JPS6087259A - Production of cysteamine - Google Patents
Production of cysteamineInfo
- Publication number
- JPS6087259A JPS6087259A JP19528383A JP19528383A JPS6087259A JP S6087259 A JPS6087259 A JP S6087259A JP 19528383 A JP19528383 A JP 19528383A JP 19528383 A JP19528383 A JP 19528383A JP S6087259 A JPS6087259 A JP S6087259A
- Authority
- JP
- Japan
- Prior art keywords
- cystamine
- metallic palladium
- hydrogen
- reducing
- cysteamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- UFULAYFCSOUIOV-UHFFFAOYSA-N Cysteamine Chemical compound NCCS UFULAYFCSOUIOV-UHFFFAOYSA-N 0.000 title 1
- 229940119025 Cysteamine Drugs 0.000 title 1
- 229960003151 Mercaptamine Drugs 0.000 title 1
- KDLHZDBZIXYQEI-UHFFFAOYSA-N palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 6
- 229940099500 Cystamine Drugs 0.000 abstract 3
- OOTFVKOQINZBBF-UHFFFAOYSA-N cystamine Chemical compound CCSSCCN OOTFVKOQINZBBF-UHFFFAOYSA-N 0.000 abstract 3
- 229910052763 palladium Inorganic materials 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 2
- 206010037759 Radiation injury Diseases 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003223 protective agent Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Abstract
PURPOSE: To produce the titled compound useful as a radiation injury protecting agent, etc., economically in an industrial scale, by reducing cystamine with hydrogen in the presence of metallic palladium.
CONSTITUTION: The objective compound is produced by reducing cystamine with hydrogen in a solvent such as methanol in the presence of a metallic palladium catalyst. The reaction is preferably carried out at 30W150°C under atmospheric pressure W20kg/cm2, usually for 1W10hr. The amount of the metallic palladium is preferably 2W10wt% based on the carrier, and 0.001W0.05g-atom per 1mol of cystamine.
EFFECT: Little by-products, simple purification, and high yield.
COPYRIGHT: (C)1985,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19528383A JPS6344741B2 (en) | 1983-10-20 | 1983-10-20 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19528383A JPS6344741B2 (en) | 1983-10-20 | 1983-10-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6087259A true JPS6087259A (en) | 1985-05-16 |
| JPS6344741B2 JPS6344741B2 (en) | 1988-09-06 |
Family
ID=16338577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP19528383A Expired JPS6344741B2 (en) | 1983-10-20 | 1983-10-20 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6344741B2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT201900025186A1 (en) * | 2019-12-23 | 2021-06-23 | Farmabios Spa | Method for the purification of cysteamine |
-
1983
- 1983-10-20 JP JP19528383A patent/JPS6344741B2/ja not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT201900025186A1 (en) * | 2019-12-23 | 2021-06-23 | Farmabios Spa | Method for the purification of cysteamine |
| EP3842418A1 (en) | 2019-12-23 | 2021-06-30 | Farmabios S.p.A. | Method for the purification of cysteamine |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6344741B2 (en) | 1988-09-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS6087259A (en) | Production of cysteamine | |
| JPS5699440A (en) | Preparation of 3-alkoxy-4-hydroxyphenylacetic acid | |
| JPS5576891A (en) | Production of methoxysilane | |
| JPS58198431A (en) | Preparation of 2-alkoxy-alcohol | |
| JPS5246026A (en) | Process for preparation of isocyanate compounds | |
| JPH01193277A (en) | Method to catalyze reaction of hydrosilation | |
| JPH0193549A (en) | Production of 1,1,1,2-tetrafluoroethane | |
| JPS6011438A (en) | Production of ethylene glycol dialkyl ether | |
| JPS5257128A (en) | Process for p-phenylenediamine | |
| JPS52122310A (en) | Synthesis of vinyl fluoride | |
| JPS63208592A (en) | Production of trialkoxysilane | |
| JPS52139036A (en) | Synthesis of 2-phenylpropionic acid derivatives | |
| JPS63297363A (en) | Production of 3-methylindoles | |
| JPS58185550A (en) | Preparation of ethylene cyanohydrin | |
| JPS5346912A (en) | Preparation of acetyl halides | |
| JPH04120052A (en) | Production of mercaptamines | |
| JPS5484550A (en) | Production of urethane | |
| JPS5699448A (en) | Preparation of lower alkoxyaniline | |
| JPS60115536A (en) | Production of fluoromethane | |
| JPS5885829A (en) | Preparation of 2-trifluoromethylpropanol | |
| JPS59190975A (en) | Production of 2-alkyl-4-amino-5-aminomethylpyrimidine | |
| JPS6185343A (en) | Selective production of methyl isobutyl ketone | |
| JPS57130937A (en) | Synthetic method of alkane polyol | |
| JPH0429987A (en) | Production of 1, 3-oxathiolane compound | |
| JPS5414920A (en) | Synthesis of carbonate |