JPS5753076B2 - - Google Patents

Info

Publication number
JPS5753076B2
JPS5753076B2 JP51148299A JP14829976A JPS5753076B2 JP S5753076 B2 JPS5753076 B2 JP S5753076B2 JP 51148299 A JP51148299 A JP 51148299A JP 14829976 A JP14829976 A JP 14829976A JP S5753076 B2 JPS5753076 B2 JP S5753076B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP51148299A
Other versions
JPS5373501A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to JP51148299A priority Critical patent/JPS5753076B2/ja
Publication of JPS5373501A publication Critical patent/JPS5373501A/ja
Publication of JPS5753076B2 publication Critical patent/JPS5753076B2/ja
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces
JP51148299A 1976-12-11 1976-12-11 Expired JPS5753076B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP51148299A JPS5753076B2 (ja) 1976-12-11 1976-12-11

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP51148299A JPS5753076B2 (ja) 1976-12-11 1976-12-11
US05/855,379 US4107297A (en) 1976-12-11 1977-11-28 Antibiotic compound
GB49874/77A GB1542995A (en) 1976-12-11 1977-11-30 Antibiotic compound
DE2754326A DE2754326C2 (ja) 1976-12-11 1977-12-06
FR7737034A FR2373556B1 (ja) 1976-12-11 1977-12-08
CH1523477A CH634103A5 (de) 1976-12-11 1977-12-12 Verfahren zur herstellung des neuen antibiotikums am-2282.

Publications (2)

Publication Number Publication Date
JPS5373501A JPS5373501A (en) 1978-06-30
JPS5753076B2 true JPS5753076B2 (ja) 1982-11-11

Family

ID=15449664

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51148299A Expired JPS5753076B2 (ja) 1976-12-11 1976-12-11

Country Status (6)

Country Link
US (1) US4107297A (ja)
JP (1) JPS5753076B2 (ja)
CH (1) CH634103A5 (ja)
DE (1) DE2754326C2 (ja)
FR (1) FR2373556B1 (ja)
GB (1) GB1542995A (ja)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735939A (en) * 1987-02-27 1988-04-05 The Dow Chemical Company Insecticidal activity of staurosporine
US5093330A (en) * 1987-06-15 1992-03-03 Ciba-Geigy Corporation Staurosporine derivatives substituted at methylamino nitrogen
USRE36736E (en) * 1989-02-06 2000-06-13 Hoffman-La Roche Inc. Substituted pyrroles
IL89167A (en) * 1988-02-10 1994-02-27 Hoffmann La Roche Substituted pyrroles, their manufacture and pharmaceutical compositions containing them
GB8904161D0 (en) * 1989-02-23 1989-04-05 Hoffmann La Roche Substituted pyrroles
US5015578A (en) * 1989-03-23 1991-05-14 Bristol-Myers Squibb Company BMY-41950 antitumor antibiotic
US5618809A (en) * 1989-12-14 1997-04-08 Schering Corporation Indolocarbazoles from saccharothrix aerocolonigenes copiosa subsp. nov SCC 1951 ATCC 53856
US4973552A (en) * 1990-02-20 1990-11-27 Bristol-Meyers Squibb Company Staurosporine fermentation process
US5292747A (en) * 1990-08-07 1994-03-08 Hoffman-La Roche Inc. Substituted pyrroles
AU2866992A (en) * 1991-10-10 1993-05-03 Schering Corporation 4'-(n-substituted-n-oxide)staurosporine derivatives
WO1993018771A1 (en) * 1992-03-24 1993-09-30 Asahi Kasei Kogyo Kabushiki Kaisha PLATELET AGGLUTINATION INHIBITOR CONTAINING STAUROSPORINE η-LACTAM DERIVATIVE
CA2123895A1 (en) * 1992-09-21 1994-03-31 Tatsuya Tamaoki A therapeutic agent for thrombocytopenia
US7097972B1 (en) 1995-02-13 2006-08-29 Regents Of The University Of Michigan Method and composition for regulating apoptosis
US6060238A (en) * 1995-02-13 2000-05-09 The Regents Of The University Of Michigan Method and composition for regulating apoptosis
US6015665A (en) * 1995-02-13 2000-01-18 The Regents Of The University Of Michigan Method and composition for regulating apoptosis
US6747138B1 (en) 1995-04-03 2004-06-08 Regents Of The University Of Michigan Methods and compositions for regulating Fas-associated apoptosis
DE19917990A1 (de) * 1999-04-20 2000-11-02 Florian Lang Arzneimittel enthaltend Hemmstoffe der zellvolumenregulierten humanen Kinase h-sgk
US6524577B1 (en) * 2000-09-27 2003-02-25 Agraquest, Inc. Strain of Streptomyces for controlling plant diseases
WO2004094645A1 (en) * 2003-04-22 2004-11-04 Lonza Ag Process for the recovery of staurosporine from a fermentation broth
JO2897B1 (en) * 2004-11-05 2015-09-15 نوفارتيس ايه جي Organic compounds
CN101580515B (zh) * 2008-05-16 2011-06-08 上海医药工业研究院 一种星形孢菌素提取纯化的方法
WO2018165071A1 (en) 2017-03-06 2018-09-13 Teva Pharmaceutical Works Ltd. Solid state forms of midostaurin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3843784A (en) * 1970-12-24 1974-10-22 Lilly Co Eli Antibiotics a201a and a201b and process for the production thereof
JPS4710038U (ja) * 1971-02-26 1972-10-06
BE795918A (fr) * 1972-02-29 1973-08-27 Lilly Co Eli Antibiotique a-25822 et procede de production

Also Published As

Publication number Publication date
FR2373556B1 (ja) 1980-08-22
DE2754326C2 (ja) 1982-10-21
US4107297A (en) 1978-08-15
DE2754326A1 (de) 1978-06-15
CH634103A5 (de) 1983-01-14
JPS5373501A (en) 1978-06-30
GB1542995A (en) 1979-03-28
FR2373556A1 (fr) 1978-07-07

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