JPS58189122A - 高脂血症予防治療剤 - Google Patents

高脂血症予防治療剤

Info

Publication number
JPS58189122A
JPS58189122A JP57071494A JP7149482A JPS58189122A JP S58189122 A JPS58189122 A JP S58189122A JP 57071494 A JP57071494 A JP 57071494A JP 7149482 A JP7149482 A JP 7149482A JP S58189122 A JPS58189122 A JP S58189122A
Authority
JP
Japan
Prior art keywords
agent
hyperlipidemia
pronase
disease
arteriosclerosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57071494A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0213647B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
Shigemi Fujisaki
藤崎　茂巳
Takashi Fujisaki
藤崎　隆司
Junichi Yoshida
淳一 吉田
Yasuhiro Fujisaki
藤崎　恭大
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kaken Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaken Pharmaceutical Co Ltd filed Critical Kaken Pharmaceutical Co Ltd
Priority to JP57071494A priority Critical patent/JPS58189122A/ja
Priority to US06/484,313 priority patent/US4440749A/en
Priority to GB08310184A priority patent/GB2121685B/en
Priority to DE19833315482 priority patent/DE3315482A1/de
Priority to FR8307188A priority patent/FR2525901B1/fr
Publication of JPS58189122A publication Critical patent/JPS58189122A/ja
Publication of JPH0213647B2 publication Critical patent/JPH0213647B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/2404—Serralysin (3.4.24.40)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP57071494A 1982-04-30 1982-04-30 高脂血症予防治療剤 Granted JPS58189122A (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP57071494A JPS58189122A (ja) 1982-04-30 1982-04-30 高脂血症予防治療剤
US06/484,313 US4440749A (en) 1982-04-30 1983-04-12 Preventive and treating agent for blood lipids abnormality and/or arteriosclerosis
GB08310184A GB2121685B (en) 1982-04-30 1983-04-14 Protease compositions for treating blood lipids abnormality and arteriosclerosis
DE19833315482 DE3315482A1 (de) 1982-04-30 1983-04-28 Mittel zur verhinderung und behandlung von blutlipid-abnormalitaet und/oder arteriosclerose
FR8307188A FR2525901B1 (fr) 1982-04-30 1983-04-29 Agent de prophylaxie et de traitement des anomalies des lipides sanguins et/ou de l'arteriosclerose, a base d'une enzyme proteolytique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57071494A JPS58189122A (ja) 1982-04-30 1982-04-30 高脂血症予防治療剤

Publications (2)

Publication Number Publication Date
JPS58189122A true JPS58189122A (ja) 1983-11-04
JPH0213647B2 JPH0213647B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1990-04-04

Family

ID=13462269

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57071494A Granted JPS58189122A (ja) 1982-04-30 1982-04-30 高脂血症予防治療剤

Country Status (5)

Country Link
US (1) US4440749A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS58189122A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3315482A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2525901B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2121685B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6261926A (ja) * 1985-09-13 1987-03-18 Hiroshi Maeda 制癌剤
FR2646605A1 (fr) * 1989-05-08 1990-11-09 Shigemi Fujisaki Activateur de neurones endommages, servant a la prevention et au traitement de maladies

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116615A (en) * 1989-01-27 1992-05-26 Immunolytics, Inc. Method for treating benign prostatic hypertrophy
WO1990008555A1 (en) 1989-01-27 1990-08-09 Immunolytics, Inc. Composition and method for treating benign prostatic hypertrophy
NL9201842A (nl) * 1992-10-23 1994-05-16 Teng Hian Khoe Toepassing van een papaine bevattend voedingssupplement voor therapeutische behandeling van AIDS aandoeningen.
GB9403344D0 (en) * 1994-02-22 1994-04-13 Cortecs Ltd Medical application of bromelain
DE102005002255A1 (de) 2005-01-18 2006-07-20 Rehau Ag + Co. Wandanschlussprofil

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5473107A (en) * 1977-11-24 1979-06-12 Keigo Takeda Germicide for special coccus *not disinfected one kind of antibiotics*
JPS5543040A (en) * 1978-09-25 1980-03-26 Eisai Co Ltd Immunity raising agent
JPS5826822U (ja) * 1981-08-17 1983-02-21 株式会社クボタ 刈取収穫機

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB753134A (en) * 1952-09-17 1956-07-18 Nat Drug Co An injectable trypsin containing pharmaceutical composition and method for its production
GB894151A (en) * 1958-01-29 1962-04-18 American Cyanamid Co Preparation of high purity streptokinase
US3224942A (en) * 1962-01-15 1965-12-21 Rorer Inc William H Anti-inflammatory, anti-edema and anti-thrombi drug
DE1249797B (de) * 1963-06-29 1967-09-14 Behringwerke Aktiengesellschaft, Marburg/Lahn Verfahren zur Herstellung von Streptokinase-Präparaten verminderter Antigenität
US3355361A (en) * 1964-10-15 1967-11-28 Sterling Drug Inc Recovery and purification of urokinase
GB1139991A (en) * 1965-07-19 1969-01-15 Armour Pharma Stabilized enzyme composition
GB1185335A (en) * 1967-05-30 1970-03-25 Takeda Chemical Industries Ltd A method for producing Protease
GB1263956A (en) * 1969-09-26 1972-02-16 Ici Ltd Enzymes
GB1274604A (en) * 1971-02-18 1972-05-17 Wilson Pharm & Chem Corp Pancreatin composition and method of preparation
AU469815B2 (en) * 1971-04-14 1973-10-18 Anti-inflammatory compositions
JPS5443074B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1971-04-14 1979-12-18
BE786788A (fr) * 1971-07-27 1973-01-26 Rhone Poulenc Sa Nouvelle enzyme thrombolytique et sa preparation par fermentation d'un streptomyces
JPS5039151B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1972-09-02 1975-12-15
GB1479268A (en) * 1973-07-05 1977-07-13 Beecham Group Ltd Pharmaceutical compositions
GB1448276A (en) * 1973-09-15 1976-09-02 Eisai Co Ltd Elastase and methods for using same
US4082612A (en) * 1976-09-24 1978-04-04 Michael Reese Research Foundation Plasminogen activator complex
IT1170913B (it) * 1981-04-23 1987-06-03 Manetti & Roberts Italo Brit Procedimento per la produzione di un principio attivo fibrinolitico vasale prodotto enzimatico specifico angiochinasi cosi' ottenuto e sue applicazioni farmaceutiche

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5473107A (en) * 1977-11-24 1979-06-12 Keigo Takeda Germicide for special coccus *not disinfected one kind of antibiotics*
JPS5543040A (en) * 1978-09-25 1980-03-26 Eisai Co Ltd Immunity raising agent
JPS5826822U (ja) * 1981-08-17 1983-02-21 株式会社クボタ 刈取収穫機

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6261926A (ja) * 1985-09-13 1987-03-18 Hiroshi Maeda 制癌剤
FR2646605A1 (fr) * 1989-05-08 1990-11-09 Shigemi Fujisaki Activateur de neurones endommages, servant a la prevention et au traitement de maladies
DE3941324A1 (de) * 1989-05-08 1990-11-15 Shigemi Fujisaki Aktivator fuer verletzte neurozyten zur verhuetung und behandlung von krankheiten
DE3941324C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1989-05-08 1992-06-25 Fujisaki, Shigemi, Nishinomiya, Hyogo, Jp
DE3943649C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1989-05-08 1992-10-29 Fujisaki, Shigemi, Nishinomiya, Hyogo, Jp

Also Published As

Publication number Publication date
DE3315482C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1992-07-16
GB8310184D0 (en) 1983-05-18
GB2121685A (en) 1984-01-04
US4440749A (en) 1984-04-03
FR2525901B1 (fr) 1988-08-26
FR2525901A1 (fr) 1983-11-04
GB2121685B (en) 1986-05-21
DE3315482A1 (de) 1984-01-12
JPH0213647B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1990-04-04

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