79.85 g of purified water, heated, and then cooled to make a hair shampoo. I got it.

Sixty-three men between the ages of 22 and 50 with relatively heavy dandruff were selected as subjects, and each sample was stratified into three men and tested.

Before the start of the test, the hair was washed with a drug-free shampoo, and after washing the hair, the accumulated dandruff for two days was collected, and the amount of protein in the collected dandruff was measured (control period).

Then, I used a shampoo containing chemicals for a month.
During this period, bald fins were collected and the amount of protein was measured in the same manner as in the control period (sample period).

Compare the average dandruff protein amount in the control period with the average dandruff protein amount in the sample period, and if the reduction rate of dandruff is 50% or more... A: 40% or more, but less than 50%.
...B: 20% or more, but less than 40%...0: Less than 20%: φ...D: Dandruff did not decrease: Ranked as E. The results are shown in Table 1.

As a result, it was found that dandruff could be significantly prevented by combining substances that had weak or no anti-dandruff effects when used alone.

(Margin below) Examples of the present invention are shown below.

Example 1 A shampoo consisting of the following formulation was prepared.

The manufacturing method is similar to the experimental example.

Lauryl sulfate-Ha 5.0
Lauryl sulfate - triethanolamine 5.0 Lauryldimethylaminoacetic acid betaine 6.0 Ethylene glycol fatty acid ester 2.0 Polyethylene glycol 5.0 Zinc pyrithione 0.08 Loofah extract
0.1 fragrance
0.3 water
A shampoo consisting of the remaining Examples and the following formulation was prepared.

The manufacturing method is the same as in Example 1.

Polyoxyethylene (EO average 3 moles) lauryl ether sulfate)-Ha 10.0 Polyoxyethylene (EO average 3 moles) lauryl ether sulfate-triethanolamine 7.0 Lauric acid jetanolamide 4.0 Dipropylene glycol 5 .0 Triclosan 0.005 Salicylic acid
0.05 loofah extract
0.1 fragrance
0.3 water
Remaining Example 3 A shampoo having the following formulation was prepared.

The manufacturing method is the same as in Example 1.

Lauroylmethyltaurine-Ha 10.0
Lauryldimethylaminoacetic acid betaine 8.0 Lauric acid diethanolamide 4.0 Ethylene glycol fatty acid ester 1.5 Polyethylene glycol 5.0 Hinokitiol
0.1 benzalkonium chloride
0.05 loofah extract
0.1 fragrance 0
．． 3 Water Residual Example 4 A shampoo consisting of the following formulation was prepared.

The manufacturing method is the same as in Example 1.

Cocoyl methyl taurine-Ha 10.0
Alkyl (C11) imidasolinium betaine type amphoteric activator 6.0 Coconut fatty acid diethanolamide 4.0 Polyoxyethylene polyoxypropylene block polymer 3,0 Benzalkonium chloride 0.3 Loofah extract 0.1 fragrance
0.3 water
Remaining Example 5 A shampoo having the following formulation was prepared.

The manufacturing method is the same as in Example 1.

Lauroylsarcosine-Ha 10.0
Lauryldimethylaminoacetic acid betaine 8.0 Lauric acid diethanolamide 4.0 Polyoxypropylene diglyl ether
5.0 halocarban
0.05 loofah extract
0.1 fragrance 0
．． 3 Water Residual The shampoos of Examples 1 to 5 all had excellent dandruff suppressing effects.

Examples 6 to 9, Comparative Examples 1 to 3 Hair rinses having the compositions listed in Table 2 were prepared,
We investigated its dandruff suppressing effect. The manufacturing method is based on Example 1.

Males between 22 and 36 years old were randomly selected as subjects, and the test was conducted on a total of 35 subjects, 5 for each sample.

The test was conducted using the above hair rinse after washing the hair with a shampoo that does not contain anti-dandruff drugs, and the weight of dandruff accumulated during the 3 days after hair washing before the start of the test and after the final hair wash at the end of the 1-month test were measured. The weight of dandruff accumulated over 3 days was compared, and when the dandruff reduction rate was 10% or less, it was determined that there was no effect. As shown in Table 2, the examples of the present invention exhibited excellent dandruff suppressing effects.

(Left below) Example 10 A hair tonic having the following composition was prepared. The manufacturing method involved mixing and stirring ingredients other than water, and adding this to water.

95χ ethyl alcohol (proprietary grade)
5.0 polyoxyethitone (40
mole) hydrogenated castor oil 0.5 photosensitive element 201
0.003 loofah extract
0.1 fragrance
0.5 water
Residual This hair tonic showed excellent dandruff control effect.

Example 11 A hair liquid (liquid hair wash) having the following formulation was prepared. The manufacturing method is similar to Example 10.

95χ ethyl alcohol (proprietary grade) 5.0 polyoxypropylene (40 mol) butyl ether
1.5 squalane
2.0 salicylic acid
0.3 loofah extract
0.1 Fragrance 0.5
Water Residual This hair liquid showed excellent dandruff control effect.

Example 12 A hair cream having the following composition was prepared. (A)
Part was heated and stirred, added to the similarly heated part (B) to emulsify, and then cooled to produce the product.

(A) Liquid paraffin 15.0 Cetyl alcohol 5.0 Vaseline 4.0 Glycystearate
3.0 polyoxyethylene (20
mole) oleyl alcohol
1.0 Sodium benzoate
0.5 Loofah extract 0
．． 1 fragrance 0.5
(B) Part Dipropylene Glycol 1.0 Water Residual O/
The W-type hair cream showed excellent dandruff suppressing effects.

Example 13 A hair lotion having the following composition was prepared. (A
) were mixed and stirred and added to part (B) to produce the product.

(A) Part 95% ethyl alcohol (proprietary grade)
40.0 dimethyl polysiloxane
0.5 liquid paraffin
0.5 Polyoxyethylene (40f Nyl) Hydrogenated Castor Oil 0.5 Acrylic 411111 Flukanolamine Liquid 0.5 Trichlorocarbanilide 0
．． 1 Zinc pyrithione 1.0 Loofah extract 1.0 Fragrance
0.2(B) part dipropylene glycol 3.0 water
Residual This hair lotion showed excellent dandruff control effect.

Example 14 A hair lotion having the following composition was prepared. The manufacturing method is based on Example 13.

(A) Part 95% ethyl alcohol (proprietary grade)
50.0 dimethyl polysiloxane
2.0 liquid paraffin
2.0 Stearyltrimethylammonium chloride 0.3 Hinokitiol 0.01 Loofah extract 0.1 Fragrance
0.2 parts (B) 1.3-butylene glycol 5.0 water remainder This hair lotion showed excellent dandruff control effect.

Claims (1)

[Claims] Luffa cylindrica extract and one selected from the group consisting of zinc pyrithione, triclosan, trichlorocarbanilide, salicylic acid, sodium benzoate, hinokitiol, photosensitizer, halocarban, chlorhexidine gluconate, and benzalkonium chloride.
A hair cosmetic containing one or more seeds.