JPS58177659A - Blood treating apparatus - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION This invention extracts blood from a patient and supplies it to a blood processor;
Regarding blood processing equipment equipped with an extracorporeal circulation circuit that returns processed blood to the patient. Currently, such blood processing equipment includes dialysis-type or filtration-type artificial kidneys, artificial lungs, artificial liver failure, and plasma separators. has been made into After blood processing is completed in such a blood processing apparatus, it is necessary to return the blood remaining in the extracorporeal circulation circuit to the patient. The amount of residual blood is, for example, as much as 100 to 300 mj, and since the patient's own blood cell capacity is reduced, it is preferable to collect this blood into the patient without leaving as much of it as possible.

For this reason, conventionally, during blood collection operations, staff members apply vibrations to the blood tubes and blood processing equipment that make up the extracorporeal circulation circuit to peel off the blood adhering to the inside and return it to the body. was going on. In addition, when using this blood processing device, sufficient sterilization is performed, and 42 formalin or ethylene oxide gas is used for the sterilization. It is necessary to thoroughly wash away such disinfectants, and it is desirable to carry out the washing effectively.The purpose of the present invention is to effectively and efficiently remove the substances adhering to the inside of the blood processing device. The purpose of the present invention is to provide a blood processing device that does the following.

According to the present invention, means is provided which can repeatedly and periodically change the flow rate of blood within the blood processing device. As a means for this purpose, for example, a means for blocking the flow at the outlet side of the blood processing device, or a means for opening the block, is provided, and when the flow is opened, the fluid pressure that has increased is suddenly released, and the flow rate is suddenly increased. or the rotational speed of the pump supplying liquid to the blood processor may be rapidly changed.
Each time this rapid change in the flow rate of the liquid in the blood processing device is repeated, a shock is applied to the inside of the blood processing device, which effectively removes blood and other substances adhering to the blood processing device. becomes possible.

Next, an embodiment of the blood processing apparatus according to the present invention will be described with reference to the drawings. In FIG. 1, an artery needle attached to one end of a blood pipe 12 is inserted into the artery of a patient 11, and blood is drawn out from the patient 11J.

The other end of the pipe 12 is connected to a drip chamber 13. A roller pump 14 is provided in the middle of the pipe 12, and by rotating this pump 14i, the patient 11 is
19 The increased blood is supplied to the drip chamber 13. Air is separated from the blood supplied to the drip chamber 13, and the blood that has passed through the drip chamber 13 is processed by a blood processor 15 such as a dialysis machine. This treated blood is supplied to the drip chamber 16 to remove air bubbles, and the blood that has left the drip chamber 16 is drawn into a blood pipe 17t-a and into the patient's body through an intravenous needle provided freely in the pipe 17. will be returned to. In this way, an extracorporeal circulation port IN118 is constructed which extends from the pipe 12 to the blood processing ft15 and the pipe 17.

Two pumps 19 are provided on the patient side of the pump 14 as means for controlling the flow of the blood pipe 12 on and off.

Similarly, a clamp 21 is provided on the pipe 17, and an air bubble detector 22 is arranged in the drip chamber 161H of the pump 21. When air bubbles are present in the blood passing through the pipe 17, the air bubble detector 22 is detected and the clamp 21 is closed.

When the blood treatment is completed, the blood in the extracorporeal circulation circuit 18 is collected into the patient 11. For this purpose, the arterial needle that has been inserted into the patient 11 is removed and inserted into the saline bottle 23 as shown by the dotted line. In this state, clamp 19.21 is
The pump 14 is opened as shown in FIG. 2, that is, the extracorporeal circulation circuit 18 is in a circulating state, and the pump 14 is operated as shown in FIG. Therefore, physiological saline is supplied to the blood processor 15 through the blood pipe 121,
Pipe 12. Blood existing in the blood processing device 15 or the like is pushed out and returned to the patient 11. This physiological saline supply t is made to approximately match the liquid volume within the extracorporeal circulation circuit 18.

When the amount of physiological saline supplied to the kernel reaches a predetermined value as shown in Figure 2, clamp the mushroom at that point 19.21.
Close both parts as shown in Figure 2A and No. 8. In this embodiment, the liquid within the tmXv extracorporeal circulation circuit 18 is circulated at one point in time without passing through the patient 11. For this purpose, a bypass pipe 24 is connected between the blood pipe 12 between the pump 14 and the clamp 19 and the blood pipe 17 between the drip chamber 16 and the bubble detector 22, and the I11 clamp 25 is provided on the 1-circuit pipe 24. . As shown in the second diagram, at time ts, the reclap/pipe 25 is closed, stopping the flow of blood in the side pipe 24, and from time t8 @
The flow of the pipe 24 is allowed. Therefore, by driving the pump 14, the pipe 12. Chamber 13, blood processor 1
5. Chamber 16. A sub-circulation circuit 26t consisting of pipes 17 and 24 circulates the liquid, and this circulation effectively removes the blood adhering to the inside, especially the blood processing device 15.

After this secondary circulation wI26 has been circulated for a certain period of time, at time ts, the clamp 25 is closed as shown in the second diagram, and the clamps 19 and 21 are opened as shown in FIGS. 2A and H, respectively.1 Extracorporeal circulation circuit 1st circulation state, subcirculation circuit 26
It1 circulation is stopped. Physiological saline is again supplied to the extracorporeal circulation circuit 18, and the saline containing the blood that has been peeled off from the inner wall of the extracorporeal circulation circuit 18 is supplied to the patient 11.

In this invention, the flow rate t of the liquid in the t1 blood processing device 15 is
-Repeated rapid number changes. Therefore, in this example, a clamp 27 is provided on the blood outflow path of the blood processing device 15,
This clamp 27i is repeatedly turned on and off. Further, in this example 2, the clamp 27 is opened when the arterial pressure reaches the set upper limit, and is closed when the arterial pressure reaches the set lower limit.

For this purpose, the drip chamber 134 and the arterial pressure detector 28
is provided, whereby the detected arterial pressure II is supplied to a comparator 29.31. Comparison fi29゜31 has terminals 32.33 respectively! When the detected pressure of the arterial pressure detector 28, which has a lower limit set value and an upper limit set value, respectively, becomes less than the lower limit set value, the output of the comparison circuit 29 becomes a high level, and the flip-flop 34 is set.
This set output is given to wI 35 once for control, causing the control circuit 35 to close the ef-ramp 27.

As shown in FIG.
This causes the pressure inside the blood processing device 15 to reach the second level.
It rises as shown in Figure F. When this pressure exceeds the upper limit setting, the output of the comparator 31 goes high and the output lip frog 34 is reset. This reset causes the control circuit 35 to open the clamp 27. When the clamp 27 is opened, the liquid pressure in the blood processing device 6, which had been high up until then, is suddenly released, so that the blood suddenly flows and its flow rate increases. The impact of this flow causes the blood adhering to the wall surface of the blood processing device 15 to fall off.

When the clamp 27 is opened, the pressure of the artery detection lever 28 is increased! As shown in Figure 2F, the lower value gradually decreases to 9, and when this reaches the lower limit, the output of comparison 1iiF29 becomes a high level, and the flip-frog 34 is set again to clamp 2.
7 is closed. As this process is repeated, the flow velocity 12 in the blood processing device 15 increases rapidly, and the blood adhering to the inner wall of the blood processing device 15 is washed away. Such an operation may be continued until the blood collection operation is completed as shown in FIG. At this point in time t4, the clamp 21 is closed.

These clamps 19, 21, 25, 27, etc. are controlled through the first control @u path 35. Further, the control circuit 35 detects the amount of saline supplied by the integrated value of the number of revolutions of the pump 14, or by the amount of change l in the level of the saline in the saline bottle 23. Also, time ts to ts
t2 is determined by setting a timer, for example. In order to rapidly change the flow velocity in the blood processing device 15, the pot clamp 27f was turned on and off, and the on/off control was performed by detecting the arterial pressure, but the lower limit and upper limit settings were changed depending on the blood processing device. ◎1) It is possible to control the pump 27 on and off at an appropriate repetition rate without having to make these settings each time. <Calm down,
In love time * # ILll 1V meeting ffur # MmnJ
9. In such a blood processing apparatus 1a, even when cleaning the sterilizing agent after washing, it is possible to efficiently perform the cleaning by rapidly changing the flow rate inside the blood processing apparatus. In this way, the flow rate in the blood processing device 15 can be rapidly changed not only by changing the pressure in the blood processing device 15 by turning on and off the pump 27, but also by rapidly increasing the rotational speed of the pump 14, for example. You may repeatedly increase or decrease the value. If you want to change the flow rate rapidly depending on the rotation speed of this pump.

It is effective to insert a pump between the blood processor 15 and the chamber 13 or 1216 and to rapidly change the rotation of the pump.

[Brief explanation of the drawing]

FIG. 1 is a configuration diagram showing an example of a blood processing apparatus according to the present invention, and FIG. 2 is a time chart for explaining its operation. 11: Patient, 12.17: Blood pipe, 13°16 = Drip chamber, 15: Blood processor, 14: Pump, 1
8: Extracorporeal circulation (b) path, 19°21.25.27: Clamp, 22: Air bubble detector, 28: Arterial pressure detector, 29.
31: Comparator. 34: Flip frog% 35: Control circuit. Patent applicant Asahi Medical Co., Ltd. Agent Taku Kusano Procedural amendment (voluntary) July 21, 1980 Commissioner of the Patent Office Tono 1, Case indication Patent-Sho 57-605962, Title of invention Blood treatment device 3, ? *Relationship with the case of correctional care Patent applicant: Asahi Medical Co., Ltd. 4, Agent: 4-2-21 Shinjuku, Shinjuku-ku, Tokyo
Sumo Building 5, subject of amendment Contents of Claims in the Specification and Detailed Description of the Invention column 6 Yusho (11 Claims are corrected as shown in the attached sheet. (21 Specification, page 2, line 14) “Flow rate of blood” is changed to “liquid (3)”
) The same book, page 7, line 18, "Blood is sudden (: flowing,") is corrected to "liquid is sudden 4: flowing." Claims (1) Blood having an extracorporeal circulation circuit in which a blood processing device is inserted The blood processing device l1t- is characterized in that the blood processing device is provided with means for periodically and rapidly changing the flow rate of the liquid in the blood processing device.

Claims (1)

[Claims] (1) A blood processing device having an extracorporeal circulation circuit into which a blood processing device is inserted, characterized in that a blood processing device is provided with at least means for rapidly changing the flow of blood in the blood processing device periodically. Processing equipment.