JPS5759878A - Alkyl- and cycloalkyl-substituted 2-(2-(2- hydroxy-3-t-butylamino-propoxy)-5-acylamino- phenyl)-1,3,4-oxadiazole, manufacture and drug containing same - Google Patents
Alkyl- and cycloalkyl-substituted 2-(2-(2- hydroxy-3-t-butylamino-propoxy)-5-acylamino- phenyl)-1,3,4-oxadiazole, manufacture and drug containing sameInfo
- Publication number
- JPS5759878A JPS5759878A JP56126024A JP12602481A JPS5759878A JP S5759878 A JPS5759878 A JP S5759878A JP 56126024 A JP56126024 A JP 56126024A JP 12602481 A JP12602481 A JP 12602481A JP S5759878 A JPS5759878 A JP S5759878A
- Authority
- JP
- Japan
- Prior art keywords
- cycloalkyl
- butylamino
- acylamino
- oxadiazole
- propoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 230000006793 arrhythmia Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
- C07C243/38—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19803030530 DE3030530A1 (de) | 1980-08-13 | 1980-08-13 | Alkyl- und cycloalkylsubstituierte 2-(2-(-hydroxy-3-tert-butylamino-propoxy)-5-acylaminophenyl)-1,3,4-oxadiazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische zubereitungen |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5759878A true JPS5759878A (en) | 1982-04-10 |
Family
ID=6109480
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56126024A Pending JPS5759878A (en) | 1980-08-13 | 1981-08-13 | Alkyl- and cycloalkyl-substituted 2-(2-(2- hydroxy-3-t-butylamino-propoxy)-5-acylamino- phenyl)-1,3,4-oxadiazole, manufacture and drug containing same |
Country Status (7)
Country | Link |
---|---|
US (1) | US4409232A (ja) |
EP (1) | EP0045955B1 (ja) |
JP (1) | JPS5759878A (ja) |
AT (1) | ATE4541T1 (ja) |
AU (1) | AU7384381A (ja) |
CA (1) | CA1164870A (ja) |
DE (2) | DE3030530A1 (ja) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3423429A1 (de) * | 1984-06-26 | 1986-01-02 | Beiersdorf Ag, 2000 Hamburg | Substituierte phenoxyalkylaminopropanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen |
JPH0553264A (ja) * | 1991-08-23 | 1993-03-05 | Konica Corp | ハロゲン化銀カラー写真感光材料 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE439104A (ja) | 1939-06-22 | |||
DE842346C (de) | 1950-10-14 | 1952-06-26 | Joachim Dipl-Chem Dr Goerdeler | Verfahren zur Darstellung von 5-Amino-1, 2, 4-thiodiazolen |
US2648669A (en) * | 1951-05-29 | 1953-08-11 | American Cyanamid Co | Reaction product of sodium dicyanamide and hydroxylamine hydrochloride |
DE1670924B2 (de) | 1967-09-19 | 1976-11-18 | Bayer Ag, 5090 Leverkusen | 1,2,4-thiadiazolyl-harnstoffderivate |
HU169666B (ja) | 1973-12-29 | 1977-02-28 | ||
DE2811638A1 (de) * | 1978-03-17 | 1979-09-20 | Beiersdorf Ag | Substituierte aryloxy-aminopropanole und verfahren zu deren herstellung |
DE3005287A1 (de) * | 1980-02-13 | 1981-08-20 | Basf Ag, 6700 Ludwigshafen | Phenylpiperazinderivate von 1,3,4-oxadiazolylphenolen, ihre herstellung und diese enthaltende therapeutische mittel |
-
1980
- 1980-08-13 DE DE19803030530 patent/DE3030530A1/de not_active Withdrawn
-
1981
- 1981-08-06 AU AU73843/81A patent/AU7384381A/en not_active Abandoned
- 1981-08-07 DE DE8181106178T patent/DE3160821D1/de not_active Expired
- 1981-08-07 EP EP81106178A patent/EP0045955B1/de not_active Expired
- 1981-08-07 US US06/290,952 patent/US4409232A/en not_active Expired - Fee Related
- 1981-08-07 AT AT81106178T patent/ATE4541T1/de not_active IP Right Cessation
- 1981-08-12 CA CA000383758A patent/CA1164870A/en not_active Expired
- 1981-08-13 JP JP56126024A patent/JPS5759878A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE3030530A1 (de) | 1982-03-18 |
US4409232A (en) | 1983-10-11 |
DE3160821D1 (en) | 1983-10-06 |
EP0045955B1 (de) | 1983-08-31 |
ATE4541T1 (de) | 1983-09-15 |
EP0045955A1 (de) | 1982-02-17 |
AU7384381A (en) | 1982-02-18 |
CA1164870A (en) | 1984-04-03 |
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